SG11201400769PA - Quinolyl-containing Hydroxamic Acid Compound and Preparation Method Thereof, and Pharmaceutical Composition Containing This Compound and Use Thereof - Google Patents
Quinolyl-containing Hydroxamic Acid Compound and Preparation Method Thereof, and Pharmaceutical Composition Containing This Compound and Use ThereofInfo
- Publication number
- SG11201400769PA SG11201400769PA SG11201400769PA SG11201400769PA SG11201400769PA SG 11201400769P A SG11201400769P A SG 11201400769PA SG 11201400769P A SG11201400769P A SG 11201400769PA SG 11201400769P A SG11201400769P A SG 11201400769PA SG 11201400769P A SG11201400769P A SG 11201400769PA
- Authority
- SG
- Singapore
- Prior art keywords
- compound
- quinolyl
- preparation
- pharmaceutical composition
- hydroxamic acid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110278403.9A CN102408411B (en) | 2011-09-19 | 2011-09-19 | Hydroximic acid compound containing quinolyl and preparation method thereof, and drug composition containing the compound and use thereof |
PCT/CN2011/080213 WO2013040801A1 (en) | 2011-09-19 | 2011-09-27 | Hydroxamic acid compound containing quinolyl and preparation method thereof, and pharmaceutical composition containing this compound and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201400769PA true SG11201400769PA (en) | 2014-07-30 |
Family
ID=45910798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201400769PA SG11201400769PA (en) | 2011-09-19 | 2011-09-27 | Quinolyl-containing Hydroxamic Acid Compound and Preparation Method Thereof, and Pharmaceutical Composition Containing This Compound and Use Thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US9186318B2 (en) |
EP (1) | EP2769976B8 (en) |
JP (1) | JP5795826B2 (en) |
KR (1) | KR101879908B1 (en) |
CN (1) | CN102408411B (en) |
AU (1) | AU2011377440B2 (en) |
CA (1) | CA2858033C (en) |
HK (1) | HK1171009A1 (en) |
NZ (1) | NZ623923A (en) |
RU (1) | RU2573633C2 (en) |
SG (1) | SG11201400769PA (en) |
TW (1) | TWI472513B (en) |
WO (1) | WO2013040801A1 (en) |
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CA2871092C (en) | 2012-04-23 | 2017-05-09 | Nemaska Lithium Inc. | Processes for preparing lithium hydroxide |
WO2013177367A2 (en) | 2012-05-23 | 2013-11-28 | The Johns Hopkins University | Compounds and methods of use thereof for treating neurodegenerative disorders |
RS57299B1 (en) | 2012-05-30 | 2018-08-31 | Nemaska Lithium Inc | Processes for preparing lithium carbonate |
PT2971252T (en) | 2013-03-15 | 2021-04-06 | Nemaska Lithium Inc | Processes for preparing lithium hydroxide |
PE20160658A1 (en) | 2013-10-11 | 2016-08-05 | Alios Biopharma Inc | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF |
KR102614113B1 (en) | 2013-10-23 | 2023-12-13 | 네마스카 리튬 인코포레이션 | Processes for preparing lithium carbonate |
WO2015119122A1 (en) * | 2014-02-04 | 2015-08-13 | アステラス製薬株式会社 | Medicinal composition comprising diamino heterocyclic carboxamide compound as active ingredient |
ES2863453T3 (en) | 2014-02-24 | 2021-10-11 | Nemaska Lithium Inc | Procedures for handling lithium-containing materials |
WO2016183071A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Hetero-tricyclic compounds and their use for the treatment of cancer |
KR20180041135A (en) | 2015-07-16 | 2018-04-23 | 어레이 바이오파마 인크. | A pyrazolo [1,5-a] pyridine compound substituted as a RET kinase inhibitor |
WO2017027717A1 (en) | 2015-08-12 | 2017-02-16 | Incyte Corporation | Bicyclic fused pyrimidine compounds as tam inhibitors |
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CA2940509A1 (en) | 2016-08-26 | 2018-02-26 | Nemaska Lithium Inc. | Processes for treating aqueous compositions comprising lithium sulfate and sulfuric acid |
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CN108329298A (en) * | 2017-01-17 | 2018-07-27 | 南昌弘益药业有限公司 | A kind of quinolines noval chemical compound preparation method |
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WO2018136663A1 (en) | 2017-01-18 | 2018-07-26 | Array Biopharma, Inc. | Ret inhibitors |
JOP20190213A1 (en) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | Macrocyclic compounds as ros1 kinase inhibitors |
CN108623565A (en) * | 2017-03-23 | 2018-10-09 | 南昌弘益药业有限公司 | A kind of preparation method of compound |
JP6934261B2 (en) * | 2017-05-24 | 2021-09-15 | アビスコ セラピューティクス カンパニー リミテッド | N- (azaaryl) cyclolactam-1-carboxamide derivative, its production method and application |
JP2020535168A (en) | 2017-09-27 | 2020-12-03 | インサイト・コーポレイションIncyte Corporation | Salts of pyrorotriazine derivatives useful as TAM inhibitors |
TWI791053B (en) | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | Crystalline forms of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile and pharmaceutical composition thereof |
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-
2011
- 2011-09-19 CN CN201110278403.9A patent/CN102408411B/en active Active
- 2011-09-27 WO PCT/CN2011/080213 patent/WO2013040801A1/en active Application Filing
- 2011-09-27 RU RU2014112345/04A patent/RU2573633C2/en active
- 2011-09-27 EP EP11872645.4A patent/EP2769976B8/en not_active Not-in-force
- 2011-09-27 NZ NZ623923A patent/NZ623923A/en not_active IP Right Cessation
- 2011-09-27 KR KR1020147010391A patent/KR101879908B1/en active IP Right Grant
- 2011-09-27 SG SG11201400769PA patent/SG11201400769PA/en unknown
- 2011-09-27 AU AU2011377440A patent/AU2011377440B2/en not_active Ceased
- 2011-09-27 CA CA2858033A patent/CA2858033C/en not_active Expired - Fee Related
- 2011-09-27 JP JP2014531066A patent/JP5795826B2/en not_active Expired - Fee Related
- 2011-09-27 US US14/345,922 patent/US9186318B2/en not_active Expired - Fee Related
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2012
- 2012-08-06 HK HK12107695.9A patent/HK1171009A1/en not_active IP Right Cessation
- 2012-08-09 TW TW101128702A patent/TWI472513B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
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KR101879908B1 (en) | 2018-07-18 |
TW201313683A (en) | 2013-04-01 |
EP2769976A1 (en) | 2014-08-27 |
US20140221425A1 (en) | 2014-08-07 |
JP2014526522A (en) | 2014-10-06 |
RU2573633C2 (en) | 2016-01-27 |
EP2769976B1 (en) | 2017-08-02 |
RU2014112345A (en) | 2015-10-27 |
US9186318B2 (en) | 2015-11-17 |
TWI472513B (en) | 2015-02-11 |
CN102408411A (en) | 2012-04-11 |
KR20140069188A (en) | 2014-06-09 |
CA2858033A1 (en) | 2013-03-28 |
AU2011377440B2 (en) | 2017-01-05 |
NZ623923A (en) | 2015-05-29 |
WO2013040801A1 (en) | 2013-03-28 |
JP5795826B2 (en) | 2015-10-14 |
EP2769976A4 (en) | 2015-06-03 |
EP2769976B8 (en) | 2017-12-13 |
HK1171009A1 (en) | 2013-03-15 |
CA2858033C (en) | 2016-01-12 |
AU2011377440A1 (en) | 2014-05-15 |
CN102408411B (en) | 2014-10-22 |
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