SG10202103015VA - Antibody specific to alpha-toxin of staphylococcal aureus anduses thereof - Google Patents
Antibody specific to alpha-toxin of staphylococcal aureus anduses thereofInfo
- Publication number
- SG10202103015VA SG10202103015VA SG10202103015VA SG10202103015VA SG 10202103015V A SG10202103015V A SG 10202103015VA SG 10202103015V A SG10202103015V A SG 10202103015VA SG 10202103015V A SG10202103015V A SG 10202103015VA
- Authority
- SG
- Singapore
- Prior art keywords
- anduses
- toxin
- alpha
- antibody specific
- staphylococcal aureus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56938—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/305—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F)
- G01N2333/31—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
- G01N2333/3156—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062994744P | 2020-03-25 | 2020-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202103015VA true SG10202103015VA (en) | 2021-10-28 |
Family
ID=75223147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202103015V SG10202103015VA (en) | 2020-03-25 | 2021-03-24 | Antibody specific to alpha-toxin of staphylococcal aureus anduses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11530256B2 (en) |
| EP (1) | EP3895762A3 (en) |
| JP (1) | JP2021155416A (en) |
| KR (1) | KR20210119913A (en) |
| CN (4) | CN113444171A (en) |
| BR (1) | BR102021005680A2 (en) |
| SG (1) | SG10202103015VA (en) |
| TW (1) | TW202202519A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117106077A (en) * | 2022-04-28 | 2023-11-24 | 珠海泰诺麦博制药股份有限公司 | Fully human monoclonal antibodies that specifically bind to staphylococcus aureus Hla toxin |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| DK0814159T3 (en) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgenic, non-human animals capable of forming heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| EP2284193A1 (en) | 2009-08-10 | 2011-02-16 | Kenta Biotech AG | Human monoclonal antibody against S. aureus derived apha-toxin and its use in treating or preventing abscess formation |
| CA2826566C (en) | 2011-02-08 | 2022-09-13 | Medimmune, Llc | Antibodies that specifically bind staphylococcus aureus alpha toxin and methods of use |
| US20140286960A1 (en) | 2011-07-28 | 2014-09-25 | Cangene Corporation | Staphlococcus aureus alpha-hemolysin antibodies |
| WO2013093693A1 (en) | 2011-12-22 | 2013-06-27 | Rinat Neuroscience Corp. | Staphylococcus aureus specific antibodies and uses thereof |
| WO2016044588A1 (en) | 2014-09-19 | 2016-03-24 | The Regents Of The University Of Michigan | Staphylococcus aureus materials and methods |
| TW202311284A (en) | 2017-01-03 | 2023-03-16 | 美商再生元醫藥公司 | Human antibodies to s. aureus hemolysin a toxin |
| CN109384844B (en) | 2017-08-04 | 2020-12-18 | 中国人民解放军军事医学科学院基础医学研究所 | Anti-staphylococcus aureus alpha hemolysin monoclonal antibody and application thereof |
| CN109400704B (en) | 2018-11-14 | 2020-07-21 | 珠海泰诺麦博生物技术有限公司 | Antibody against staphylococcus aureus α -hemolysin and application thereof |
| US11345744B2 (en) | 2019-05-07 | 2022-05-31 | William R Church | Antibody specific to Staphylococcus aureus, therapeutic method and detection method using same |
| CN110437334B (en) | 2019-07-26 | 2020-12-01 | 西南医科大学 | Fully human alpha-hemolysin recombinant antibody against staphylococcus aureus |
-
2020
- 2020-07-10 CN CN202010663921.1A patent/CN113444171A/en active Pending
- 2020-07-10 CN CN202010664920.9A patent/CN113444173A/en active Pending
- 2020-07-10 CN CN202010664832.9A patent/CN113444172A/en active Pending
-
2021
- 2021-03-24 BR BR102021005680-0A patent/BR102021005680A2/en unknown
- 2021-03-24 US US17/211,506 patent/US11530256B2/en active Active
- 2021-03-24 SG SG10202103015V patent/SG10202103015VA/en unknown
- 2021-03-25 KR KR1020210038878A patent/KR20210119913A/en unknown
- 2021-03-25 TW TW110110856A patent/TW202202519A/en unknown
- 2021-03-25 EP EP21164842.3A patent/EP3895762A3/en active Pending
- 2021-03-25 JP JP2021051904A patent/JP2021155416A/en active Pending
- 2021-03-25 CN CN202110321155.5A patent/CN113444174A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR102021005680A2 (en) | 2022-03-08 |
| CN113444171A (en) | 2021-09-28 |
| EP3895762A3 (en) | 2022-01-12 |
| CN113444172A (en) | 2021-09-28 |
| US20210317193A1 (en) | 2021-10-14 |
| US11530256B2 (en) | 2022-12-20 |
| JP2021155416A (en) | 2021-10-07 |
| KR20210119913A (en) | 2021-10-06 |
| CN113444174A (en) | 2021-09-28 |
| CN113444173A (en) | 2021-09-28 |
| EP3895762A2 (en) | 2021-10-20 |
| TW202202519A (en) | 2022-01-16 |
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