SG11201503020TA - A novel reagent for gene-drug therapeutics - Google Patents
A novel reagent for gene-drug therapeuticsInfo
- Publication number
- SG11201503020TA SG11201503020TA SG11201503020TA SG11201503020TA SG11201503020TA SG 11201503020T A SG11201503020T A SG 11201503020TA SG 11201503020T A SG11201503020T A SG 11201503020TA SG 11201503020T A SG11201503020T A SG 11201503020TA SG 11201503020T A SG11201503020T A SG 11201503020TA
- Authority
- SG
- Singapore
- Prior art keywords
- gene
- novel reagent
- drug therapeutics
- therapeutics
- drug
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261719908P | 2012-10-29 | 2012-10-29 | |
| PCT/SG2013/000464 WO2014070111A1 (en) | 2012-10-29 | 2013-10-29 | A novel reagent for gene-drug therapeutics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201503020TA true SG11201503020TA (en) | 2015-05-28 |
Family
ID=50627830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201503020TA SG11201503020TA (en) | 2012-10-29 | 2013-10-29 | A novel reagent for gene-drug therapeutics |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10100331B2 (en) |
| EP (1) | EP2911650B1 (en) |
| JP (1) | JP6342910B2 (en) |
| CN (1) | CN105101951B (en) |
| DK (1) | DK2911650T3 (en) |
| SG (1) | SG11201503020TA (en) |
| WO (1) | WO2014070111A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2911650B1 (en) | 2012-10-29 | 2019-09-04 | Agency For Science, Technology And Research | A novel reagent for gene-drug therapeutics |
| JP6231709B1 (en) | 2016-05-31 | 2017-11-15 | シスメックス株式会社 | Fluorescence image analyzer and analysis method |
| CN108611355B (en) * | 2018-05-04 | 2021-08-31 | 北京锦篮基因科技有限公司 | Gene medicine for X chromosome linked myotubule myopathy |
| SG10201902002SA (en) * | 2019-03-06 | 2020-10-29 | Nat Univ Singapore | Non-viral modification of mesenchymal stem cells |
| GB201903873D0 (en) * | 2019-03-21 | 2019-05-08 | Univ Nottingham | Enhanced transfection |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0599850B1 (en) * | 1991-08-16 | 1996-01-10 | Vical, Inc. | Composition and method for treating cystic fibrosis |
| CA2411542A1 (en) | 2000-06-09 | 2001-12-13 | Teni Boulikas | Encapsulation of polynucleotides and drugs into targeted liposomes |
| KR100980153B1 (en) * | 2000-11-29 | 2010-09-03 | 피씨아이 바이오테크 에이에스 | Photochemical Internalization for Delivery of Molecules into the Cytosol |
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| CA2572439A1 (en) * | 2004-07-02 | 2006-01-12 | Protiva Biotherapeutics, Inc. | Immunostimulatory sirna molecules and uses therefor |
| US7745596B2 (en) * | 2004-07-12 | 2010-06-29 | Japan Science And Technology Agency | Nuclear transport nucleic acid delivery vector |
| US20060051405A1 (en) * | 2004-07-19 | 2006-03-09 | Protiva Biotherapeutics, Inc. | Compositions for the delivery of therapeutic agents and uses thereof |
| US20100022637A1 (en) * | 2005-09-29 | 2010-01-28 | The Trustees Of Columbia University In The City Of New York | Identification of anti-cancer compounds and compounds for treating huntington's disease and methods of treatment thereof |
| WO2007064163A1 (en) * | 2005-11-30 | 2007-06-07 | Jung Moon Kim | Non-activated wnt inhibition polypeptides and method for preparing the same |
| JP4182449B2 (en) * | 2006-03-29 | 2008-11-19 | 東洋紡績株式会社 | Method for reducing cell damage during nucleic acid introduction |
| WO2008103431A2 (en) * | 2007-02-23 | 2008-08-28 | Pronai Therapeutics, Inc. | Dnai - liposomes |
| ES2594102T3 (en) * | 2008-04-18 | 2016-12-15 | Vaxinnate Corporation | Mutants by flagelin deletion and methods for its use |
| US8802138B2 (en) * | 2009-10-12 | 2014-08-12 | Jessie L.-S. Au | Methods and compositions for improved deliver, expression or activity of RNA interference agents |
| JP2013518587A (en) * | 2010-02-04 | 2013-05-23 | ヴィヴォスクリプト，インコーポレイテッド | Compositions and methods for reprogramming cells without genetic modification to treat neurological disorders |
| WO2011130624A2 (en) * | 2010-04-16 | 2011-10-20 | Immune Disease Institute, Inc. | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| KR101242113B1 (en) * | 2010-10-22 | 2013-03-19 | 고마바이오텍(주) | Cationic Sendai F/HN viroplex for Gene Delivery |
| US20130090369A1 (en) * | 2011-10-06 | 2013-04-11 | Empire Technology Development Llc | Transfection sheets and methods of use |
| AU2013204327B2 (en) * | 2012-04-20 | 2016-09-01 | Aviagen | Cell transfection method |
| EP2911650B1 (en) | 2012-10-29 | 2019-09-04 | Agency For Science, Technology And Research | A novel reagent for gene-drug therapeutics |
-
2013
- 2013-10-29 EP EP13850878.3A patent/EP2911650B1/en active Active
- 2013-10-29 SG SG11201503020TA patent/SG11201503020TA/en unknown
- 2013-10-29 WO PCT/SG2013/000464 patent/WO2014070111A1/en active Application Filing
- 2013-10-29 DK DK13850878T patent/DK2911650T3/en active
- 2013-10-29 CN CN201380068711.6A patent/CN105101951B/en active Active
- 2013-10-29 US US14/439,330 patent/US10100331B2/en active Active
- 2013-10-29 JP JP2015539561A patent/JP6342910B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014070111A1 (en) | 2014-05-08 |
| US10100331B2 (en) | 2018-10-16 |
| EP2911650A1 (en) | 2015-09-02 |
| DK2911650T3 (en) | 2019-11-18 |
| CN105101951A (en) | 2015-11-25 |
| EP2911650A4 (en) | 2016-05-04 |
| US20150361449A1 (en) | 2015-12-17 |
| JP2016503290A (en) | 2016-02-04 |
| EP2911650B1 (en) | 2019-09-04 |
| CN105101951B (en) | 2021-08-03 |
| JP6342910B2 (en) | 2018-06-13 |
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