SG11201401018XA - Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity - Google Patents

Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity

Info

Publication number
SG11201401018XA
SG11201401018XA SG11201401018XA SG11201401018XA SG11201401018XA SG 11201401018X A SG11201401018X A SG 11201401018XA SG 11201401018X A SG11201401018X A SG 11201401018XA SG 11201401018X A SG11201401018X A SG 11201401018XA SG 11201401018X A SG11201401018X A SG 11201401018XA
Authority
SG
Singapore
Prior art keywords
high selectivity
antimicrobial activities
spectrum antimicrobial
excellent broad
peptidopolysaccharides
Prior art date
Application number
SG11201401018XA
Inventor
Bee Eng Mary Chan
Peng Li
Original Assignee
Univ Nanyang Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nanyang Tech filed Critical Univ Nanyang Tech
Publication of SG11201401018XA publication Critical patent/SG11201401018XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
SG11201401018XA 2011-10-03 2012-10-03 Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity SG11201401018XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161542321P 2011-10-03 2011-10-03
PCT/SG2012/000371 WO2013052012A1 (en) 2011-10-03 2012-10-03 Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity

Publications (1)

Publication Number Publication Date
SG11201401018XA true SG11201401018XA (en) 2014-06-27

Family

ID=48044004

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201401018XA SG11201401018XA (en) 2011-10-03 2012-10-03 Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity
SG10201510437WA SG10201510437WA (en) 2011-10-03 2012-10-03 Cationic peptidopolysaccharides with excellent broad-spectrum antimicrobial activities and high selectivity

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201510437WA SG10201510437WA (en) 2011-10-03 2012-10-03 Cationic peptidopolysaccharides with excellent broad-spectrum antimicrobial activities and high selectivity

Country Status (6)

Country Link
US (2) US20140228279A1 (en)
EP (1) EP2748204B1 (en)
JP (2) JP6488129B2 (en)
CN (1) CN103857702B (en)
SG (2) SG11201401018XA (en)
WO (1) WO2013052012A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112042644B (en) * 2016-03-31 2022-03-11 积水化学工业株式会社 Antibacterial and antiviral composition
CN107344971A (en) * 2016-05-05 2017-11-14 中国科学院理化技术研究所 A kind of poly- ε-lysine modified chitosan and preparation method thereof
CN107496439B (en) * 2016-06-14 2021-06-29 哈尔滨盈聚生物科技有限公司 Chitosan derivative-based disinfectant and preparation method thereof
CN107496440B (en) * 2016-06-14 2021-06-29 哈尔滨盈聚生物科技有限公司 Gynecological washing and caring product and preparation method thereof
CN108096271B (en) * 2016-11-25 2021-07-23 中国科学院理化技术研究所 Child gynecological lotion and preparation method thereof
CN112805305B (en) * 2018-09-19 2023-03-21 南洋理工大学 Biohybrid peptidoglycan oligomers
JP7406789B2 (en) * 2019-10-30 2023-12-28 国立大学法人広島大学 Methods for isolating bacterial membrane vesicles, isolation kits, and methods for their removal
CN116891542B (en) * 2023-09-11 2023-12-15 青岛溯博生物技术有限公司 Cationic carboxymethyl chitosan with antibacterial effect and application thereof

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US5280113A (en) * 1989-08-16 1994-01-18 Monsanto Company Method for producing synthetic N-linked glycoconjugates
EP0544000B1 (en) * 1990-08-17 1997-05-02 Drug Delivery System Institute, Ltd. N-acetylcarboxymethylchitosan derivative and production thereof
JP4234803B2 (en) * 1997-10-27 2009-03-04 久光製薬株式会社 Pharmaceutical composition with controlled drug release rate
JP2000302803A (en) * 1999-04-22 2000-10-31 Noevir Co Ltd Partially deacetylated chitin or chitosan derivative with selectively substituted free amino group by amino acid and peptide and having substantially no substituted hydroxide group, and its manufacture
CN1321696A (en) * 2000-04-28 2001-11-14 中国科学院成都有机化学研究所 Polyether-polyamino acid double block copolymer and its preparation method and application
US6338859B1 (en) * 2000-06-29 2002-01-15 Labopharm Inc. Polymeric micelle compositions
JP2003105001A (en) * 2001-09-28 2003-04-09 Nagoya Industrial Science Research Inst Method for manufacturing graft copolymer of partially deacetylated chitin or chitosan and graft copolymer
JP2003277401A (en) * 2002-03-27 2003-10-02 Guroobu Kk Polysaccharide amino acid carbamate derivative
CN100475837C (en) * 2004-06-11 2009-04-08 北京键凯科技有限公司 Branched polyglycol-amino acid oligopeptide and active derivative and medicinal composition thereof
CN1597698A (en) * 2004-07-21 2005-03-23 南开大学 Cation antibacterial peptide
CN101426507A (en) * 2005-05-27 2009-05-06 佐治亚州立大学研究基金会 Use of polyamines with antibiotics
CA2608824A1 (en) * 2006-10-31 2008-04-30 University Of New Brunswick Antimicrobial and bacteriostatic-modified polymers for cellulose fibres
KR100825519B1 (en) * 2007-01-05 2008-04-25 주식회사 바이오폴리메드 A chitosan based polymer conjugate and a method for producing the same
CA2687689A1 (en) * 2007-05-28 2009-03-26 University Of Manitoba Triazole-based aminoglycoside-peptide conjugates and methods of use
US20080300389A1 (en) * 2007-06-04 2008-12-04 Yang David J Metal-polysaccharide conjugates: compositions, synthesis and methods for cancer therapy
EP2326671A4 (en) * 2008-09-05 2012-10-03 Ca Nat Research Council Lps based vaccines
CN101429233B (en) * 2008-10-06 2011-10-19 南开大学 Polyglycol modified antimicrobial peptide and uses thereof
CN102153742B (en) * 2011-01-21 2012-11-21 中国科学院长春应用化学研究所 Poly-amino acid grafted copolymer and method for preparing same

Also Published As

Publication number Publication date
SG10201510437WA (en) 2016-01-28
JP6488129B2 (en) 2019-03-20
EP2748204A4 (en) 2015-01-21
JP2019014905A (en) 2019-01-31
CN103857702A (en) 2014-06-11
EP2748204A1 (en) 2014-07-02
JP2014528995A (en) 2014-10-30
US20140228279A1 (en) 2014-08-14
CN103857702B (en) 2018-01-26
US20180201652A1 (en) 2018-07-19
EP2748204B1 (en) 2016-04-20
WO2013052012A1 (en) 2013-04-11

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