SG11201502163QA - Combinations and uses thereof - Google Patents

Combinations and uses thereof

Info

Publication number
SG11201502163QA
SG11201502163QA SG11201502163QA SG11201502163QA SG11201502163QA SG 11201502163Q A SG11201502163Q A SG 11201502163QA SG 11201502163Q A SG11201502163Q A SG 11201502163QA SG 11201502163Q A SG11201502163Q A SG 11201502163QA SG 11201502163Q A SG11201502163Q A SG 11201502163QA
Authority
SG
Singapore
Prior art keywords
combinations
Prior art date
Application number
SG11201502163QA
Inventor
Jan Endell
Lisa Rojkjaer
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of SG11201502163QA publication Critical patent/SG11201502163QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
SG11201502163QA 2012-09-25 2013-09-24 Combinations and uses thereof SG11201502163QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261705172P 2012-09-25 2012-09-25
US201361774595P 2013-03-08 2013-03-08
PCT/EP2013/069858 WO2014048921A1 (en) 2012-09-25 2013-09-24 Combinations and uses thereof

Publications (1)

Publication Number Publication Date
SG11201502163QA true SG11201502163QA (en) 2015-04-29

Family

ID=49237209

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201502163QA SG11201502163QA (en) 2012-09-25 2013-09-24 Combinations and uses thereof

Country Status (23)

Country Link
US (1) US9579378B2 (en)
EP (1) EP2900232B1 (en)
JP (1) JP6426093B2 (en)
KR (1) KR102171669B1 (en)
CN (1) CN104684552B (en)
AU (1) AU2013322806C1 (en)
BR (1) BR112015006731A2 (en)
CA (1) CA2885792C (en)
DK (1) DK2900232T3 (en)
ES (1) ES2658953T3 (en)
HK (1) HK1210949A1 (en)
HR (1) HRP20171964T1 (en)
HU (1) HUE036518T2 (en)
IL (1) IL237926B (en)
LT (1) LT2900232T (en)
MX (1) MX368288B (en)
NZ (1) NZ706147A (en)
PL (1) PL2900232T3 (en)
PT (1) PT2900232T (en)
RU (1) RU2650618C2 (en)
SG (1) SG11201502163QA (en)
WO (1) WO2014048921A1 (en)
ZA (1) ZA201501980B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5362359B2 (en) 2005-10-12 2013-12-11 モルフォシス アーゲー Generation and profiling of fully human HuCALGOLD-derived therapeutic antibodies specific for human CD38
US9732154B2 (en) 2014-02-28 2017-08-15 Janssen Biotech, Inc. Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
EP3191187B1 (en) * 2014-09-09 2021-07-28 Janssen Biotech, Inc. Combination therapies with anti-cd38 antibodies
IL307913A (en) 2014-12-04 2023-12-01 Janssen Biotech Inc Anti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of acute myeloid leukemiaanti-cd38 antibodies for treatment of ac
BR112017024877A2 (en) 2015-05-20 2019-09-17 Janssen Biotech, Inc. anti-cd38 antibody and its use in the treatment of light chain amyloidosis and other cd38 positive haematological malignancies
CR20170587A (en) 2015-06-22 2018-04-03 Janssen Biotech Inc Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors
US20170044265A1 (en) 2015-06-24 2017-02-16 Janssen Biotech, Inc. Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38
US10781261B2 (en) 2015-11-03 2020-09-22 Janssen Biotech, Inc. Subcutaneous formulations of anti-CD38 antibodies and their uses
CN108472369A (en) 2015-11-03 2018-08-31 詹森生物科技公司 The subcutaneous preparations and application thereof of 8 antibody of AntiCD3 McAb
CN108699161B (en) * 2016-03-04 2022-06-03 莫佛塞斯公司 Clinical assessment of M-protein response in multiple myeloma
EP3421494A1 (en) * 2017-06-29 2019-01-02 Sanofi Use of isatuximab in combination with an anti-pd-1 antibody
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. Multispecific molecules that bind to bcma and uses thereof
US11618787B2 (en) 2017-10-31 2023-04-04 Janssen Biotech, Inc. Methods of treating high risk multiple myeloma

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164788A1 (en) 1994-12-02 2002-11-07 The Wellcome Foundation Limited Humanized antibodies to CD38
CA2329940A1 (en) 1998-06-05 1999-12-09 Mayo Foundation For Medical Education And Research Use of genetically engineered antibodies to cd38 to treat multiple myeloma
US7223397B1 (en) 1999-01-07 2007-05-29 Research Development Foundation Potentiation of anti-CD38-Immunotoxin cytotoxicity
EP1174440A1 (en) 2000-07-19 2002-01-23 U-BISys B.V. A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment
ES2307832T3 (en) 2001-12-03 2008-12-01 Amgen Fremont Inc. ANTIBODY CLASSIFICATION BASED ON THE CHARACTERISTICS OF UNION.
ES2541436T3 (en) 2004-02-06 2015-07-20 Morphosys Ag Human anti-CD38 antibodies and uses for them
RS59399B1 (en) 2005-03-23 2019-11-29 Genmab As Antibodies against cd38 for treatment of multiple myeloma
EP2799451A1 (en) 2005-05-24 2014-11-05 MorphoSys AG Generation and profiling of fully human HuCAL GOLD®-derived therapeutic antibodies specific for human CD38
JP5362359B2 (en) 2005-10-12 2013-12-11 モルフォシス アーゲー Generation and profiling of fully human HuCALGOLD-derived therapeutic antibodies specific for human CD38
LT2081595T (en) 2006-09-26 2019-07-10 Genmab A/S Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
EP1914242A1 (en) 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
EP2191842A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cytarabine
EP2191841A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine
EP2191840A1 (en) * 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan
EP2191843A1 (en) 2008-11-28 2010-06-02 Sanofi-Aventis Antitumor combinations containing antibodies recognizing specifically CD38 and cyclophosphamide
EP3613774A1 (en) * 2010-06-09 2020-02-26 Genmab A/S Antibodies against human cd38
DK2621531T3 (en) * 2010-09-27 2017-02-27 Morphosys Ag ANTI-CD38 ANTIBODY AND LENALIDOMIDE OR BORTEZOMIB FOR TREATMENT OF MULTIPLE MYELOM AND NHL
UA112170C2 (en) 2010-12-10 2016-08-10 Санофі ANTI-TUMOR COMBINATION CONTAINING AN ANTIBODY SPECIFICALLY RECOGNIZING CD38 AND BORTESOMB
JOP20210044A1 (en) 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co Anti-cd38 antibodies
US20140221319A1 (en) 2011-06-29 2014-08-07 Mayo Foundation For Medical Education And Research Small Molecule CD38 Inhibitors and Methods of Using Same
RU2723937C2 (en) 2013-03-13 2020-06-18 Санофи Compositions comprising cd38 antibodies and carfilzomib
AU2013388126B2 (en) 2013-04-29 2019-03-07 Teva Pharmaceuticals Australia Pty Ltd. Anti-CD38 antibodies and fusions to attenuated interferon alpha-2b

Also Published As

Publication number Publication date
HK1210949A1 (en) 2016-05-13
AU2013322806C1 (en) 2018-03-08
CN104684552A (en) 2015-06-03
PL2900232T3 (en) 2018-05-30
KR102171669B1 (en) 2020-10-30
BR112015006731A2 (en) 2017-07-04
PT2900232T (en) 2018-02-09
EP2900232B1 (en) 2017-11-15
MX368288B (en) 2019-09-27
RU2650618C2 (en) 2018-04-16
US20150238603A1 (en) 2015-08-27
AU2013322806B2 (en) 2017-11-30
CA2885792A1 (en) 2014-04-03
IL237926A0 (en) 2015-05-31
MX2015003589A (en) 2015-08-12
ES2658953T3 (en) 2018-03-13
WO2014048921A1 (en) 2014-04-03
HUE036518T2 (en) 2018-07-30
HRP20171964T1 (en) 2018-02-23
DK2900232T3 (en) 2018-02-05
CN104684552B (en) 2018-08-07
JP2015530399A (en) 2015-10-15
JP6426093B2 (en) 2018-11-28
KR20150090030A (en) 2015-08-05
LT2900232T (en) 2018-02-26
ZA201501980B (en) 2017-11-29
EP2900232A1 (en) 2015-08-05
US9579378B2 (en) 2017-02-28
NZ706147A (en) 2018-10-26
CA2885792C (en) 2021-09-28
IL237926B (en) 2020-04-30
RU2015110981A (en) 2016-11-20
AU2013322806A1 (en) 2015-04-09

Similar Documents

Publication Publication Date Title
IL269045B (en) Aptamers and uses thereof
HK1199023A1 (en) Substituted benzothienylpyrrolotriazines and uses thereof
HK1202545A1 (en) New diazaspirocycloalkane and azaspirocycloalkane
HK1200822A1 (en) Substituted dipyridylamines and uses thereof
HK1203493A1 (en) Substituted azabicycles and use thereof
IL237309A0 (en) Benzocyclooctyne compounds and uses thereof
HK1210949A1 (en) Combinations and uses thereof
HK1203198A1 (en) Substituted phenylimidazopyrazoles and use thereof
HK1210809A1 (en) Beta-hexosyl-transferases and uses thereof
EP2938415A4 (en) Materials and methods
PL2882708T3 (en) New compounds and uses thereof
HK1207154A1 (en) C1q-adiponectin complex and use thereof c1q-
RS56379B1 (en) Dermo-protective and dermo-balancing composition
GB201222541D0 (en) Kiddibidet and pottibidet
IL218974A0 (en) Conaction bitwen coutch and playels
GB201202021D0 (en) Co-sleeper and breastfeeder
GB201222342D0 (en) Compounds and uses thereof
GB201214749D0 (en) Compounds and their uses
EP2922862A4 (en) Complex-formation-modulating agents and uses therefor
GB201215414D0 (en) Composition and use
GB201206973D0 (en) New compounds and uses
GB201207075D0 (en) New compounds and uses
GB201206055D0 (en) New compounds and uses