SG10202101365TA - Integrated microfluidic system for culturing and testing - Google Patents
Integrated microfluidic system for culturing and testingInfo
- Publication number
- SG10202101365TA SG10202101365TA SG10202101365TA SG10202101365TA SG10202101365TA SG 10202101365T A SG10202101365T A SG 10202101365TA SG 10202101365T A SG10202101365T A SG 10202101365TA SG 10202101365T A SG10202101365T A SG 10202101365TA SG 10202101365T A SG10202101365T A SG 10202101365TA
- Authority
- SG
- Singapore
- Prior art keywords
- culturing
- testing
- microfluidic system
- integrated microfluidic
- integrated
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/565—Seals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/02—Membranes; Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/08—Chemical, biochemical or biological means, e.g. plasma jet, co-culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/10—Means to control humidity and/or other gases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physiology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Fluid Mechanics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Thermal Sciences (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG10201606627QA SG10201606627QA (en) | 2016-08-10 | 2016-08-10 | Microfluidic chip |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202101365TA true SG10202101365TA (en) | 2021-03-30 |
Family
ID=61163265
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201606627QA SG10201606627QA (en) | 2016-08-10 | 2016-08-10 | Microfluidic chip |
SG11201901135PA SG11201901135PA (en) | 2016-08-10 | 2017-08-10 | Integrated microfluidic system for culturing and testing |
SG10202101365TA SG10202101365TA (en) | 2016-08-10 | 2017-08-10 | Integrated microfluidic system for culturing and testing |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201606627QA SG10201606627QA (en) | 2016-08-10 | 2016-08-10 | Microfluidic chip |
SG11201901135PA SG11201901135PA (en) | 2016-08-10 | 2017-08-10 | Integrated microfluidic system for culturing and testing |
Country Status (5)
Country | Link |
---|---|
US (1) | US11566212B2 (en) |
EP (1) | EP3496858A4 (en) |
CN (2) | CN109789406A (en) |
SG (3) | SG10201606627QA (en) |
WO (1) | WO2018030958A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL425107A1 (en) * | 2018-03-30 | 2019-10-07 | Bacteromic Spółka Z Ograniczoną Odpowiedzialnością | Incubation section |
GB201816911D0 (en) * | 2018-10-17 | 2018-11-28 | Univ London Queen Mary | Apparatus and methods |
AU2020286511A1 (en) * | 2019-06-07 | 2021-12-16 | Isolation Bio Inc. | Loading and sealing sample on microfabricated chip |
CN112300929B (en) * | 2019-07-31 | 2022-12-02 | 上海新微技术研发中心有限公司 | Microfluidic experiment plate and double-sided cell culture method |
CN112300930A (en) * | 2019-07-31 | 2021-02-02 | 上海新微技术研发中心有限公司 | Microfluidic experimental plate and double-sided cell culture method |
US20220266247A1 (en) * | 2019-08-29 | 2022-08-25 | Astraveus | Apparatus and method for clamping a microfluidic device |
KR102313280B1 (en) * | 2019-12-09 | 2021-10-14 | 조지아 테크 리서치 코오포레이션 | Microengineered tissue barrier system |
EP3854868A1 (en) * | 2020-01-24 | 2021-07-28 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO | Microfluidic device for analyzing a membrane |
MX2020007751A (en) * | 2020-07-21 | 2022-01-24 | Inst Tecnologico Estudios Superiores Monterrey | An insert based on a resealable organ on a chip platform. |
IT202000021847A1 (en) * | 2020-09-16 | 2022-03-16 | React4Life S R L | DEVICE FOR PERFORMING IN VITRO EXPERIMENTS ON BIOLOGICAL MATERIAL |
WO2022112968A1 (en) * | 2020-11-25 | 2022-06-02 | Association For The Advancement Of Tissue Engineering And Cell Based Technologies & Therapies (A4Tec) - Associação | Bioreactor for tissue engineering of multi-tissue structure and manufacturing method thereof |
CN112481077B (en) * | 2020-12-01 | 2022-11-08 | 北京理工大学 | Microfluidic perfusion culture device and perfusion method thereof |
CN113926498B (en) * | 2021-11-04 | 2022-11-29 | 田甜 | Preparation method of laminar flow low-shear force micro-fluidic chip capable of promoting brain-like organ maturation |
WO2023099898A1 (en) * | 2021-12-01 | 2023-06-08 | Microfluidx Ltd | Systems and methods for bioprocessing |
CN116408160A (en) * | 2021-12-31 | 2023-07-11 | 彩科(苏州)生物科技有限公司 | Microfluidic device with stable isolation environment |
WO2023147356A1 (en) * | 2022-01-26 | 2023-08-03 | Nighthawk Biosciences, Inc | Cell deactivation device |
GB202205709D0 (en) * | 2022-04-19 | 2022-06-01 | Keratify Ltd | Biological culture unit |
WO2023218024A1 (en) * | 2022-05-13 | 2023-11-16 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for automated and dynamic cell culture |
CN114832874B (en) * | 2022-05-18 | 2023-06-16 | 厦门大学 | Organ chip, integrated module and system thereof, preparation method and application |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2014220A (en) * | 1933-06-02 | 1935-09-10 | Gen Electric | Electric incandescent lamp and similar device |
US7288405B2 (en) * | 2001-04-25 | 2007-10-30 | Cornell Research Foundation, Inc. | Devices and methods for pharmacokinetic-based cell culture system |
WO2003093406A2 (en) | 2002-05-01 | 2003-11-13 | Massachusetts Institute Of Technology | Microfermentors for rapid screening and analysis of biochemical processes |
DE20312088U1 (en) * | 2003-08-05 | 2004-12-16 | Ibidi Gmbh | Flow chamber for molecules and macromolecules and cells, for study under light with a microscope or spectrometer, has a structured base plate to form a closed channel with a transparent film on the under side |
KR100870982B1 (en) | 2007-05-03 | 2008-12-01 | 주식회사 바이오트론 | A multilayer Bio-reactor |
DE112010005887T5 (en) * | 2010-09-17 | 2013-09-12 | Agency For Science, Technology And Research | Microfluidic device for modifying a fluid flow and microfluidic system with the microfluidic device |
US20140335496A1 (en) * | 2011-12-05 | 2014-11-13 | Research Triangle Institute | Human conducting airway model comprising multiple fluidic pathways |
US20130295551A1 (en) | 2012-03-29 | 2013-11-07 | The Board Of Trustees Of The University Of Illinois | Microfluidic device and method for modulating a gas environment of cell cultures and tissues |
US10900023B2 (en) * | 2013-08-22 | 2021-01-26 | University of Pittsburgh—of the Commonwealth System of Higher Education | Modular, microfluidic, mechanically active bioreactor for 3D, multi-tissue, tissue culture |
CN103451090A (en) * | 2013-09-18 | 2013-12-18 | 上海理工大学 | Micro-fluid cell processing chip and application method thereof |
CN104877905A (en) * | 2015-05-04 | 2015-09-02 | 清华大学深圳研究生院 | Cell in-vitro co-culture microfluidic chip, system and method |
-
2016
- 2016-08-10 SG SG10201606627QA patent/SG10201606627QA/en unknown
-
2017
- 2017-08-10 CN CN201780049385.2A patent/CN109789406A/en active Pending
- 2017-08-10 EP EP17839932.5A patent/EP3496858A4/en active Pending
- 2017-08-10 SG SG11201901135PA patent/SG11201901135PA/en unknown
- 2017-08-10 US US16/324,571 patent/US11566212B2/en active Active
- 2017-08-10 SG SG10202101365TA patent/SG10202101365TA/en unknown
- 2017-08-10 CN CN202210478452.5A patent/CN114887675A/en active Pending
- 2017-08-10 WO PCT/SG2017/050400 patent/WO2018030958A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG11201901135PA (en) | 2019-03-28 |
SG10201606627QA (en) | 2018-03-28 |
CN109789406A (en) | 2019-05-21 |
CN114887675A (en) | 2022-08-12 |
EP3496858A4 (en) | 2020-04-01 |
US20190177678A1 (en) | 2019-06-13 |
EP3496858A1 (en) | 2019-06-19 |
US11566212B2 (en) | 2023-01-31 |
WO2018030958A1 (en) | 2018-02-15 |
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