SG11201400665RA - Probe with multiple target region specificity and of tripartite character - Google Patents

Probe with multiple target region specificity and of tripartite character

Info

Publication number
SG11201400665RA
SG11201400665RA SG11201400665RA SG11201400665RA SG11201400665RA SG 11201400665R A SG11201400665R A SG 11201400665RA SG 11201400665R A SG11201400665R A SG 11201400665RA SG 11201400665R A SG11201400665R A SG 11201400665RA SG 11201400665R A SG11201400665R A SG 11201400665RA
Authority
SG
Singapore
Prior art keywords
tripartite
probe
character
target region
multiple target
Prior art date
Application number
SG11201400665RA
Inventor
Ben Cobb
Original Assignee
Epistem Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epistem Ltd filed Critical Epistem Ltd
Publication of SG11201400665RA publication Critical patent/SG11201400665RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11201400665RA 2011-09-19 2012-09-19 Probe with multiple target region specificity and of tripartite character SG11201400665RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1116131.2A GB201116131D0 (en) 2011-09-19 2011-09-19 Probe
PCT/GB2012/052305 WO2013041853A1 (en) 2011-09-19 2012-09-19 Probe with multiple target region specificity and of tripartite character

Publications (1)

Publication Number Publication Date
SG11201400665RA true SG11201400665RA (en) 2014-04-28

Family

ID=44937474

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602026SA SG10201602026SA (en) 2011-09-19 2012-09-19 Probe with multiple target region specificity and of tripartite character
SG11201400665RA SG11201400665RA (en) 2011-09-19 2012-09-19 Probe with multiple target region specificity and of tripartite character

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201602026SA SG10201602026SA (en) 2011-09-19 2012-09-19 Probe with multiple target region specificity and of tripartite character

Country Status (15)

Country Link
US (1) US20140227683A1 (en)
EP (1) EP2758542B1 (en)
JP (1) JP6097752B2 (en)
KR (1) KR20140063780A (en)
CN (1) CN103998624B (en)
AU (1) AU2012311295A1 (en)
BR (1) BR112014006327A2 (en)
CA (1) CA2849050A1 (en)
ES (1) ES2642275T3 (en)
GB (1) GB201116131D0 (en)
IL (1) IL231443A0 (en)
MX (1) MX2014003108A (en)
RU (1) RU2014115802A (en)
SG (2) SG10201602026SA (en)
WO (1) WO2013041853A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102559661B (en) * 2012-01-18 2014-06-04 厦门基科生物科技有限公司 Novel amplification method and application of ligase reaction mediate
GB201317355D0 (en) * 2013-10-01 2013-11-13 Epistem Ltd Mutation Analysis
WO2015071552A1 (en) * 2013-11-18 2015-05-21 Teknologian Tutkimuskeskus Vtt Multi-unit probes with high specificity and a method of designing the same
US9637791B2 (en) * 2013-12-20 2017-05-02 Roche Molecular Systems, Inc. Multiplexed nucleic acid target identification by strucutre based probe cleavage
US9856521B2 (en) * 2015-01-27 2018-01-02 BioSpyder Technologies, Inc. Ligation assays in liquid phase
US11091810B2 (en) * 2015-01-27 2021-08-17 BioSpyder Technologies, Inc. Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology
US10683534B2 (en) * 2015-01-27 2020-06-16 BioSpyder Technologies, Inc. Ligation assays in liquid phase
WO2016098595A1 (en) * 2014-12-19 2016-06-23 栄研化学株式会社 Oligonucleotide probe for detecting single nucleotide polymorphism, and method for detecting single nucleotide polymorphism
JP6685138B2 (en) * 2016-01-27 2020-04-22 シスメックス株式会社 Quality control method for nucleic acid amplification, quality control reagent and reagent kit therefor
WO2019176939A1 (en) * 2018-03-15 2019-09-19 栄研化学株式会社 Oligonucleotide probe for detecting single nucleotide polymorphisms, and method for determining cis-trans configuration

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
FR2680520B1 (en) * 1991-08-22 1995-09-22 France Etat Armement METHOD FOR THE DETECTION OF NEW HYPERVARIABLE REGIONS IN A DNA SEQUENCE, NUCLEOTIDE SEQUENCES CONSTITUTING HYBRIDIZATION PROBES AND THEIR BIOLOGICAL APPLICATION.
SE9400522D0 (en) * 1994-02-16 1994-02-16 Ulf Landegren Method and reagent for detecting specific nucleotide sequences
GB9713597D0 (en) * 1997-06-28 1997-09-03 Sec Dep Of The Home Department Improvements in and relating to forensic identification
US20030165888A1 (en) 2001-07-18 2003-09-04 Brown Bob D. Oligonucleotide probes and primers comprising universal bases for diagnostic purposes
US20040086879A1 (en) * 2001-12-20 2004-05-06 Yingufu Li Tripartite molecular beacons
AU2002329063A1 (en) * 2002-09-30 2004-04-23 F.Hoffmann-La Roche Ag Oligonucleotides for genotyping thymidylate synthase gene
JP2004129544A (en) * 2002-10-09 2004-04-30 Asahi Kasei Corp Probe and method for detecting base polymorphism
EP1618215A4 (en) * 2003-05-01 2007-12-05 Gen Probe Inc Oligonucleotides comprising a molecular switch
US20050191636A1 (en) * 2004-03-01 2005-09-01 Biocept, Inc. Detection of STRP, such as fragile X syndrome
DE102004026120A1 (en) * 2004-05-28 2005-12-22 Sirs-Lab Gmbh Addressable molecular probe arrangement
WO2006095941A1 (en) * 2005-03-05 2006-09-14 Seegene, Inc. Processes using dual specificity oligonucleotide and dual specificity oligonucleotide
US20070065847A1 (en) 2005-08-11 2007-03-22 Affymetrix, Inc. Degeneratively Labeled Probes
KR20070052890A (en) 2005-11-18 2007-05-23 주식회사 씨젠 Oligonucleotides for detecting respiratory virus nucleic acids
US20070259347A1 (en) 2006-05-03 2007-11-08 Agilent Technologies, Inc. Methods of increasing the effective probe densities of arrays
EP2129789B1 (en) * 2007-01-31 2013-03-06 Celera Corporation Method of determining risk associated with breast cancer metastasis by the determination of a molecular prognostic signature.
GB0703996D0 (en) * 2007-03-01 2007-04-11 Oxitec Ltd Nucleic acid detection
BRPI0811294B8 (en) * 2007-05-09 2022-06-28 Dow Agrosciences Llc POLYNUCLEOTIDE ISOLATED, AND METHOD FOR WEED CONTROL IN AN AREA
EP2014774A1 (en) * 2007-07-11 2009-01-14 Pathofinder B.V. Assay for the simulataneous detection of multiple nucleic acid sequences in a sample
AU2008315791B2 (en) * 2007-10-22 2014-04-10 Lgc Limited Oligonucleotides and uses thereof
WO2009156479A1 (en) * 2008-06-27 2009-12-30 Meta-Iq Aps Inhibitors of carnitin-palmitoyl-transferase-1 for the treatment and prevention of disorders caused by delipidation of neural tissue
US20100099084A1 (en) * 2008-10-17 2010-04-22 Maher Albitar Detection of npm1 nucleic acid in acellular body fluids
US8409802B2 (en) * 2009-08-14 2013-04-02 Roche Molecular Systems, Inc. Format of probes to detect nucleic acid differences
WO2011027966A2 (en) * 2009-09-03 2011-03-10 Seegene, Inc. Td probe and its uses
CA2786696C (en) * 2010-01-12 2021-05-25 Jill Detmer Oligonucleotides and methods for detecting pik3ca mutations

Also Published As

Publication number Publication date
MX2014003108A (en) 2014-05-30
SG10201602026SA (en) 2016-04-28
ES2642275T3 (en) 2017-11-16
JP6097752B2 (en) 2017-03-15
CA2849050A1 (en) 2013-03-28
KR20140063780A (en) 2014-05-27
CN103998624B (en) 2017-03-22
US20140227683A1 (en) 2014-08-14
JP2014526257A (en) 2014-10-06
BR112014006327A2 (en) 2017-04-11
GB201116131D0 (en) 2011-11-02
WO2013041853A1 (en) 2013-03-28
AU2012311295A1 (en) 2014-04-03
EP2758542B1 (en) 2017-08-23
IL231443A0 (en) 2014-04-30
RU2014115802A (en) 2015-10-27
EP2758542A1 (en) 2014-07-30
CN103998624A (en) 2014-08-20

Similar Documents

Publication Publication Date Title
IL231443A0 (en) Probe with multiple target region specificity and of tripartite character
HK1255608A1 (en) Anti-htra1 antibodies and methods of use
HK1215284A1 (en) Site-specific enzymes and methods of use
ZA201400141B (en) Keto-isovalerate decarboxylase enzymes and methods of use thereof
ZA201306998B (en) Competitive and effective bradyrhizobium japonicum strains
HK1201870A1 (en) Enzymatic omega-oxidation and omega-amination of fatty acids
SG11201403276TA (en) Modified microorganisms and methods of making butadiene using same
EP2670866A4 (en) Biomarkers and methods of use thereof
EP2675471A4 (en) Hsa-related compositions and methods of use
HK1201843A1 (en) Anti-polyubiquitin antibodies and methods of use
EP2691120A4 (en) Theranostic imaging agents and methods of use
HK1199252A1 (en) Inhibitors of nedd8-activating enzyme nedd8-
HK1198122A1 (en) Eosinophil peroxidase compositions and methods of their use
EP2747211A4 (en) Contact and probe using same
ZA201307363B (en) Axmi115 variant insecticidal gene and methods for its use
EP2670245A4 (en) Alpha-ketoheterocycles and methods of making and using
EP2764121A4 (en) E1 enzyme mutants and uses thereof
IL231490A0 (en) Compositions and methods for the production and use of human cholinesterases
EP2776462A4 (en) Indolealkylamino-withasteroid conjugates and method of use
EP2580329A4 (en) Modified renilla luciferase nucleic acids and methods of use
EP2725357A4 (en) Probe for ifret and usage of same
HK1201420A1 (en) Use of amylase enzyme
GB201302086D0 (en) Fermentation methods and their products
GB201117424D0 (en) Characterization of CHO-MIF gene and protein and use thereof
TH133996B (en) Pig food and methods for feeding them