SG10201914030UA - Aminopyrimidines as alk inhibitors - Google Patents
Aminopyrimidines as alk inhibitorsInfo
- Publication number
- SG10201914030UA SG10201914030UA SG10201914030UA SG10201914030UA SG10201914030UA SG 10201914030U A SG10201914030U A SG 10201914030UA SG 10201914030U A SG10201914030U A SG 10201914030UA SG 10201914030U A SG10201914030U A SG 10201914030UA SG 10201914030U A SG10201914030U A SG 10201914030UA
- Authority
- SG
- Singapore
- Prior art keywords
- aminopyrimidines
- alk inhibitors
- alk
- inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662380818P | 2016-08-29 | 2016-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201914030UA true SG10201914030UA (en) | 2020-03-30 |
Family
ID=59846649
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201914030UA SG10201914030UA (en) | 2016-08-29 | 2017-08-28 | Aminopyrimidines as alk inhibitors |
| SG11201901251SA SG11201901251SA (en) | 2016-08-29 | 2017-08-28 | Aminopyrimidines as alk inhibitors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201901251SA SG11201901251SA (en) | 2016-08-29 | 2017-08-28 | Aminopyrimidines as alk inhibitors |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10709705B2 (en) |
| EP (2) | EP3504203B1 (en) |
| JP (2) | JP7094566B2 (en) |
| KR (1) | KR102530871B1 (en) |
| CN (2) | CN115043821A (en) |
| AU (2) | AU2017319135B2 (en) |
| BR (1) | BR112019003897A2 (en) |
| CA (1) | CA3033223A1 (en) |
| IL (1) | IL264638B (en) |
| MX (2) | MX2019002393A (en) |
| NZ (1) | NZ751713A (en) |
| SG (2) | SG10201914030UA (en) |
| WO (1) | WO2018044767A2 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110772638B (en) * | 2018-07-31 | 2021-02-23 | 苏州亚盛药业有限公司 | Application of ALK inhibitor and EGFR inhibitor in preparation of drugs for treating cancers |
| CN111171033B (en) * | 2018-11-09 | 2021-11-02 | 天津大学 | Pyrimidine derivative and synthesis method and application thereof |
| US20220143049A1 (en) | 2019-03-21 | 2022-05-12 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| CN110143947B (en) * | 2019-05-29 | 2021-10-15 | 华东师范大学 | Preparation method of ceritinib analogue |
| WO2020259553A1 (en) * | 2019-06-25 | 2020-12-30 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination of fak inhibitor and btk inhibitor for treating a disease |
| EP4054579A1 (en) | 2019-11-08 | 2022-09-14 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| US20230381176A1 (en) * | 2020-09-25 | 2023-11-30 | Ascentage Pharma (Suzhou) Co., Ltd. | A pharmaceutical composition and use thereof for treatment of cancer |
| WO2022222932A1 (en) * | 2021-04-19 | 2022-10-27 | Ascentage Pharma (Suzhou) Co., Ltd. | A pharmaceutical combination and use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| GB0004888D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0305929D0 (en) * | 2003-03-14 | 2003-04-23 | Novartis Ag | Organic compounds |
| SI1660458T1 (en) | 2003-08-15 | 2012-05-31 | Novartis Ag | 2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders |
| CA2538413A1 (en) * | 2003-09-18 | 2005-03-24 | Novartis Ag | 2,4-di (phenylamino) pyrimidines useful in the treatment of proliferative disorders |
| CN1964970B (en) * | 2004-04-07 | 2011-08-03 | 诺瓦提斯公司 | Inhibitors of iap |
| EP3012249A1 (en) | 2006-12-08 | 2016-04-27 | Novartis AG | Compounds and composition as protein kinase inhibitors |
| EP2271630B1 (en) | 2008-04-07 | 2016-03-23 | Novartis AG | Compounds and compositions as protein kinase inhibitors |
| US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
| BR112013008816A2 (en) | 2010-10-14 | 2016-06-28 | Ariad Pharma Inc | a method of treating egfr cancer targeted to erlotinib or gefitinib resistant or using a pharmaceutically acceptable salt in an individual |
| KR101521861B1 (en) | 2011-02-02 | 2015-05-21 | 노파르티스 아게 | Methods of using alk inhibitors |
| CN104672214B (en) | 2013-12-03 | 2019-04-12 | 上海翰森生物医药科技有限公司 | Compound and its preparation and purposes with ALK inhibitory activity |
| KR101656382B1 (en) | 2014-02-28 | 2016-09-09 | 한국화학연구원 | pyrimidine-2,4-diamine derivatives and pharmaceutical composition for anti cancer containing the same as an active ingredient |
-
2017
- 2017-08-28 NZ NZ751713A patent/NZ751713A/en unknown
- 2017-08-28 CN CN202210533398.XA patent/CN115043821A/en active Pending
- 2017-08-28 EP EP17764949.8A patent/EP3504203B1/en active Active
- 2017-08-28 SG SG10201914030UA patent/SG10201914030UA/en unknown
- 2017-08-28 BR BR112019003897-3A patent/BR112019003897A2/en unknown
- 2017-08-28 MX MX2019002393A patent/MX2019002393A/en unknown
- 2017-08-28 US US15/559,445 patent/US10709705B2/en active Active
- 2017-08-28 CN CN201780057518.0A patent/CN109715620B/en active Active
- 2017-08-28 EP EP21212760.9A patent/EP4001273A3/en not_active Withdrawn
- 2017-08-28 CA CA3033223A patent/CA3033223A1/en active Pending
- 2017-08-28 AU AU2017319135A patent/AU2017319135B2/en active Active
- 2017-08-28 WO PCT/US2017/048845 patent/WO2018044767A2/en unknown
- 2017-08-28 SG SG11201901251SA patent/SG11201901251SA/en unknown
- 2017-08-28 KR KR1020197007075A patent/KR102530871B1/en active IP Right Grant
- 2017-08-28 JP JP2019511664A patent/JP7094566B2/en active Active
-
2019
- 2019-02-04 IL IL264638A patent/IL264638B/en unknown
- 2019-02-27 MX MX2022000376A patent/MX2022000376A/en unknown
-
2020
- 2020-06-29 US US16/914,518 patent/US11110090B2/en active Active
-
2021
- 2021-05-14 AU AU2021203098A patent/AU2021203098B2/en active Active
-
2022
- 2022-06-15 JP JP2022096630A patent/JP2022120151A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018044767A2 (en) | 2018-03-08 |
| IL264638B (en) | 2021-08-31 |
| EP4001273A2 (en) | 2022-05-25 |
| EP4001273A3 (en) | 2022-08-24 |
| AU2021203098A1 (en) | 2021-06-10 |
| JP2022120151A (en) | 2022-08-17 |
| JP7094566B2 (en) | 2022-07-04 |
| BR112019003897A2 (en) | 2019-05-21 |
| US20190175595A1 (en) | 2019-06-13 |
| MX2022000376A (en) | 2022-02-10 |
| EP3504203A2 (en) | 2019-07-03 |
| CN109715620B (en) | 2022-05-06 |
| AU2021203098B2 (en) | 2023-05-25 |
| US20200330464A1 (en) | 2020-10-22 |
| CA3033223A1 (en) | 2018-03-08 |
| SG11201901251SA (en) | 2019-03-28 |
| EP3504203B1 (en) | 2022-09-28 |
| CN115043821A (en) | 2022-09-13 |
| CN109715620A (en) | 2019-05-03 |
| NZ751713A (en) | 2022-07-01 |
| WO2018044767A3 (en) | 2018-04-12 |
| MX2019002393A (en) | 2019-07-08 |
| KR102530871B1 (en) | 2023-05-09 |
| JP2019528307A (en) | 2019-10-10 |
| US11110090B2 (en) | 2021-09-07 |
| AU2017319135B2 (en) | 2021-03-18 |
| US10709705B2 (en) | 2020-07-14 |
| AU2017319135A1 (en) | 2019-04-04 |
| KR20190039760A (en) | 2019-04-15 |
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