SG11201407375XA - Biosynthetic pathways, recombinant cells, and methods - Google Patents

Biosynthetic pathways, recombinant cells, and methods

Info

Publication number
SG11201407375XA
SG11201407375XA SG11201407375XA SG11201407375XA SG11201407375XA SG 11201407375X A SG11201407375X A SG 11201407375XA SG 11201407375X A SG11201407375X A SG 11201407375XA SG 11201407375X A SG11201407375X A SG 11201407375XA SG 11201407375X A SG11201407375X A SG 11201407375XA
Authority
SG
Singapore
Prior art keywords
methods
international
recombinant cells
cells
minneapolis
Prior art date
Application number
SG11201407375XA
Inventor
Kechun Zhang
Yogesh K Dhande
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of SG11201407375XA publication Critical patent/SG11201407375XA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 November 2013 (14.11.2013) WIPOIPCT (10) International Publication Number WO 2013/169350 A1 (51) International Patent Classification: C12N 9/02 (2006.01) C12N15/52 (2006.01) C12N9/88 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/US2013/030719 13 March 2013 (13.03.2013) English (30) Priority Data: 61/645,900 11 May 2012 (11.05.2012) English US (71) Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA [US/US]; Office for Technology Commer­ cialization, 1000 Westgate Drive, Suite 160, Saint Paul, MN 55114-8658 (US). (72) Inventors; and (71) Applicants ZHANG, Kechun : [CN/US]; 1051 5th Street SE, Minneapolis, MN 55414 (US). DHANDE, Yogesh, K. [IN/US]; 519 3rd Avenue SE, Apt. 208, Minneapolis, MN 55414 (US). (74) Agent: GRAM, Christopher, D.; Mueting, Raasch & Gebhardt, P.A., P.O. Box 581336, Minneapolis, MN 55458-1336 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a)) © m o\ i-H o CJ (54) Title: BIOSYNTHETIC PATHWAYS, RECOMBINANT CELLS, AND METHODS (57) Abstract: This disclosure describes, generally, recombinant cells modified to exhibit increased biosynthesis of pentanoic acid, methods of making such recombinant cells, and methods of inducing the cells to produce pentanoic acid. This disclosure also de - scribes, generally, recombinant cells modified to exhibit increased biosynthesis of 2-methylbutyric acid, methods of making such re­ combinant cells, and methods of inducing the cells produce to 2-methylbutyric acid.
SG11201407375XA 2012-05-11 2013-03-13 Biosynthetic pathways, recombinant cells, and methods SG11201407375XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261645900P 2012-05-11 2012-05-11
PCT/US2013/030719 WO2013169350A1 (en) 2012-05-11 2013-03-13 Biosynthetic pathways, recombinant cells, and methods

Publications (1)

Publication Number Publication Date
SG11201407375XA true SG11201407375XA (en) 2014-12-30

Family

ID=48050901

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201407375XA SG11201407375XA (en) 2012-05-11 2013-03-13 Biosynthetic pathways, recombinant cells, and methods

Country Status (8)

Country Link
US (1) US20150132813A1 (en)
EP (1) EP2847325A1 (en)
JP (1) JP2015515866A (en)
KR (1) KR20150014952A (en)
CN (1) CN104520426A (en)
AU (1) AU2013260096A1 (en)
SG (1) SG11201407375XA (en)
WO (1) WO2013169350A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110331173B (en) * 2019-07-29 2020-07-17 湖北大学 Application of phenylpyruvic acid decarboxylase mutant M538A in production of phenethyl alcohol through biological fermentation
EP4034668B1 (en) * 2019-09-25 2024-04-17 Ajinomoto Co., Inc. Method for producing 2-methyl-butyric acid by bacterial fermentation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
JP2009000046A (en) * 2007-06-21 2009-01-08 Hitachi Zosen Corp Gene encoding enzyme involved in mevalonic acid pathway of eucommia ulmoides oliver

Also Published As

Publication number Publication date
CN104520426A (en) 2015-04-15
KR20150014952A (en) 2015-02-09
US20150132813A1 (en) 2015-05-14
EP2847325A1 (en) 2015-03-18
JP2015515866A (en) 2015-06-04
WO2013169350A1 (en) 2013-11-14
AU2013260096A1 (en) 2014-11-27

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