SG10202002899VA - Solid pharmaceutical compositions for treating hcv - Google Patents

Solid pharmaceutical compositions for treating hcv

Info

Publication number
SG10202002899VA
SG10202002899VA SG10202002899VA SG10202002899VA SG10202002899VA SG 10202002899V A SG10202002899V A SG 10202002899VA SG 10202002899V A SG10202002899V A SG 10202002899VA SG 10202002899V A SG10202002899V A SG 10202002899VA SG 10202002899V A SG10202002899V A SG 10202002899VA
Authority
SG
Singapore
Prior art keywords
pharmaceutical compositions
solid pharmaceutical
treating hcv
hcv
treating
Prior art date
Application number
SG10202002899VA
Inventor
Nancy Sever
Ulrich Westedt
Ute Lander
Katrin Schneider
Benedikt Steitz
Thomas Mueller
Regina Reul
Constanze Obermiller
Adivaraha Jayasankar
Michael Simon
Yi Gao
Harald Hach
Samuel Kyeremateng
Katharina Asmus
Ping Tong
Donghua Zhu
Marius Naris
Colleen Garrett
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of SG10202002899VA publication Critical patent/SG10202002899VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10202002899VA 2015-06-26 2016-06-24 Solid pharmaceutical compositions for treating hcv SG10202002899VA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562185145P 2015-06-26 2015-06-26
US201562186154P 2015-06-29 2015-06-29
US201562193639P 2015-07-17 2015-07-17
US201662295309P 2016-02-15 2016-02-15

Publications (1)

Publication Number Publication Date
SG10202002899VA true SG10202002899VA (en) 2020-05-28

Family

ID=56409187

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10202002899VA SG10202002899VA (en) 2015-06-26 2016-06-24 Solid pharmaceutical compositions for treating hcv

Country Status (24)

Country Link
US (3) US20160375087A1 (en)
EP (1) EP3313378A1 (en)
JP (2) JP7162425B2 (en)
KR (1) KR102637828B1 (en)
CN (1) CN107920996A (en)
AU (1) AU2016283018C1 (en)
BR (1) BR112017028185A2 (en)
CA (1) CA2990855A1 (en)
CL (1) CL2017003350A1 (en)
CO (1) CO2017013305A2 (en)
CR (1) CR20180030A (en)
DO (1) DOP2017000314A (en)
EA (1) EA201890160A1 (en)
EC (1) ECSP18000689A (en)
HK (1) HK1250627A1 (en)
IL (1) IL256504B (en)
MX (1) MX2018000218A (en)
MY (1) MY192606A (en)
PE (1) PE20180488A1 (en)
PH (1) PH12017502426A1 (en)
RU (2) RU2018102809A (en)
SG (1) SG10202002899VA (en)
WO (1) WO2016210273A1 (en)
ZA (1) ZA201800533B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160375017A1 (en) 2015-06-26 2016-12-29 Abbvie Inc. Solid Pharmaceutical Compositions for Treating HCV
CN108024964B (en) * 2015-07-17 2022-05-03 艾伯维公司 Solid pharmaceutical composition for the treatment of HCV
GB202113944D0 (en) * 2021-09-29 2021-11-10 Univ Liverpool Injectable formulations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087386A (en) * 1996-06-24 2000-07-11 Merck & Co., Inc. Composition of enalapril and losartan
DE102004008804A1 (en) * 2004-02-20 2005-09-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Multilayer tablet
ES2300188B1 (en) * 2006-05-24 2009-05-01 Ferrer Internacional, S.A. BICAPA COMPRESSED FOR THE PREVENTION OF CARDIOVASCULAR ACCIDENTS.
ES2414934T3 (en) * 2009-06-11 2013-07-23 Abbvie Bahamas Limited Hepatitis C virus inhibitors
US9394279B2 (en) * 2009-06-11 2016-07-19 Abbvie Inc. Anti-viral compounds
US8716454B2 (en) * 2009-06-11 2014-05-06 Abbvie Inc. Solid compositions
ES2689107T3 (en) * 2009-11-13 2018-11-08 Astrazeneca Ab Bilayer tablet formulations
NZ605440A (en) * 2010-06-10 2014-05-30 Abbvie Bahamas Ltd Solid compositions comprising an hcv inhibitor
NZ608720A (en) 2010-09-21 2015-03-27 Enanta Pharm Inc Macrocyclic proline derived hcv serine protease inhibitors
EP3597190A1 (en) * 2012-09-18 2020-01-22 AbbVie Inc. Methods for treating hepatitis c
RS60881B1 (en) * 2013-03-14 2020-11-30 Abbvie Inc Combination of two antivirals for treating hepatitis c

Also Published As

Publication number Publication date
KR20180021840A (en) 2018-03-05
IL256504A (en) 2018-02-28
AU2016283018C1 (en) 2022-03-03
EP3313378A1 (en) 2018-05-02
JP2022177014A (en) 2022-11-30
CR20180030A (en) 2018-05-24
PH12017502426A1 (en) 2018-07-02
KR102637828B1 (en) 2024-02-20
CL2017003350A1 (en) 2018-06-22
CO2017013305A2 (en) 2018-05-21
JP2018518517A (en) 2018-07-12
CN107920996A (en) 2018-04-17
RU2018102809A (en) 2019-07-29
RU2021102950A (en) 2021-03-01
RU2018102809A3 (en) 2019-12-10
ECSP18000689A (en) 2018-03-31
CA2990855A1 (en) 2016-12-29
MX2018000218A (en) 2018-03-08
AU2016283018A1 (en) 2018-01-25
BR112017028185A2 (en) 2018-09-04
JP7162425B2 (en) 2022-10-28
ZA201800533B (en) 2018-12-19
US20200282004A1 (en) 2020-09-10
AU2016283018B2 (en) 2021-10-07
PE20180488A1 (en) 2018-03-07
IL256504B (en) 2021-09-30
WO2016210273A1 (en) 2016-12-29
DOP2017000314A (en) 2018-02-15
US20190216882A1 (en) 2019-07-18
US20160375087A1 (en) 2016-12-29
EA201890160A1 (en) 2018-06-29
HK1250627A1 (en) 2019-01-11
MY192606A (en) 2022-08-29

Similar Documents

Publication Publication Date Title
IL290823A (en) Pharmaceutical compositions for combination therapy
IL268316B (en) Pharmaceutical compositions for combination therapy
HK1253720A1 (en) Pharmaceutical compositions for anesthesiological applications
GB201608323D0 (en) Pharmaceutical compositions
HK1254573A1 (en) Pharmaceutical compositions comprising phenylaminopyrimidine derivative
GB201521462D0 (en) Pharmaceutical composition
HK1250627A1 (en) Solid pharmaceutical compositions for treating hcv
HK1250491A1 (en) Stabilized pharmaceutical composition
HK1245073A1 (en) Pharmaceutical compositions
GB201515310D0 (en) Pharmaceutical composition
ZA201703115B (en) Long acting pharmaceutical compositions for hepatitis c
HK1255203A1 (en) Solid pharmaceutical compositions for treating hcv
GB201520862D0 (en) Pharmaceutical composition
IL263999A (en) Pharmaceutical compositions
ZA201705782B (en) Pharmaceutical compositions
ZA201705783B (en) Pharmaceutical compositions
GB201700831D0 (en) Pharmaceutical compositions
PT3319596T (en) Pharmaceutical compositions
GB201608393D0 (en) Solid pharmaceutical compositions
GB201521456D0 (en) Pharmaceutical composition
GB201520762D0 (en) Novel pharmaceutical compositions
GB201506598D0 (en) Pharmaceutical compositions
GB201516183D0 (en) Novel pharmaceutical composition