SG11201404349YA - Detection of target nucleic acid sequence by pto cleavage and extension-dependent signaling oligonucleotide hybridization assay - Google Patents
Detection of target nucleic acid sequence by pto cleavage and extension-dependent signaling oligonucleotide hybridization assayInfo
- Publication number
- SG11201404349YA SG11201404349YA SG11201404349YA SG11201404349YA SG11201404349YA SG 11201404349Y A SG11201404349Y A SG 11201404349YA SG 11201404349Y A SG11201404349Y A SG 11201404349YA SG 11201404349Y A SG11201404349Y A SG 11201404349YA SG 11201404349Y A SG11201404349Y A SG 11201404349YA
- Authority
- SG
- Singapore
- Prior art keywords
- extension
- detection
- nucleic acid
- acid sequence
- target nucleic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120010681 | 2012-02-02 | ||
| KR1020120028429A KR20130101952A (en) | 2012-02-02 | 2012-03-20 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent hybridization |
| PCT/KR2012/005281 WO2013115442A1 (en) | 2012-02-02 | 2012-07-03 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent signaling oligonucleotide hybridization assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201404349YA true SG11201404349YA (en) | 2014-08-28 |
Family
ID=49451920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201404349YA SG11201404349YA (en) | 2012-02-02 | 2012-07-03 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent signaling oligonucleotide hybridization assay |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9868980B2 (en) |
| EP (1) | EP2809797B1 (en) |
| JP (1) | JP6005180B2 (en) |
| KR (2) | KR20130101952A (en) |
| CN (2) | CN106011234B (en) |
| AU (2) | AU2012368436B2 (en) |
| BR (1) | BR112014018940B1 (en) |
| CA (1) | CA2862488C (en) |
| IL (1) | IL233773B (en) |
| MX (1) | MX361903B (en) |
| NO (1) | NO20140948A1 (en) |
| RU (1) | RU2608501C2 (en) |
| SG (1) | SG11201404349YA (en) |
| WO (1) | WO2013115442A1 (en) |
| ZA (1) | ZA201405463B (en) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MX2017015093A (en) | 2011-01-11 | 2023-03-10 | Seegene Inc | Detection of target nucleic acid sequences by pto cleavage and extension assay. |
| KR101569479B1 (en) | 2011-03-29 | 2015-11-16 | 주식회사 씨젠 | Detection of Target Nucleic Acid Sequence by PTO Cleavage and Extension-Dependent Cleavage |
| US9850524B2 (en) | 2011-05-04 | 2017-12-26 | Seegene, Inc. | Detection of target nucleic acid sequences by PO cleavage and hybridization |
| KR20130101952A (en) | 2012-02-02 | 2013-09-16 | 주식회사 씨젠 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent hybridization |
| JP5976849B2 (en) | 2012-03-05 | 2016-08-24 | シージーン アイエヌシー | Detection of nucleotide mutations in target nucleic acid sequences by PTO cleavage and extension assays {Detection of Nucleotide Variation on Target Nucleic Acid Sequence PTO Cleavage and Extension Assay} |
| EP2839031B1 (en) * | 2012-04-19 | 2017-03-29 | Seegene, Inc. | Detection of target nucleic acid sequence by pto cleavage and extension-dependent signaling oligonucleotide cleavage |
| KR101572682B1 (en) | 2013-05-30 | 2015-11-30 | 케이맥(주) | Real time quantitative and qualitative analizing method |
| WO2015147370A1 (en) | 2014-03-28 | 2015-10-01 | Seegene, Inc. | Detection of target nucleic acid sequences using different detection temperatures |
| JP6734851B2 (en) | 2014-12-09 | 2020-08-05 | シージーン アイエヌシー | Discrimination of signals for target nucleic acid sequences |
| US20180355413A1 (en) | 2014-12-22 | 2018-12-13 | Anapa Biotech A/S | Dual quenching assay for multiplex detection of target nucleic acids |
| WO2017086762A1 (en) | 2015-11-20 | 2017-05-26 | Seegene, Inc. | Method for calibrating a data set of a target analyte |
| WO2017135756A1 (en) | 2016-02-05 | 2017-08-10 | Seegene, Inc. | Method for reducing noise level of data set for a target analyte |
| KR101961642B1 (en) * | 2016-04-25 | 2019-03-25 | (주)진매트릭스 | A method for detecting target nucleic acid sequence using cleaved complementary tag fragment and a composition therefor |
| US11066704B2 (en) | 2016-06-10 | 2021-07-20 | Seegene, Inc. | Methods for preparing tagging oligonucleotides |
| KR102264865B1 (en) | 2016-06-30 | 2021-06-14 | 주식회사 씨젠 | Fluorescence-detecting device for analysis of reaction |
| EP3512959B1 (en) * | 2016-09-15 | 2021-08-11 | Roche Diagnostics GmbH | Methods for performing multiplexed pcr |
| KR102523355B1 (en) * | 2016-12-23 | 2023-04-20 | 알베르트-루드빅스-유니베르지텟 푸라이부르그 | 2-piece vector probe |
| IL267372B2 (en) | 2016-12-29 | 2024-02-01 | Seegene Inc | Method for reducing primer dimer formation and increasing amplification efficiency |
| KR102408564B1 (en) * | 2017-03-28 | 2022-06-14 | 주식회사 씨젠 | Analytical signal for determination of the presence of a target nucleic acid sequence |
| CN108823287B (en) * | 2017-04-28 | 2019-04-12 | 厦门大学 | A method of detection target nucleic acid sequence |
| WO2019045532A2 (en) | 2017-08-31 | 2019-03-07 | Seegene, Inc. | Evaluation of performance of components using a pair of dimer-forming primers |
| KR102345601B1 (en) * | 2017-09-29 | 2021-12-30 | 주식회사 씨젠 | Detection of target nucleic acid sequences by PTO cleavage and extension-dependent extension analysis |
| US20190112636A1 (en) * | 2017-10-16 | 2019-04-18 | ChromaCode, Inc. | Methods and compositions for nucleic acid detection |
| WO2019135567A1 (en) | 2018-01-05 | 2019-07-11 | Seegene, Inc. . | Method for determining the presence or absence of m. tuberculosis, m. bovis and m. bovis bcg in a sample |
| BR112020019755A2 (en) | 2018-04-20 | 2021-01-26 | Seegene, Inc. | method and apparatus for detecting a plurality of target nucleic acid sequences in the sample |
| KR20230031343A (en) * | 2020-06-30 | 2023-03-07 | 스피디엑스 피티와이 리미티드 | Multiplex detection of nucleic acids using mixed reporters |
| CN114250275B (en) * | 2020-09-22 | 2023-04-28 | 武汉艾米森生命科技有限公司 | Fluorescent quantitative PCR reaction system, PCR reaction kit and nucleic acid quantitative detection method |
| CN114622000B (en) * | 2020-12-14 | 2024-05-07 | 厦门大学 | Method for detecting target nucleic acid sequence with high specificity |
| CN112592964B (en) * | 2020-12-17 | 2024-09-27 | 厦门大学 | Method for performing multiplex detection of nucleic acids |
| WO2022192758A1 (en) * | 2021-03-11 | 2022-09-15 | BioSpyder Technologies, Inc. | Tempo-span |
| WO2023043280A1 (en) * | 2021-09-17 | 2023-03-23 | 주식회사 씨젠 | Detection of target nucleic acid sequence by using synthetic non-natural base-bearing tag oligonucleotide |
| KR20240056605A (en) | 2021-09-30 | 2024-04-30 | 주식회사 씨젠 | Sample processing and analysis methods for molecular diagnostic systems |
| KR20240093623A (en) | 2021-10-21 | 2024-06-24 | 주식회사 씨젠 | Positive and negative reading device and method for target analyte in sample |
| CN114032337B (en) * | 2021-12-14 | 2024-08-02 | 广州市金圻睿生物科技有限责任公司 | Respiratory tract pathogen detection kit and preparation method and application thereof |
| CN114134219A (en) * | 2021-12-14 | 2022-03-04 | 广州市金圻睿生物科技有限责任公司 | Multiple nucleic acid detection system and preparation method and application thereof |
| KR20240028084A (en) | 2022-08-24 | 2024-03-05 | 주식회사 멀티렉스 | Label-conjugated Tag Probe and Uses thereof |
| WO2024106890A1 (en) * | 2022-11-16 | 2024-05-23 | 주식회사 씨젠 | Detection of target nucleic acid by quenching-pto cleavage and extension (q-ptoce) assay |
| WO2024181774A1 (en) * | 2023-02-28 | 2024-09-06 | Seegene, Inc. | Detection of target nucleic acid by lpho-assisted pto cleavage and extension assay |
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| MX2017015093A (en) | 2011-01-11 | 2023-03-10 | Seegene Inc | Detection of target nucleic acid sequences by pto cleavage and extension assay. |
| KR101569479B1 (en) | 2011-03-29 | 2015-11-16 | 주식회사 씨젠 | Detection of Target Nucleic Acid Sequence by PTO Cleavage and Extension-Dependent Cleavage |
| KR20130101952A (en) | 2012-02-02 | 2013-09-16 | 주식회사 씨젠 | Detection of target nucleic acid sequence by pto cleavage and extension-dependent hybridization |
-
2012
- 2012-03-20 KR KR1020120028429A patent/KR20130101952A/en unknown
- 2012-07-03 AU AU2012368436A patent/AU2012368436B2/en active Active
- 2012-07-03 RU RU2014133695A patent/RU2608501C2/en active
- 2012-07-03 CN CN201610320413.7A patent/CN106011234B/en active Active
- 2012-07-03 CN CN201280071069.2A patent/CN104145029B/en active Active
- 2012-07-03 JP JP2014555469A patent/JP6005180B2/en active Active
- 2012-07-03 KR KR1020147022148A patent/KR101832867B1/en active IP Right Grant
- 2012-07-03 US US14/374,567 patent/US9868980B2/en active Active
- 2012-07-03 MX MX2014009403A patent/MX361903B/en active IP Right Grant
- 2012-07-03 EP EP12867064.3A patent/EP2809797B1/en active Active
- 2012-07-03 CA CA2862488A patent/CA2862488C/en active Active
- 2012-07-03 SG SG11201404349YA patent/SG11201404349YA/en unknown
- 2012-07-03 WO PCT/KR2012/005281 patent/WO2013115442A1/en active Application Filing
- 2012-07-03 BR BR112014018940-4A patent/BR112014018940B1/en active IP Right Grant
-
2014
- 2014-07-23 IL IL233773A patent/IL233773B/en active IP Right Grant
- 2014-07-24 ZA ZA2014/05463A patent/ZA201405463B/en unknown
- 2014-07-30 NO NO20140948A patent/NO20140948A1/en not_active Application Discontinuation
-
2016
- 2016-07-13 AU AU2016204887A patent/AU2016204887B2/en active Active
-
2017
- 2017-12-27 US US15/854,891 patent/US10731203B2/en active Active
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