SG10202101105XA - Charged depth filtration of antigen-binding proteins - Google Patents

Charged depth filtration of antigen-binding proteins

Info

Publication number
SG10202101105XA
SG10202101105XA SG10202101105XA SG10202101105XA SG10202101105XA SG 10202101105X A SG10202101105X A SG 10202101105XA SG 10202101105X A SG10202101105X A SG 10202101105XA SG 10202101105X A SG10202101105X A SG 10202101105XA SG 10202101105X A SG10202101105X A SG 10202101105XA
Authority
SG
Singapore
Prior art keywords
antigen
binding proteins
depth filtration
charged depth
charged
Prior art date
Application number
SG10202101105XA
Inventor
Hai Hoang
Rafael Gonzalez
Junfen Ma
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56802689&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10202101105X(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG10202101105XA publication Critical patent/SG10202101105XA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
SG10202101105XA 2015-08-13 2016-08-12 Charged depth filtration of antigen-binding proteins SG10202101105XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562204831P 2015-08-13 2015-08-13

Publications (1)

Publication Number Publication Date
SG10202101105XA true SG10202101105XA (en) 2021-03-30

Family

ID=56802689

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10202101105XA SG10202101105XA (en) 2015-08-13 2016-08-12 Charged depth filtration of antigen-binding proteins

Country Status (15)

Country Link
US (2) US11098079B2 (en)
EP (2) EP4209499A1 (en)
JP (1) JP6889149B2 (en)
DK (1) DK3334747T3 (en)
ES (1) ES2964640T3 (en)
FI (1) FI3334747T3 (en)
HR (1) HRP20231544T1 (en)
HU (1) HUE064252T2 (en)
LT (1) LT3334747T (en)
MA (1) MA42613A (en)
PL (1) PL3334747T3 (en)
PT (1) PT3334747T (en)
SG (1) SG10202101105XA (en)
SI (1) SI3334747T1 (en)
WO (1) WO2017027861A1 (en)

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US20160257754A1 (en) 2013-10-16 2016-09-08 Momenta Pharmaceuticals Inc. Sialylated glycoproteins
JP2020502218A (en) 2016-12-21 2020-01-23 メレオ バイオファーマ ３ リミテッド Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta
CN107973487B (en) * 2017-11-14 2021-03-02 东华大学 Dyeing and finishing wastewater hierarchical treatment process and device
JP7137696B2 (en) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド Methods and compositions for preventing type 1 diabetes
TW202140511A (en) * 2020-01-15 2021-11-01 瑞士商赫孚孟拉羅股份公司 Methods to decrease impurities from recombinant protein manufacturing processes
CN111410688A (en) * 2020-03-13 2020-07-14 苏州智享众创孵化管理有限公司 Separation and purification method for improving purity of bispecific antibody

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Also Published As

Publication number Publication date
FI3334747T3 (en) 2023-11-30
JP2018526357A (en) 2018-09-13
HUE064252T2 (en) 2024-02-28
SI3334747T1 (en) 2024-02-29
US20180230180A1 (en) 2018-08-16
EP3334747A1 (en) 2018-06-20
PL3334747T3 (en) 2024-04-02
US20210363180A1 (en) 2021-11-25
EP4209499A1 (en) 2023-07-12
US11098079B2 (en) 2021-08-24
DK3334747T3 (en) 2023-12-11
EP3334747B1 (en) 2023-09-27
PT3334747T (en) 2023-12-12
LT3334747T (en) 2023-12-27
HRP20231544T1 (en) 2024-03-15
MA42613A (en) 2018-06-20
ES2964640T3 (en) 2024-04-08
WO2017027861A1 (en) 2017-02-16
JP6889149B2 (en) 2021-06-18

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