SG11201403874SA - Oral administrable pharmaceutical composition - Google Patents

Oral administrable pharmaceutical composition

Info

Publication number
SG11201403874SA
SG11201403874SA SG11201403874SA SG11201403874SA SG11201403874SA SG 11201403874S A SG11201403874S A SG 11201403874SA SG 11201403874S A SG11201403874S A SG 11201403874SA SG 11201403874S A SG11201403874S A SG 11201403874SA SG 11201403874S A SG11201403874S A SG 11201403874SA
Authority
SG
Singapore
Prior art keywords
pharmaceutical composition
administrable pharmaceutical
oral administrable
oral
composition
Prior art date
Application number
SG11201403874SA
Inventor
Yoshito Ohnishi
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48984243&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201403874S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of SG11201403874SA publication Critical patent/SG11201403874SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11201403874SA 2012-02-15 2013-02-14 Oral administrable pharmaceutical composition SG11201403874SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012031143 2012-02-15
PCT/JP2013/053513 WO2013122134A1 (en) 2012-02-15 2013-02-14 Oral pharmaceutical composition

Publications (1)

Publication Number Publication Date
SG11201403874SA true SG11201403874SA (en) 2014-10-30

Family

ID=48984243

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201403874SA SG11201403874SA (en) 2012-02-15 2013-02-14 Oral administrable pharmaceutical composition

Country Status (25)

Country Link
US (2) US20140356431A1 (en)
EP (1) EP2815753B1 (en)
JP (1) JP5798641B2 (en)
KR (2) KR20150001717A (en)
CN (1) CN104105491B (en)
AU (1) AU2013219382B2 (en)
BR (1) BR112014018273B1 (en)
CA (1) CA2861480C (en)
CY (1) CY1120530T1 (en)
DK (1) DK2815753T3 (en)
ES (1) ES2683825T3 (en)
HK (1) HK1199822A1 (en)
HR (1) HRP20181193T1 (en)
HU (1) HUE039487T2 (en)
LT (1) LT2815753T (en)
MX (1) MX355885B (en)
MY (1) MY155922A (en)
PL (1) PL2815753T3 (en)
PT (1) PT2815753T (en)
RS (1) RS57505B1 (en)
RU (1) RU2600831C2 (en)
SG (1) SG11201403874SA (en)
SI (1) SI2815753T1 (en)
TW (1) TWI503122B (en)
WO (1) WO2013122134A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106551946B (en) * 2015-09-24 2020-02-14 江苏奥赛康药业有限公司 Pharmaceutical composition containing trifluorothymidine and tipyrimidine hydrochloride and preparation method thereof
CN106913580A (en) * 2015-12-27 2017-07-04 南京圣和药业股份有限公司 A kind of pharmaceutical composition of the TEPA of hydrochloric acid containing Trifluridine drag-line and its application
CN106018573B (en) * 2016-03-16 2018-09-18 江苏悦兴药业有限公司 Hydrochloric acid replaces the method for detecting purity than drawing west in a kind of TAS-102
CN105963271A (en) * 2016-06-01 2016-09-28 国药心制药有限公司 Pharmaceutical adjuvant composition and floxuridine and hydrochloric acid substituted pyrimidine film-coated tablets
EP3730935A4 (en) 2017-12-22 2022-02-23 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine- and/or tipiracil-derived analogs
US10866219B2 (en) * 2017-12-22 2020-12-15 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine- and/or tipiracil-related substance
US10816517B2 (en) * 2018-01-05 2020-10-27 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine-related substance by high-performance liquid chromatography
WO2019135405A1 (en) 2018-01-05 2019-07-11 大鵬薬品工業株式会社 Detection method for analog derived from trifluridine
US11730753B2 (en) 2018-03-03 2023-08-22 Natco Pharma Limited Stable pharmaceutical compositions comprising trifluridine and tipiracil hydrochloride

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69629156T2 (en) * 1995-03-29 2004-05-06 Taiho Pharmaceutical Co. Ltd. URACIL DERIVATIVES AND ANTITUM-EFFECT AMPLIFIERS CONTAINING THEM AND ANTITUARY AGENTS
JPH11322604A (en) * 1998-05-06 1999-11-24 Pola Chem Ind Inc Pharmaceutical preparation containing diphenylpiperazine compound
AU782005B2 (en) 1999-05-21 2005-06-30 Kissei Pharmaceutical Co. Ltd. Immediate release medicinal compositions for oral use
JP4110347B2 (en) * 1999-11-05 2008-07-02 大鵬薬品工業株式会社 Anti-HIV agent
JP4601934B2 (en) * 2003-10-06 2010-12-22 ナガセ医薬品株式会社 Ubidecarenone tablets
JP2005314413A (en) * 2004-04-02 2005-11-10 Ono Pharmaceut Co Ltd Medicine composition for oral administration
PE20060484A1 (en) * 2004-07-14 2006-07-06 Ucb Farchim Sa LIQUID PHARMACEUTICAL PREPARATIONS CONTAINING A BENZHYDRIL PIPERIZINE COMPOUND
SI1849470T2 (en) * 2005-01-26 2024-05-31 Taiho Pharmaceutical Co., Ltd. Anticancer drug containing alpha, alpha, alpha-trifluorothymidine and thymidine phosphorylase inhibitor
US7799783B2 (en) * 2005-01-26 2010-09-21 Taiho Pharmaceutical Co., Ltd. Method of administrating an anticancer drug containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor
CA2649256C (en) * 2006-04-13 2013-09-10 Taiho Pharmaceutical Co., Ltd. Therapeutic agent for inflammatory bowel disease
JP2007284390A (en) * 2006-04-18 2007-11-01 Ohara Yakuhin Kogyo Kk Imidapril hydrochloride-containing tablet
RU2346684C2 (en) * 2007-04-04 2009-02-20 Закрытое акционерное общество "Биологические исследования и системы" Sygetin based pharmaceutical composition

Also Published As

Publication number Publication date
US20140356431A1 (en) 2014-12-04
BR112014018273A8 (en) 2021-09-28
AU2013219382B2 (en) 2016-05-05
BR112014018273B1 (en) 2023-04-25
HRP20181193T1 (en) 2018-10-19
AU2013219382A1 (en) 2014-08-14
BR112014018273A2 (en) 2017-06-20
KR20170029021A (en) 2017-03-14
ES2683825T3 (en) 2018-09-28
SI2815753T1 (en) 2018-11-30
JP5798641B2 (en) 2015-10-21
RU2600831C2 (en) 2016-10-27
EP2815753A1 (en) 2014-12-24
JPWO2013122134A1 (en) 2015-05-18
CA2861480C (en) 2019-02-12
TWI503122B (en) 2015-10-11
TW201336498A (en) 2013-09-16
LT2815753T (en) 2018-09-10
CA2861480A1 (en) 2013-08-22
CN104105491A (en) 2014-10-15
CY1120530T1 (en) 2019-07-10
RS57505B1 (en) 2018-10-31
WO2013122134A1 (en) 2013-08-22
RU2014137096A (en) 2016-04-10
KR20150001717A (en) 2015-01-06
DK2815753T3 (en) 2018-08-13
EP2815753B1 (en) 2018-05-16
HUE039487T2 (en) 2019-01-28
US20210220384A1 (en) 2021-07-22
MX355885B (en) 2018-05-02
KR101951575B1 (en) 2019-02-22
PL2815753T3 (en) 2018-10-31
PT2815753T (en) 2018-10-08
HK1199822A1 (en) 2015-07-24
EP2815753A4 (en) 2015-07-01
MY155922A (en) 2015-12-16
MX2014009833A (en) 2014-09-11
CN104105491B (en) 2016-06-15

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