SG11201501415RA - Orally administered medical composition - Google Patents

Orally administered medical composition

Info

Publication number
SG11201501415RA
SG11201501415RA SG11201501415RA SG11201501415RA SG11201501415RA SG 11201501415R A SG11201501415R A SG 11201501415RA SG 11201501415R A SG11201501415R A SG 11201501415RA SG 11201501415R A SG11201501415R A SG 11201501415RA SG 11201501415R A SG11201501415R A SG 11201501415RA
Authority
SG
Singapore
Prior art keywords
orally administered
medical composition
administered medical
composition
orally
Prior art date
Application number
SG11201501415RA
Inventor
Yuuki Tsutsui
Hiroyasu Toyota
Tadashi Hakomori
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of SG11201501415RA publication Critical patent/SG11201501415RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
SG11201501415RA 2012-08-31 2013-08-30 Orally administered medical composition SG11201501415RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012191833 2012-08-31
PCT/JP2013/073351 WO2014034860A1 (en) 2012-08-31 2013-08-30 Orally administered medical composition

Publications (1)

Publication Number Publication Date
SG11201501415RA true SG11201501415RA (en) 2015-05-28

Family

ID=50183665

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201501415RA SG11201501415RA (en) 2012-08-31 2013-08-30 Orally administered medical composition

Country Status (17)

Country Link
US (1) US20150306090A1 (en)
EP (1) EP2891493A4 (en)
JP (1) JPWO2014034860A1 (en)
KR (1) KR20150045500A (en)
CN (1) CN104602693A (en)
AU (1) AU2013309922A1 (en)
BR (1) BR112015004244A2 (en)
CA (1) CA2883270A1 (en)
EA (1) EA201590449A1 (en)
HK (1) HK1208801A1 (en)
IL (1) IL237423A0 (en)
MX (1) MX2015002633A (en)
PH (1) PH12015500313A1 (en)
SG (1) SG11201501415RA (en)
TW (1) TW201424772A (en)
WO (1) WO2014034860A1 (en)
ZA (1) ZA201501977B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
JP2017078023A (en) * 2014-02-28 2017-04-27 アステラス製薬株式会社 Pharmaceutical composition for oral administration
US9956194B2 (en) 2014-12-03 2018-05-01 Velicept Therapeutics, Inc. Compositions and methods of using modified release solabegron for lower urinary tract symptoms
EP3365321B1 (en) 2015-10-23 2023-12-13 B3AR Therapeutics, Inc. Solabegron zwitterion and uses thereof
WO2017186593A1 (en) 2016-04-25 2017-11-02 Synthon B.V. Tablets comprising mirabegron and solifenacin
US10543174B2 (en) 2016-04-25 2020-01-28 Synthon B.V. Modified release tablet composition comprising mirabegron
CN107397733B (en) * 2016-05-20 2020-02-07 山东威智百科药业有限公司 Mirabegron sustained release tablet and preparation method thereof
WO2017210696A1 (en) * 2016-06-03 2017-12-07 Velicept Therapeutics, Inc. Dosing regimens for beta-3 adrenoceptor agonists and anti-muscarinic agents for the treatment and prevention of lower urinary tract symptoms and overactive bladder
CN106361715A (en) * 2016-09-02 2017-02-01 迪沙药业集团有限公司 Mirabegron composition
KR102051132B1 (en) * 2017-03-17 2019-12-02 주식회사 종근당 Pharmaceutical composition for controlled release comprising Mirabegron or its salts
KR101877834B1 (en) * 2017-04-27 2018-07-12 주식회사 다산제약 Novel salts of mirabegron and manufacturing method thereof
KR20170088783A (en) * 2017-07-07 2017-08-02 지엘팜텍주식회사 Wetgranulation composition containing mirabegron
WO2019013583A2 (en) * 2017-07-14 2019-01-17 주식회사 대웅제약 Pharmaceutical preparation and preparation method therefor
KR101937713B1 (en) 2017-07-14 2019-01-14 주식회사 대웅제약 Pharmaceutical formulation and preparation method for the same
US10478399B2 (en) 2017-10-12 2019-11-19 Synthon B.V. Modified release tablet composition comprising mirabegron
KR102018495B1 (en) * 2018-03-13 2019-09-05 충북대학교 산학협력단 Sustained-release bilayer tablets for the treatment of overactive bladder And method for manufacturing the same
KR102371567B1 (en) * 2018-04-06 2022-03-07 한미약품 주식회사 Controlled Release Pharmaceutical Composition comprising Mirabegron
WO2020097328A1 (en) * 2018-11-07 2020-05-14 Velicept Therapeutics, Inc Fixed dose pharmaceutical compositions for treating overactive bladder and related conditions
KR102062791B1 (en) * 2019-02-26 2020-01-06 신일제약 주식회사 Pharmaceutical formulation for controlled release containing mirabegron or pharmaceutically acceptable salts thereof as an active ingredient
US20210353546A1 (en) * 2020-05-12 2021-11-18 Jubilant Pharma Holdings Inc. Dual release pharmaceutical compositions comprising the combination of a beta-3 adrenoreceptor agonist and a muscarinic receptor antagonist
EP4159199A1 (en) 2021-09-29 2023-04-05 Lotus Pharmaceutical Co., Ltd. Combined formulation of mirabegron and solifenacin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2005012I1 (en) 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin and pharmaceutically acceptable salts thereof
DE69802832T2 (en) * 1997-10-03 2002-06-20 Warner Lambert Co PRESSED NITROGLYCERIN TABLETS AND METHOD FOR THE PRODUCTION THEREOF
ID23989A (en) 1997-10-17 2000-06-14 Yamanouchi Pharma Co Ltd THE AMIDA DOWNS OR THE SALT
US7342117B2 (en) 2001-10-30 2008-03-11 Astellas Pharma Inc. α-form or β-form crystal of acetanilide derivative
CA2503570C (en) 2002-11-07 2011-04-19 Yamanouchi Pharmaceutical Co., Ltd. Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient
SI2216021T1 (en) 2007-11-02 2013-01-31 Astellas Pharma Inc. Pharmaceutical composition for treating overactive bladder
TWI478712B (en) 2008-09-30 2015-04-01 Astellas Pharma Inc Pharmaceutical composition for modified release
AU2010211725C1 (en) * 2009-02-04 2014-10-16 Astellas Pharma Inc. Pharmaceutical composition for oral administration
SG10201506076TA (en) * 2010-08-03 2015-09-29 Altherx Inc Combinations of beta - 3 adrenergic receptor agonists and muscarinic receptor antagonists for treating overactive bladder
TWI612975B (en) * 2012-03-02 2018-02-01 安斯泰來製藥股份有限公司 Quickly disintegrating tablet

Also Published As

Publication number Publication date
CN104602693A (en) 2015-05-06
ZA201501977B (en) 2016-07-27
EP2891493A1 (en) 2015-07-08
US20150306090A1 (en) 2015-10-29
KR20150045500A (en) 2015-04-28
EA201590449A1 (en) 2015-06-30
AU2013309922A1 (en) 2015-04-09
CA2883270A1 (en) 2014-03-06
IL237423A0 (en) 2015-04-30
EP2891493A4 (en) 2016-05-18
PH12015500313A1 (en) 2015-04-20
WO2014034860A1 (en) 2014-03-06
TW201424772A (en) 2014-07-01
HK1208801A1 (en) 2016-03-18
BR112015004244A2 (en) 2017-07-04
JPWO2014034860A1 (en) 2016-08-08
MX2015002633A (en) 2015-06-24

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