SG10202000731WA - Nucleic acid sequence assembly - Google Patents

Nucleic acid sequence assembly

Info

Publication number
SG10202000731WA
SG10202000731WA SG10202000731WA SG10202000731WA SG10202000731WA SG 10202000731W A SG10202000731W A SG 10202000731WA SG 10202000731W A SG10202000731W A SG 10202000731WA SG 10202000731W A SG10202000731W A SG 10202000731WA SG 10202000731W A SG10202000731W A SG 10202000731WA
Authority
SG
Singapore
Prior art keywords
nucleic acid
acid sequence
sequence assembly
assembly
nucleic
Prior art date
Application number
SG10202000731WA
Inventor
Nicholas H Putnam
Jonathan C Stites
Brandon J Rice
Original Assignee
Dovetail Genomics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dovetail Genomics Llc filed Critical Dovetail Genomics Llc
Publication of SG10202000731WA publication Critical patent/SG10202000731WA/en

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Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/20Sequence assembly

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG10202000731WA 2015-02-17 2016-02-17 Nucleic acid sequence assembly SG10202000731WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562117256P 2015-02-17 2015-02-17
US201662294208P 2016-02-11 2016-02-11

Publications (1)

Publication Number Publication Date
SG10202000731WA true SG10202000731WA (en) 2020-03-30

Family

ID=55587335

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202000731WA SG10202000731WA (en) 2015-02-17 2016-02-17 Nucleic acid sequence assembly
SG11201706730XA SG11201706730XA (en) 2015-02-17 2016-02-17 Nucleic acid sequence assembly

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201706730XA SG11201706730XA (en) 2015-02-17 2016-02-17 Nucleic acid sequence assembly

Country Status (11)

Country Link
US (4) US9715573B2 (en)
EP (2) EP4030437A1 (en)
JP (2) JP6777966B2 (en)
KR (1) KR20170134379A (en)
CN (1) CN107533590B (en)
AU (1) AU2016220135B2 (en)
CA (1) CA2976902A1 (en)
IL (1) IL254000B (en)
NZ (1) NZ734854A (en)
SG (2) SG10202000731WA (en)
WO (1) WO2016134034A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2956925C (en) 2014-08-01 2024-02-13 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
SG10202000731WA (en) 2015-02-17 2020-03-30 Dovetail Genomics Llc Nucleic acid sequence assembly
US11807896B2 (en) 2015-03-26 2023-11-07 Dovetail Genomics, Llc Physical linkage preservation in DNA storage
EP3317420B1 (en) 2015-07-02 2021-10-20 Arima Genomics, Inc. Accurate molecular deconvolution of mixtures samples
WO2017070123A1 (en) 2015-10-19 2017-04-27 Dovetail Genomics, Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
KR20180116377A (en) 2016-02-23 2018-10-24 더브테일 제노믹스 엘엘씨 Generation and Hexagonal Paging of a Paged Read Set for Genome Assemblies
KR102412442B1 (en) 2016-05-13 2022-06-22 더브테일 제노믹스 엘엘씨 Retrieval of long-range linkage information from preserved samples
EP3507297A4 (en) * 2016-09-02 2020-05-27 Ludwig Institute for Cancer Research Ltd Genome-wide identification of chromatin interactions
AU2018366198A1 (en) * 2017-11-09 2020-05-28 Dovetail Genomics, Llc Structural variant analysis
EP3743102A1 (en) 2018-01-26 2020-12-02 Nantcell, Inc. Compositions and methods for combination cancer vaccine and immunologic adjuvant therapy
WO2019147921A1 (en) 2018-01-26 2019-08-01 Nantcell, Inc. Rapid verification of virus particle production for a personalized vaccine
EP3746566A1 (en) 2018-01-31 2020-12-09 Dovetail Genomics, LLC Sample prep for dna linkage recovery
CN108460248B (en) * 2018-03-08 2022-02-22 北京希望组生物科技有限公司 Method for detecting long tandem repeat sequence based on Bionano platform
CN108897986B (en) * 2018-05-29 2020-11-27 中南大学 Genome sequence splicing method based on protein information
JP7361774B2 (en) * 2018-07-27 2023-10-16 ミリアド・ウィメンズ・ヘルス・インコーポレーテッド A method for detecting genetic variation in highly homologous sequences by independent alignment and pairing of sequence reads
US20200075123A1 (en) * 2018-08-31 2020-03-05 Guardant Health, Inc. Genetic variant detection based on merged and unmerged reads
CN109273052B (en) * 2018-09-13 2022-03-18 北京百迈客生物科技有限公司 Genome haploid assembling method and device
WO2020154630A1 (en) * 2019-01-25 2020-07-30 Pacific Biosciences Of California, Inc. Systems and methods for graph based mapping of nucleic acid fragments
CN115349128A (en) 2020-02-13 2022-11-15 齐默尔根公司 Metagenomic libraries and natural product discovery platform
CN116759132A (en) * 2023-04-17 2023-09-15 南京大学 DNA molecular wire and use thereof

Family Cites Families (144)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (en) 1970-11-10 1977-09-15 Organon Nv PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5242794A (en) 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
ATE199054T1 (en) 1990-12-06 2001-02-15 Affymetrix Inc A Delaware Corp COMPOUNDS AND THEIR USE IN A BINARY SYNTHESIS STRATEGY
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP0972564B1 (en) 1991-11-22 2003-05-28 Affymetrix, Inc. (a Delaware Corporation) Method of forming arrays of polymers
US6033854A (en) 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5567583A (en) 1991-12-16 1996-10-22 Biotronics Corporation Methods for reducing non-specific priming in DNA detection
US5348853A (en) 1991-12-16 1994-09-20 Biotronics Corporation Method for reducing non-specific priming in DNA amplification
ATE246702T1 (en) 1993-04-12 2003-08-15 Univ Northwestern METHOD FOR PREPARING OLIGONUCLEOTIDES
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
AU8126694A (en) 1993-10-26 1995-05-22 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US6110709A (en) 1994-03-18 2000-08-29 The General Hospital Corporation Cleaved amplified modified polymorphic sequence detection methods
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5705628A (en) 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5599695A (en) 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
US5780613A (en) 1995-08-01 1998-07-14 Northwestern University Covalent lock for self-assembled oligonucleotide constructs
WO1997029212A1 (en) 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US5786146A (en) 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
NZ502323A (en) 1996-06-04 2001-09-28 Univ Utah Res Found Monitoring a fluorescence energy transfer pair during hybridization of first probe labelled with fluorescein to second probe labelled with Cy5 or Cy5.5
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6449562B1 (en) 1996-10-10 2002-09-10 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
WO1998041651A1 (en) 1997-03-18 1998-09-24 Hsc Research & Development Limited Partnership Method for preparing chromatin
US6969488B2 (en) 1998-05-22 2005-11-29 Solexa, Inc. System and apparatus for sequential processing of analytes
US6287766B1 (en) 1997-10-28 2001-09-11 The Regents Of The University Of California DNA polymorphism identity determination using flow cytometry
US5989823A (en) 1998-09-18 1999-11-23 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6787308B2 (en) 1998-07-30 2004-09-07 Solexa Ltd. Arrayed biomolecules and their use in sequencing
US20030022207A1 (en) 1998-10-16 2003-01-30 Solexa, Ltd. Arrayed polynucleotides and their use in genome analysis
US20040106110A1 (en) 1998-07-30 2004-06-03 Solexa, Ltd. Preparation of polynucleotide arrays
JP2002524091A (en) 1998-08-21 2002-08-06 ナックスコー・インコーポレイテッド Assays using immobilized crosslinkable nucleic acids
DK1137812T3 (en) 1998-12-02 2007-05-21 Adnexus Therapeutics Inc DNA-protein fusions and uses thereof
US8367322B2 (en) 1999-01-06 2013-02-05 Cornell Research Foundation, Inc. Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing
US6994969B1 (en) 1999-04-30 2006-02-07 Methexis Genomics, N.V. Diagnostic sequencing by a combination of specific cleavage and mass spectrometry
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US6225109B1 (en) 1999-05-27 2001-05-01 Orchid Biosciences, Inc. Genetic analysis device
US7211390B2 (en) 1999-09-16 2007-05-01 454 Life Sciences Corporation Method of sequencing a nucleic acid
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
WO2001023610A2 (en) 1999-09-29 2001-04-05 Solexa Ltd. Polynucleotide sequencing
US6582938B1 (en) 2001-05-11 2003-06-24 Affymetrix, Inc. Amplification of nucleic acids
GB0002389D0 (en) 2000-02-02 2000-03-22 Solexa Ltd Molecular arrays
US6448717B1 (en) 2000-07-17 2002-09-10 Micron Technology, Inc. Method and apparatuses for providing uniform electron beams from field emission displays
WO2002027029A2 (en) 2000-09-27 2002-04-04 Lynx Therapeutics, Inc. Method for determining relative abundance of nucleic acid sequences
US7001724B1 (en) 2000-11-28 2006-02-21 Applera Corporation Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases
WO2002079502A1 (en) 2001-03-28 2002-10-10 The University Of Queensland A method for nucleic acid sequence analysis
DE10120797B4 (en) 2001-04-27 2005-12-22 Genovoxx Gmbh Method for analyzing nucleic acid chains
GB0114853D0 (en) 2001-06-18 2001-08-08 Medical Res Council Happier Mapping
DE10239504A1 (en) 2001-08-29 2003-04-24 Genovoxx Gmbh Parallel sequencing of nucleic acid fragments, useful e.g. for detecting mutations, comprises sequential single-base extension of immobilized fragment-primer complex
DE10246005A1 (en) 2001-10-04 2003-04-30 Genovoxx Gmbh Automated nucleic acid sequencer, useful e.g. for analyzing gene expression, based on parallel incorporation of fluorescently labeled terminating nucleotides
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US20050124022A1 (en) 2001-10-30 2005-06-09 Maithreyan Srinivasan Novel sulfurylase-luciferase fusion proteins and thermostable sulfurylase
CA2465588A1 (en) 2001-11-09 2003-05-22 Aclara Biosciences, Inc. Detection of nucleic acid sequences by cleavage and separation of tag-containing structures
US20050130161A1 (en) 2002-03-08 2005-06-16 Peter Fraser Tagging and recovery of elements associated with target molecules
US20030228627A1 (en) 2002-03-22 2003-12-11 Emerson Beverly M. Assay for p53 function in cells
EP1534859B1 (en) 2002-06-28 2010-11-24 PrimeraDx, Inc. Methods of detecting sequence differences
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
US7414117B2 (en) 2002-12-26 2008-08-19 Ngk Insulators, Ltd. Nucleotide derivative and DNA microarray
CA2727850C (en) 2003-01-29 2013-04-30 454 Corporation Methods of amplifying and sequencing nucleic acids
US20040197779A1 (en) 2003-04-03 2004-10-07 Apffel James Alexander Methods for analyzing mixtures of proteins
US8741577B2 (en) 2003-04-07 2014-06-03 Bio-Rad Laboratories Inc. Surface immobilised multilayer structure of vesicles
FI20030778A0 (en) 2003-05-22 2003-05-22 Licentia Oy Determination or prediction of disease
WO2005001113A2 (en) 2003-06-27 2005-01-06 Thomas Jefferson University Methods for detecting nucleic acid variations
ES2321405T3 (en) 2003-07-02 2009-06-05 Dsm Ip Assets B.V. IMPROVED TEST SYSTEM FOR THE DETERMINATION OF THE PRESENCE OF AN ANTIBIOTIC IN A FLUID.
GB0316075D0 (en) 2003-07-09 2003-08-13 Molecular Sensing Plc Protease detection assay
WO2005044836A2 (en) 2003-11-05 2005-05-19 Genovoxx Gmbh Macromolecular nucleotide compounds and methods for using the same
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
WO2005084272A2 (en) 2004-02-28 2005-09-15 Wang Chang-Ning J Nucleic acid complexes
US20060024711A1 (en) 2004-07-02 2006-02-02 Helicos Biosciences Corporation Methods for nucleic acid amplification and sequence determination
US7361468B2 (en) 2004-07-02 2008-04-22 Affymetrix, Inc. Methods for genotyping polymorphisms in humans
US7276720B2 (en) 2004-07-19 2007-10-02 Helicos Biosciences Corporation Apparatus and methods for analyzing samples
US20060012793A1 (en) 2004-07-19 2006-01-19 Helicos Biosciences Corporation Apparatus and methods for analyzing samples
US20060024678A1 (en) 2004-07-28 2006-02-02 Helicos Biosciences Corporation Use of single-stranded nucleic acid binding proteins in sequencing
GB0422730D0 (en) 2004-10-13 2004-11-17 Lingvitae As Method
US7425415B2 (en) 2005-04-06 2008-09-16 City Of Hope Method for detecting methylated CpG islands
JP2006301289A (en) 2005-04-20 2006-11-02 Tokyo Ohka Kogyo Co Ltd Negative resist composition and resist pattern forming method
US20090233291A1 (en) 2005-06-06 2009-09-17 454 Life Sciences Corporation Paired end sequencing
EP1907583B2 (en) 2005-06-15 2019-10-23 Complete Genomics Inc. Single molecule arrays for genetic and chemical analysis
ES2556113T3 (en) 2005-07-04 2016-01-13 Erasmus University Medical Center Chromosomal conformation chip (4C) capture test
US20110027890A1 (en) 2005-12-26 2011-02-03 Kuraray Co., Ltd. Material for cell culture
US20070172839A1 (en) 2006-01-24 2007-07-26 Smith Douglas R Asymmetrical adapters and methods of use thereof
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
US8071296B2 (en) 2006-03-13 2011-12-06 Agency For Science, Technology And Research Nucleic acid interaction analysis
WO2007136874A2 (en) 2006-05-18 2007-11-29 President And Fellows Of Harvard College Genomic library construction
EP2057282A4 (en) 2006-08-24 2010-10-27 Univ Massachusetts Medical Mapping of genomic interactions
CA2665537A1 (en) 2006-10-04 2008-10-23 Brookhaven Science Associates Dna-guided nanoparticle assemblies
US8278112B2 (en) 2006-12-21 2012-10-02 The Regents Of The University Of California Site-specific installation of methyl-lysine analogues into recombinant histones
DK2121977T3 (en) 2007-01-11 2017-09-18 Erasmus Univ Medical Center Capture (4C) OF CHROMOSOMES WITH CIRCULAR CONFORMATION
WO2008097887A2 (en) 2007-02-02 2008-08-14 Emory University Methods of direct genomic selection using high density oligonucleotide microarrays
AU2008254986A1 (en) 2007-05-14 2008-11-27 Insight Genetics, Inc. Methods of screening nucleic acids for single nucleotide variations
US8951731B2 (en) 2007-10-15 2015-02-10 Complete Genomics, Inc. Sequence analysis using decorated nucleic acids
EP2053132A1 (en) 2007-10-23 2009-04-29 Roche Diagnostics GmbH Enrichment and sequence analysis of geomic regions
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US8263367B2 (en) 2008-01-25 2012-09-11 Agency For Science, Technology And Research Nucleic acid interaction analysis
WO2009132315A1 (en) 2008-04-24 2009-10-29 Life Technologies Corporation Method of sequencing and mapping target nucleic acids
US20090298064A1 (en) 2008-05-29 2009-12-03 Serafim Batzoglou Genomic Sequencing
GB0810051D0 (en) 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
US8076070B2 (en) 2008-08-06 2011-12-13 University Of Southern California Genome-wide chromosome conformation capture
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
CN104372080B (en) 2008-11-18 2018-03-30 博纳基因技术有限公司 polynucleotide mapping and sequencing
CN101504697B (en) * 2008-12-12 2010-09-08 深圳华大基因研究院 Construction method and system for genome sequencing equipment and its fragment connection stand
EP2379751B1 (en) * 2009-01-13 2013-03-20 Keygene N.V. Novel genome sequencing strategies
US8703462B2 (en) 2009-02-03 2014-04-22 New England Biolabs, Inc. Generation of random double-strand breaks in DNA using enzymes
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
CN102858995B (en) 2009-09-10 2016-10-26 森特瑞隆技术控股公司 Targeting sequence measurement
US10207240B2 (en) 2009-11-03 2019-02-19 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
US20110287947A1 (en) 2010-05-18 2011-11-24 University Of Southern California Tethered Conformation Capture
WO2012005595A2 (en) 2010-07-09 2012-01-12 Wouter Leonard De Laat V3-d genomic region of interest sequencing strategies
WO2012047726A1 (en) 2010-09-29 2012-04-12 The Broad Institute, Inc. Methods for chromatin immuno-precipitations
EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
US20120197533A1 (en) * 2010-10-11 2012-08-02 Complete Genomics, Inc. Identifying rearrangements in a sequenced genome
HUE039766T2 (en) 2010-10-22 2019-02-28 Cold Spring Harbor Laboratory Varietal counting of nucleic acids for obtaining genomic copy number information
WO2012103442A2 (en) 2011-01-28 2012-08-02 The Broad Institute, Inc. Paired end bead amplification and high throughput sequencing
AU2012212148B8 (en) 2011-02-02 2017-07-06 University Of Washington Through Its Center For Commercialization Massively parallel contiguity mapping
AU2012242525B2 (en) 2011-04-14 2015-09-17 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
EP2705156B1 (en) 2011-05-05 2015-08-26 Institut National de la Santé et de la Recherche Médicale (INSERM) Linear dna amplification
US8663919B2 (en) 2011-05-18 2014-03-04 Life Technologies Corporation Chromosome conformation analysis
EP2710172B1 (en) 2011-05-20 2017-03-29 Fluidigm Corporation Nucleic acid encoding reactions
WO2012177774A2 (en) 2011-06-21 2012-12-27 Life Technologies Corporation Systems and methods for hybrid assembly of nucleic acid sequences
US20140136121A1 (en) * 2011-07-05 2014-05-15 Bgi Tech Solutions Co., Ltd. Method for assembling sequenced segments
WO2013078470A2 (en) 2011-11-22 2013-05-30 MOTIF, Active Multiplex isolation of protein-associated nucleic acids
US10081807B2 (en) 2012-04-24 2018-09-25 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
KR101974577B1 (en) 2012-05-21 2019-05-02 삼성전자주식회사 Template for manufacturing nanoparticle and method for preparing nanoparticle using the same
IL236633B (en) 2012-07-13 2022-07-01 X Chem Inc Dna-encoded libraries comprising a complex having a cross-linking oligonucleotide linkage
WO2014047561A1 (en) 2012-09-21 2014-03-27 The Broad Institute Inc. Compositions and methods for labeling of agents
GB2519255B (en) 2013-02-01 2016-01-06 Univ California Methods for genome assembly and haplotype phasing
US9411930B2 (en) * 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
AU2014362322B2 (en) 2013-12-11 2021-05-27 The Regents For Of The University Of California Methods for labeling DNA fragments to recontruct physical linkage and phase
CA2956925C (en) 2014-08-01 2024-02-13 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
WO2016044313A1 (en) 2014-09-16 2016-03-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for the removal of aldehyde adducts and crosslinks from biomolecules
US11873480B2 (en) 2014-10-17 2024-01-16 Illumina Cambridge Limited Contiguity preserving transposition
SG10202000731WA (en) 2015-02-17 2020-03-30 Dovetail Genomics Llc Nucleic acid sequence assembly
US11807896B2 (en) 2015-03-26 2023-11-07 Dovetail Genomics, Llc Physical linkage preservation in DNA storage
US11434522B1 (en) 2015-06-24 2022-09-06 Oxford BioDynamics PLC Detection of chromosome interactions
WO2017070123A1 (en) 2015-10-19 2017-04-27 Dovetail Genomics, Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection

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CN107533590A (en) 2018-01-02
SG11201706730XA (en) 2017-09-28
NZ734854A (en) 2022-11-25
JP2021007039A (en) 2021-01-21
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