SG11201501623PA - Recombinant particle based vaccines against human cytomegalovirus infection - Google Patents

Recombinant particle based vaccines against human cytomegalovirus infection

Info

Publication number
SG11201501623PA
SG11201501623PA SG11201501623PA SG11201501623PA SG11201501623PA SG 11201501623P A SG11201501623P A SG 11201501623PA SG 11201501623P A SG11201501623P A SG 11201501623PA SG 11201501623P A SG11201501623P A SG 11201501623PA SG 11201501623P A SG11201501623P A SG 11201501623PA
Authority
SG
Singapore
Prior art keywords
against human
human cytomegalovirus
vaccines against
based vaccines
particle based
Prior art date
Application number
SG11201501623PA
Inventor
Sabine Wellnitz
Corinne John
Christian Schaub
Original Assignee
Redvax Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Redvax Gmbh filed Critical Redvax Gmbh
Publication of SG11201501623PA publication Critical patent/SG11201501623PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16123Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
SG11201501623PA 2012-10-30 2013-10-30 Recombinant particle based vaccines against human cytomegalovirus infection SG11201501623PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12190652 2012-10-30
PCT/EP2013/072717 WO2014068001A1 (en) 2012-10-30 2013-10-30 Recombinant particle based vaccines against human cytomegalovirus infection

Publications (1)

Publication Number Publication Date
SG11201501623PA true SG11201501623PA (en) 2015-05-28

Family

ID=47073362

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501623PA SG11201501623PA (en) 2012-10-30 2013-10-30 Recombinant particle based vaccines against human cytomegalovirus infection

Country Status (16)

Country Link
US (1) US20150359879A1 (en)
EP (2) EP3269388A1 (en)
JP (1) JP6294890B2 (en)
KR (1) KR20150076244A (en)
CN (1) CN104853772A (en)
AU (1) AU2013340820A1 (en)
BR (1) BR112015008930A2 (en)
CA (1) CA2885145A1 (en)
ES (1) ES2608637T3 (en)
HK (1) HK1213185A1 (en)
IL (1) IL237793A0 (en)
MX (1) MX2015005505A (en)
PH (1) PH12015500931A1 (en)
RU (1) RU2015121828A (en)
SG (1) SG11201501623PA (en)
WO (1) WO2014068001A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
EP3134117A1 (en) * 2014-04-23 2017-03-01 Institute for Research in Biomedicine Human cytomegalovirus vaccine compositions and method of producing the same
WO2015165480A1 (en) * 2014-04-30 2015-11-05 Institute For Research In Biomedicine Human cytomegalovirus vaccine compositions and method of producing the same
TW201609792A (en) * 2014-05-08 2016-03-16 輝瑞大藥廠 Means and methods for treating CMV
US10428118B2 (en) * 2014-07-16 2019-10-01 Oregon Health & Science University Human cytomegalovirus comprising exogenous antigens
US10010607B2 (en) 2014-09-16 2018-07-03 Institut Curie Method for preparing viral particles with cyclic dinucleotide and use of said particles for inducing immune response
EP3048114A1 (en) * 2015-01-22 2016-07-27 Novartis AG Cytomegalovirus antigens and uses thereof
WO2017070613A1 (en) 2015-10-22 2017-04-27 Modernatx, Inc. Human cytomegalovirus vaccine
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
EP3770265B1 (en) 2016-03-16 2023-10-11 Institut Curie Method for preparing viral particles with cyclic dinucleotide and use of said particles for treating cancer
AU2017345766A1 (en) 2016-10-21 2019-05-16 Modernatx, Inc. Human cytomegalovirus vaccine
EP3573649A4 (en) * 2017-01-27 2020-12-30 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Vaccine compositions of herpesvirus envelope protein combinations to induce immune response
CA3060019A1 (en) 2017-04-19 2018-10-25 Glaxosmithkline Biologicals Sa Modified cytomegalovirus proteins and stabilized complexes
US11524069B2 (en) * 2017-09-13 2022-12-13 Sanofi Pasteur Human cytomegalovirus immunogenic composition
FR3077490B1 (en) * 2018-02-02 2022-11-11 Univ Franche Comte NEW VACCINE COMPOSITIONS FOR FIGHT AGAINST BREAST CANCER, AND METHOD FOR PREPARATION
EP3762025A4 (en) * 2018-03-09 2021-12-01 The Regents of the University of California Cmv vectors and uses thereof
WO2019216929A1 (en) * 2018-05-11 2019-11-14 City Of Hope Mva vectors for expressing multiple cytomegalovirus (cmv) antigens and use thereof
KR102018341B1 (en) * 2018-06-21 2019-09-04 성균관대학교산학협력단 A pharmaceutical composition for preventing or treating cancer comprising RNF170 and pUL50 as an active ingredient
CA3116175A1 (en) 2018-10-17 2020-04-23 Glaxosmithkline Biologicals Sa Modified cytomegalovirus proteins and stabilized complexes
US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
US20230266320A1 (en) * 2019-11-26 2023-08-24 Merck Sharp & Dohme Llc Method for detecting cytomegalovirus (cmv) and measuring and quantifying pentameric complex using an indirect sandwich elisa
TWI810589B (en) 2020-06-21 2023-08-01 美商輝瑞股份有限公司 Human cytomegalovirus gb polypeptide
US11406703B2 (en) 2020-08-25 2022-08-09 Modernatx, Inc. Human cytomegalovirus vaccine
WO2023223255A1 (en) 2022-05-20 2023-11-23 Glaxosmithkline Biologicals Sa Modified varicella zoster virus glycoprotein e proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5990085A (en) 1998-05-04 1999-11-23 Michigan State University Inhibin-HBc fusion protein
BRPI0512042B8 (en) 2004-06-16 2021-05-25 Glaxosmithkline Biologicals Sa immunogenic composition, vaccine, use of a composition or vaccine, method for producing an immunogenic composition, and, use of vlps or capsomeres of hpv 16 and 18 with vlps or capsomeres of at least one other hpv of the cancer-causing type
CA2682700A1 (en) * 2007-05-11 2008-11-20 Vakzine Projekt Management Gmbh Composition containing hcmv particles
EP2303319B1 (en) * 2008-06-20 2016-10-05 Duke University Compositions, methods and kits for eliciting an immune response
CA2760524C (en) * 2009-05-01 2017-09-12 Redbiotec Ag Recombinant virus-like particles encoded by multi-gene vector
GB0907935D0 (en) * 2009-05-08 2009-06-24 Henderson Morley Plc Vaccines
ES2656050T3 (en) * 2011-07-06 2018-02-22 Glaxosmithkline Biologicals Sa Immunogenic combination compositions and uses thereof
KR102301463B1 (en) * 2011-11-11 2021-09-14 배리에이션 바이오테크놀로지스 아이엔씨. Compositions and methods for treatment of cytomegalovirus

Also Published As

Publication number Publication date
EP3269388A1 (en) 2018-01-17
JP2015536937A (en) 2015-12-24
BR112015008930A2 (en) 2017-11-21
IL237793A0 (en) 2015-05-31
EP2914284A1 (en) 2015-09-09
US20150359879A1 (en) 2015-12-17
AU2013340820A1 (en) 2015-03-19
ES2608637T3 (en) 2017-04-12
HK1213185A1 (en) 2016-06-30
CN104853772A (en) 2015-08-19
WO2014068001A1 (en) 2014-05-08
CA2885145A1 (en) 2014-05-08
PH12015500931A1 (en) 2015-06-29
MX2015005505A (en) 2016-01-08
KR20150076244A (en) 2015-07-06
RU2015121828A (en) 2016-12-20
EP2914284B1 (en) 2016-09-21
JP6294890B2 (en) 2018-03-14

Similar Documents

Publication Publication Date Title
HK1213185A1 (en) Recombinant particle based vaccines against human cytomegalovirus infection
IL261204A (en) Influenza virus vaccines and uses thereof
HK1207967A1 (en) Vaccine
HK1209439A1 (en) Interleukin-10 fusion proteins and uses thereof -10
EP2614072A4 (en) Human cytomegalovirus vaccine
EP2830692A4 (en) Patient interface
EP2820033A4 (en) Interleukin-10 polypeptide conjugates and their uses
EP2806891A4 (en) Parainfluenza virus 5 based vaccines
PL2935313T3 (en) Vaccines against hepatitis b virus
EP2909238A4 (en) Improved human herpesvirus immunotherapy
HK1204479A1 (en) Expression and secretion system
HK1210475A1 (en) Herpes simplex virus vaccine
EP3054994A4 (en) Human papilloma virus therapeutic vaccine
HK1212730A1 (en) Ube2t peptides and vaccines containing the same ube2t
IL229956B (en) Mphosphi peptides and vaccines including the same
EP2931176A4 (en) Medical sling
EP2678043A4 (en) Recombinant mumps virus vaccine
EP2919806A4 (en) Gonorrheal mtre peptides and vaccines
EP2822599A4 (en) Vaccine formulation
HK1201283A1 (en) Influenza c virus and vaccine
EP2839840A4 (en) Recombinant trivalent vaccine against human influenza
EP2891497A4 (en) Dna vaccine containing vegf-specific epitope and/or angiopoietin-2-specific epitope
GB201215184D0 (en) Therapeutic virus
HUE051050T2 (en) Recombinant human igm-antibody effective against cancer cells
EP2862873A4 (en) IgE PEPTIDE VACCINE