SG11201403308QA - Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin - Google Patents

Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin

Info

Publication number
SG11201403308QA
SG11201403308QA SG11201403308QA SG11201403308QA SG11201403308QA SG 11201403308Q A SG11201403308Q A SG 11201403308QA SG 11201403308Q A SG11201403308Q A SG 11201403308QA SG 11201403308Q A SG11201403308Q A SG 11201403308QA SG 11201403308Q A SG11201403308Q A SG 11201403308QA
Authority
SG
Singapore
Prior art keywords
brexpiprazole
cyclodextrin
pharmaceutical preparation
substituted beta
beta
Prior art date
Application number
SG11201403308QA
Inventor
Tetsuya Hasegawa
Hidekazu Toyobuku
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47603961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201403308Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SG11201403308QA publication Critical patent/SG11201403308QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
SG11201403308QA 2011-12-28 2012-12-28 Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin SG11201403308QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161580708P 2011-12-28 2011-12-28
PCT/JP2012/084313 WO2013100204A1 (en) 2011-12-28 2012-12-28 Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin

Publications (1)

Publication Number Publication Date
SG11201403308QA true SG11201403308QA (en) 2014-07-30

Family

ID=47603961

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201403308QA SG11201403308QA (en) 2011-12-28 2012-12-28 Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin
SG10201605188UA SG10201605188UA (en) 2011-12-28 2012-12-28 Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201605188UA SG10201605188UA (en) 2011-12-28 2012-12-28 Pharmaceutical preparation comprising brexpiprazole and substituted beta - cyclodextrin

Country Status (20)

Country Link
US (4) US20150005314A1 (en)
EP (1) EP2797631A1 (en)
JP (1) JP6246715B2 (en)
KR (1) KR20140107378A (en)
CN (2) CN104023750A (en)
AR (1) AR089486A1 (en)
AU (1) AU2012360716B2 (en)
BR (1) BR112014015885A8 (en)
CA (1) CA2860282A1 (en)
CL (1) CL2014001754A1 (en)
CO (1) CO7010828A2 (en)
EA (1) EA201491288A1 (en)
HK (1) HK1198939A1 (en)
IL (1) IL233127A0 (en)
MX (1) MX2014007979A (en)
PH (1) PH12014501425A1 (en)
SG (2) SG11201403308QA (en)
TW (1) TW201332572A (en)
WO (1) WO2013100204A1 (en)
ZA (1) ZA201405039B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20200109A1 (en) 2012-04-23 2017-06-16 Otsuka Pharma Co Ltd Injectable preparation
US9675051B2 (en) * 2014-07-21 2017-06-13 Nicholas Jay Bonge, JR. Wireless animal training, monitoring and remote control system
JP6513461B2 (en) * 2015-04-14 2019-05-15 帝國製薬株式会社 Transdermal preparation of brexpiprazole
CN105078910B (en) * 2015-09-22 2018-05-22 成都欣捷高新技术开发有限公司 It is a kind of containing according to lyophilized oral formulations of piperazine azoles and preparation method thereof
EP3545950A1 (en) 2018-03-26 2019-10-02 Adamed sp. z o.o. Pharmaceutical composition comprising brexpiprazole
CN115192549A (en) * 2021-04-13 2022-10-18 上海博志研新药物技术有限公司 Brexpiprazole oral thin film agent, preparation method and application thereof
WO2022218357A1 (en) * 2021-04-13 2022-10-20 上海博志研新药物技术有限公司 Brexpiprazole orally soluble film clathrate, and preparation method therefor and use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US580708A (en) 1897-04-13 Robert orme
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (en) 1990-01-23 1999-01-15 . Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
UA57734C2 (en) 1996-05-07 2003-07-15 Пфайзер Інк. Arylheterocyclic inclusion complexes
JPH10194996A (en) 1996-12-25 1998-07-28 Janssen Pharmaceut Nv Acylated cyclodextrin-containing pharmaceutical composition
US7115587B2 (en) * 2002-08-20 2006-10-03 Bristol-Myers Squibb Company Aripiprazole complex formulation and method
TWI320783B (en) * 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
JP4315393B2 (en) * 2005-04-14 2009-08-19 大塚製薬株式会社 Heterocyclic compounds
AR085840A1 (en) * 2011-04-05 2013-10-30 Otsuka Pharma Co Ltd MEDICINAL PRODUCT CONTAINING A COMPOUND THAT IS 7- [4- (4-BENZO [B] TIOFEN-4-IL-PIPERAZIN-1-IL) BUTOXI] -1H-QUINOLIN-2-ONA
JO3227B1 (en) * 2011-09-08 2018-03-08 Otsuka Pharma Co Ltd Piperazine-substituted benzothiophene deriveatives as antipsychotic agents

Also Published As

Publication number Publication date
AU2012360716B2 (en) 2017-08-17
BR112014015885A2 (en) 2017-06-13
AR089486A1 (en) 2014-08-27
CO7010828A2 (en) 2014-07-31
CA2860282A1 (en) 2013-07-04
IL233127A0 (en) 2014-07-31
HK1198939A1 (en) 2015-06-19
NZ626379A (en) 2015-09-25
KR20140107378A (en) 2014-09-04
EA201491288A1 (en) 2014-11-28
US20160310617A1 (en) 2016-10-27
CL2014001754A1 (en) 2014-10-03
BR112014015885A8 (en) 2017-07-04
JP6246715B2 (en) 2017-12-13
WO2013100204A1 (en) 2013-07-04
PH12014501425A1 (en) 2014-09-22
US20170151237A1 (en) 2017-06-01
MX2014007979A (en) 2014-08-21
EP2797631A1 (en) 2014-11-05
JP2015503501A (en) 2015-02-02
US20150005314A1 (en) 2015-01-01
CN107261153A (en) 2017-10-20
ZA201405039B (en) 2015-12-23
CN104023750A (en) 2014-09-03
AU2012360716A1 (en) 2014-07-31
TW201332572A (en) 2013-08-16
US20180008599A1 (en) 2018-01-11
SG10201605188UA (en) 2016-07-28

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