SG11201402030VA - Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediates - Google Patents
Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediatesInfo
- Publication number
- SG11201402030VA SG11201402030VA SG11201402030VA SG11201402030VA SG11201402030VA SG 11201402030V A SG11201402030V A SG 11201402030VA SG 11201402030V A SG11201402030V A SG 11201402030VA SG 11201402030V A SG11201402030V A SG 11201402030VA SG 11201402030V A SG11201402030V A SG 11201402030VA
- Authority
- SG
- Singapore
- Prior art keywords
- phenylsulfonylprolinamide
- acyl
- derivatives
- preparation
- new intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11188728 | 2011-11-11 | ||
| PCT/EP2012/072078 WO2013068434A1 (en) | 2011-11-11 | 2012-11-08 | Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201402030VA true SG11201402030VA (en) | 2014-06-27 |
Family
ID=47143910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201402030VA SG11201402030VA (en) | 2011-11-11 | 2012-11-08 | Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediates |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8796471B2 (en) |
| EP (1) | EP2776392B1 (en) |
| JP (1) | JP5852254B2 (en) |
| KR (1) | KR101620769B1 (en) |
| CN (1) | CN103930400B (en) |
| AR (1) | AR088816A1 (en) |
| AU (1) | AU2012334123B2 (en) |
| BR (1) | BR112014011248B1 (en) |
| CA (1) | CA2853877C (en) |
| DK (1) | DK2776392T3 (en) |
| ES (1) | ES2582643T3 (en) |
| HK (1) | HK1194733A1 (en) |
| HU (1) | HUE029182T2 (en) |
| IL (1) | IL232424A (en) |
| MX (1) | MX339996B (en) |
| MY (1) | MY167569A (en) |
| PL (1) | PL2776392T3 (en) |
| RU (1) | RU2615997C2 (en) |
| SG (1) | SG11201402030VA (en) |
| SI (1) | SI2776392T1 (en) |
| WO (1) | WO2013068434A1 (en) |
| ZA (1) | ZA201403152B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103333094B (en) * | 2013-06-19 | 2015-05-13 | 广东肇庆星湖生物科技股份有限公司 | Process method for crystallization purification of proline |
| WO2016034602A1 (en) * | 2014-09-05 | 2016-03-10 | F. Hoffmann-La Roche Ag | Solid forms of (2s,4r)-4-[4-(1-methyl-1h-pyrazol-4-yl)-2-trifluoromethyl-benzenesulfonyl]-1-(1-trifluoromethyl-cyclopropanecarbonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide |
| MX2018009638A (en) * | 2016-02-26 | 2018-09-11 | Hoffmann La Roche | Novel pyrrolidine derivatives. |
| WO2018139438A1 (en) * | 2017-01-24 | 2018-08-02 | アステラス製薬株式会社 | Phenyldifluoromethyl-substituted prolineamide compound |
| EP3725769A1 (en) * | 2019-04-17 | 2020-10-21 | Newron Pharmaceuticals S.p.A. | Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives |
| CN111825582B (en) * | 2020-08-12 | 2022-04-08 | 江西理工大学 | Method for synthesizing beta-thiocarbonyl compound by taking arylsulfonyl chloride as sulfur source |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69911737T2 (en) * | 1998-09-09 | 2004-08-12 | Nippon Finechemical Co., Ltd. | METHOD FOR PRODUCING AROMATIC SULFUR COMPOUNDS |
| CN101475517B (en) * | 2009-01-15 | 2012-08-15 | 河南大学 | Preparation of symmetrical disulfide bond-bearing compound |
| NZ595073A (en) * | 2009-04-20 | 2012-11-30 | Hoffmann La Roche | Proline derivatives as cathepsin inhibitors |
-
2012
- 2012-11-08 DK DK12783216.0T patent/DK2776392T3/en active
- 2012-11-08 EP EP12783216.0A patent/EP2776392B1/en active Active
- 2012-11-08 KR KR1020147015454A patent/KR101620769B1/en active IP Right Grant
- 2012-11-08 SG SG11201402030VA patent/SG11201402030VA/en unknown
- 2012-11-08 HU HUE12783216A patent/HUE029182T2/en unknown
- 2012-11-08 JP JP2014540444A patent/JP5852254B2/en active Active
- 2012-11-08 CN CN201280055223.7A patent/CN103930400B/en active Active
- 2012-11-08 US US13/671,586 patent/US8796471B2/en active Active
- 2012-11-08 BR BR112014011248-7A patent/BR112014011248B1/en active IP Right Grant
- 2012-11-08 WO PCT/EP2012/072078 patent/WO2013068434A1/en active Application Filing
- 2012-11-08 MY MYPI2014701188A patent/MY167569A/en unknown
- 2012-11-08 AU AU2012334123A patent/AU2012334123B2/en not_active Ceased
- 2012-11-08 RU RU2014122116A patent/RU2615997C2/en active
- 2012-11-08 ES ES12783216.0T patent/ES2582643T3/en active Active
- 2012-11-08 MX MX2014005689A patent/MX339996B/en active IP Right Grant
- 2012-11-08 CA CA2853877A patent/CA2853877C/en active Active
- 2012-11-08 SI SI201230621A patent/SI2776392T1/en unknown
- 2012-11-08 PL PL12783216.0T patent/PL2776392T3/en unknown
- 2012-11-09 AR ARP120104226A patent/AR088816A1/en unknown
-
2014
- 2014-04-30 ZA ZA2014/03152A patent/ZA201403152B/en unknown
- 2014-05-01 IL IL232424A patent/IL232424A/en active IP Right Grant
- 2014-08-06 HK HK14108048.9A patent/HK1194733A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR088816A1 (en) | 2014-07-10 |
| US20130123512A1 (en) | 2013-05-16 |
| IL232424A0 (en) | 2014-06-30 |
| AU2012334123B2 (en) | 2016-12-15 |
| RU2615997C2 (en) | 2017-04-12 |
| BR112014011248A2 (en) | 2017-05-09 |
| DK2776392T3 (en) | 2016-07-04 |
| US8796471B2 (en) | 2014-08-05 |
| MX2014005689A (en) | 2014-08-08 |
| NZ623851A (en) | 2015-06-26 |
| MY167569A (en) | 2018-09-20 |
| ES2582643T3 (en) | 2016-09-14 |
| CA2853877C (en) | 2019-10-01 |
| JP2014532740A (en) | 2014-12-08 |
| EP2776392B1 (en) | 2016-05-18 |
| ZA201403152B (en) | 2015-07-29 |
| CN103930400A (en) | 2014-07-16 |
| IL232424A (en) | 2017-01-31 |
| MX339996B (en) | 2016-06-21 |
| EP2776392A1 (en) | 2014-09-17 |
| BR112014011248B1 (en) | 2020-11-17 |
| JP5852254B2 (en) | 2016-02-03 |
| PL2776392T3 (en) | 2016-11-30 |
| RU2014122116A (en) | 2015-12-20 |
| CA2853877A1 (en) | 2013-05-16 |
| HUE029182T2 (en) | 2017-02-28 |
| KR20140098123A (en) | 2014-08-07 |
| SI2776392T1 (en) | 2016-08-31 |
| WO2013068434A1 (en) | 2013-05-16 |
| KR101620769B1 (en) | 2016-05-12 |
| CN103930400B (en) | 2016-04-20 |
| HK1194733A1 (en) | 2014-10-24 |
| AU2012334123A1 (en) | 2014-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20170961T1 (en) | Process for preparing carbamoylpyridone derivatives and intermediates | |
| IL246265B (en) | Process for preparing intermediates for the preparation of 5-fluoro-1h-pyrazolopyridines and some such compounds | |
| HRP20160692T1 (en) | Process for the production of estetrol intermediates | |
| EP2744336A4 (en) | Process and intermediates for preparing macrolactams | |
| ZA201305972B (en) | Method for the preparation of biphephos | |
| IL237655A0 (en) | Improved process for preparation of vilanterol and intermediates | |
| ZA201308445B (en) | Process for the production of estetrol intermediates | |
| SG11201400939YA (en) | Process for the preparation of methoxymelonal | |
| SG11201406623PA (en) | Process for the preparation of rivaroxaban and intermediates thereof | |
| ZA201403736B (en) | Process for the preparation of sterol derivatives | |
| HK1194733A1 (en) | Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and intermediates 1--4- | |
| ZA201306212B (en) | An improved process for the preparation of voriconazole and intermediates thereof | |
| PT2702045T (en) | Novel process for the preparation of etravirine | |
| PL391303A1 (en) | New pyrimidepyrimidine derivative and process for the preparation of new pyrimidepyrimidine derivative | |
| PL391316A1 (en) | New pyrimidepyrimidine derivative and process for the preparation of new pyrimidepyrimidine derivative | |
| PL394420A1 (en) | process for the preparation of dilauroilfluorescein | |
| PL394378A1 (en) | Process for the preparation of E-2-amine-4-nitrostillbenes | |
| PL395175A1 (en) | New dextrometorfan derivatives and process for the preparation thereof |