SG11201501954SA - Low molecular weight branched polyamines for delivery of biologically active materials - Google Patents

Low molecular weight branched polyamines for delivery of biologically active materials

Info

Publication number
SG11201501954SA
SG11201501954SA SG11201501954SA SG11201501954SA SG11201501954SA SG 11201501954S A SG11201501954S A SG 11201501954SA SG 11201501954S A SG11201501954S A SG 11201501954SA SG 11201501954S A SG11201501954S A SG 11201501954SA SG 11201501954S A SG11201501954S A SG 11201501954SA
Authority
SG
Singapore
Prior art keywords
delivery
molecular weight
low molecular
biologically active
active materials
Prior art date
Application number
SG11201501954SA
Inventor
Wei Cheng
Daniel J Coady
Amanda C Engler
James L Hedrick
Pei Yun Teo
Chuan Yang
Yi Yan Yang
Original Assignee
Ibm
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ibm, Agency Science Tech & Res filed Critical Ibm
Publication of SG11201501954SA publication Critical patent/SG11201501954SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
SG11201501954SA 2012-09-13 2013-09-04 Low molecular weight branched polyamines for delivery of biologically active materials SG11201501954SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/613,353 US9109087B2 (en) 2012-09-13 2012-09-13 Low molecular weight branched polyamines for delivery of biologically active materials
PCT/US2013/057978 WO2014042922A1 (en) 2012-09-13 2013-09-04 Low molecular weight branched polyamines for delivery of biologically active materials

Publications (1)

Publication Number Publication Date
SG11201501954SA true SG11201501954SA (en) 2015-05-28

Family

ID=50233651

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501954SA SG11201501954SA (en) 2012-09-13 2013-09-04 Low molecular weight branched polyamines for delivery of biologically active materials

Country Status (6)

Country Link
US (1) US9109087B2 (en)
EP (1) EP2895527A4 (en)
JP (1) JP6276274B2 (en)
CN (1) CN104755534B (en)
SG (1) SG11201501954SA (en)
WO (1) WO2014042922A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703197B2 (en) * 2012-09-13 2014-04-22 International Business Machines Corporation Branched polyamines for delivery of biologically active materials
US9682100B2 (en) 2015-01-26 2017-06-20 International Business Machines Corporation Cationic polyamines for treatment of viruses
WO2017120536A1 (en) * 2016-01-08 2017-07-13 Apg Therapeutics, Inc. Polyethylenimine (pei)-polypeptide conjugates and methods of use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142474A1 (en) * 2000-09-14 2004-07-22 Expression Genetics, Inc. Novel cationic lipopolymer as a biocompatible gene delivery agent
US6696038B1 (en) * 2000-09-14 2004-02-24 Expression Genetics, Inc. Cationic lipopolymer as biocompatible gene delivery agent
US20050059068A1 (en) 2001-05-23 2005-03-17 Stratagene California Compositions and methods using dendrimer-treated microassays
US20030215395A1 (en) * 2002-05-14 2003-11-20 Lei Yu Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier
US7358223B2 (en) * 2004-10-04 2008-04-15 Nitto Denko Corporation Biodegradable cationic polymers
US20070231392A1 (en) 2006-01-23 2007-10-04 Ernst Wagner CHEMICALLY MODIFIED POLYCATION POLYMER FOR siRNA DELIVERY
CN101437544A (en) * 2006-01-23 2009-05-20 艾博特公司 Chemically modified polycation polymer for siRNA delivery
US20100075420A1 (en) 2008-03-14 2010-03-25 Anita Saraf Novel Gene Delivery Vectors for Human Mesenchymal Stem Cells
WO2009114854A1 (en) * 2008-03-14 2009-09-17 Egen, Inc. Biodegradable cross-linked branched poly (alkylene imines)
US8344116B2 (en) * 2008-03-17 2013-01-01 Case Western Reserve University Polymers and complexes for delivery of nucleic acids to intracellular targets
US8450529B2 (en) 2008-10-02 2013-05-28 Covidien Lp Branched polyamines and formulations thereof for use in medical devices
US8143369B2 (en) * 2009-06-02 2012-03-27 International Business Machines Corporation Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
CN101575416A (en) 2009-06-15 2009-11-11 中国科学院长春应用化学研究所 Multi-arm polyamino acid (ester) grafted polyethyleneimine copolymer, preparation method and application in gene delivery
CN101638484A (en) 2009-08-24 2010-02-03 中国科学院长春应用化学研究所 Polyethylene glycol monomethyl ether-poly 2-methyl-carboxyl propylene carbonate graft polyethyleneimine copolymer, preparation method thereof and application thereof
US20110151566A1 (en) * 2009-12-23 2011-06-23 James Hedrick Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto
US8226985B2 (en) 2010-01-28 2012-07-24 International Business Machines Corporation Surface modified nanoparticles, methods of their preparation, and uses thereof for gene and drug delivery

Also Published As

Publication number Publication date
JP6276274B2 (en) 2018-02-07
EP2895527A4 (en) 2016-04-20
US20140073048A1 (en) 2014-03-13
CN104755534A (en) 2015-07-01
JP2015531421A (en) 2015-11-02
WO2014042922A1 (en) 2014-03-20
US9109087B2 (en) 2015-08-18
EP2895527A1 (en) 2015-07-22
CN104755534B (en) 2017-03-08

Similar Documents

Publication Publication Date Title
GB201503188D0 (en) Branched polyamines for delivery of biologically active materials
HK1208374A1 (en) Biodegradable drug delivery for hydrophobic compositions
GB2479953B (en) Drug delivery device
PL2654864T3 (en) System for drug delivery
HK1201089A1 (en) Functionalized nanoparticles for intracellular delivery of biologically active molecules
EP3824925C0 (en) Drug delivery device
HUE042850T2 (en) Compositions for drug delivery
EP2665431C0 (en) Drug delivery technology
PL2616133T3 (en) Devices for transdermal drug delivery
EP2794879A4 (en) Compositions and methods for the delivery of biologically active rnas
IL227352A0 (en) Ocular drug delivery system
HRP20181316T1 (en) Drug delivery technology
ZA201309156B (en) Drug delivery system
HK1185573A1 (en) Composition for active principles delivery by implant devices
SG11201501917SA (en) Composite hydrogels for delivery of biologically active materials
HK1189156A1 (en) Transdermal delivery system containing galantamine or salts thereof
SG11201501954SA (en) Low molecular weight branched polyamines for delivery of biologically active materials
GB201110632D0 (en) Drug delivery formulations
EP2870883A4 (en) Composition containing biologically active substance
EP2626055A4 (en) Drug delivery device
GB201018750D0 (en) Drug delivery system
GB201005639D0 (en) Drug delivery formulations