SG10201913419TA - Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same - Google Patents

Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same

Info

Publication number
SG10201913419TA
SG10201913419TA SG10201913419TA SG10201913419TA SG10201913419TA SG 10201913419T A SG10201913419T A SG 10201913419TA SG 10201913419T A SG10201913419T A SG 10201913419TA SG 10201913419T A SG10201913419T A SG 10201913419TA SG 10201913419T A SG10201913419T A SG 10201913419TA
Authority
SG
Singapore
Prior art keywords
treating
same
cognitive disorders
preventing cognitive
agent
Prior art date
Application number
SG10201913419TA
Inventor
Hiroshi Eguchi
Takashi Murakami
Naoko Namiki
Akira Tanokura
Jeanne Baker
Batteur Sophie Parmentier
Angela Jablonski
Daniel Stephen Malashock
Carl Mieczkowski
Gopalan Raghunathan (Raghu)
Original Assignee
Teijin Pharma Ltd
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd, Merck Sharp & Dohme filed Critical Teijin Pharma Ltd
Publication of SG10201913419TA publication Critical patent/SG10201913419TA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201913419TA 2017-02-27 2018-02-27 Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same SG10201913419TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017035594A JP2018139530A (en) 2017-02-27 2017-02-27 Humanized antibody for treating or preventing dementia and production method therefor and therapeutic agent or prophylactic agent for dementia using same

Publications (1)

Publication Number Publication Date
SG10201913419TA true SG10201913419TA (en) 2020-03-30

Family

ID=62025891

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913419TA SG10201913419TA (en) 2017-02-27 2018-02-27 Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same
SG11201907548PA SG11201907548PA (en) 2017-02-27 2018-02-27 Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201907548PA SG11201907548PA (en) 2017-02-27 2018-02-27 Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same

Country Status (26)

Country Link
US (3) US10556950B2 (en)
EP (1) EP3585810A1 (en)
JP (3) JP2018139530A (en)
KR (1) KR20190122674A (en)
CN (2) CN110382528A (en)
AR (2) AR110875A1 (en)
AU (1) AU2018224390A1 (en)
BR (1) BR112019016490A2 (en)
CA (1) CA3052538A1 (en)
CL (2) CL2019002296A1 (en)
CO (1) CO2019008786A2 (en)
CR (1) CR20190363A (en)
DO (1) DOP2019000215A (en)
EA (1) EA201991726A1 (en)
GE (1) GEP20227392B (en)
IL (1) IL267945A (en)
JO (1) JOP20180014A1 (en)
MA (1) MA47608A (en)
MX (1) MX2019009945A (en)
MY (1) MY193821A (en)
NI (1) NI201900086A (en)
PE (1) PE20191614A1 (en)
PH (1) PH12019501929A1 (en)
SG (2) SG10201913419TA (en)
TW (1) TW201843179A (en)
WO (2) WO2018154392A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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CN110520440A (en) 2017-02-17 2019-11-29 戴纳立制药公司 Anti- τ antibody and its application method
JOP20180014A1 (en) * 2017-02-27 2019-01-30 Teijin Pharma Ltd Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same
TW202340244A (en) 2017-10-16 2023-10-16 日商衛材R&D企管股份有限公司 Anti-tau antibodies and uses thereof
AU2020325770B2 (en) * 2019-08-06 2022-08-25 Aprinoia Therapeutics Limited Antibodies that bind to pathological tau species and uses thereof
EP4159860A1 (en) * 2020-06-02 2023-04-05 Teijin Pharma Limited Anti-igf-1 receptor humanized antibody
AU2021297873A1 (en) 2020-06-25 2023-02-09 Merck Sharp & Dohme Llc High affinity antibodies targeting tau phosphorylated at serine 413
WO2023092004A1 (en) 2021-11-17 2023-05-25 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

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Also Published As

Publication number Publication date
JOP20180014A1 (en) 2019-01-30
CR20190363A (en) 2019-11-05
KR20190122674A (en) 2019-10-30
CN110382528A (en) 2019-10-25
BR112019016490A2 (en) 2020-04-07
JP2020508666A (en) 2020-03-26
WO2018154392A1 (en) 2018-08-30
MY193821A (en) 2022-10-27
CN111320695A (en) 2020-06-23
JP7165996B2 (en) 2022-11-07
US10894829B2 (en) 2021-01-19
EA201991726A1 (en) 2020-01-30
US20180346564A1 (en) 2018-12-06
MA47608A (en) 2020-01-01
CA3052538A1 (en) 2018-08-30
US11739143B2 (en) 2023-08-29
US20200223916A1 (en) 2020-07-16
EP3585810A1 (en) 2020-01-01
DOP2019000215A (en) 2019-09-30
CN111320695B (en) 2021-09-03
TW201843179A (en) 2018-12-16
JP2023002670A (en) 2023-01-10
PE20191614A1 (en) 2019-11-05
JP2018139530A (en) 2018-09-13
MX2019009945A (en) 2019-11-05
GEP20227392B (en) 2022-06-27
NI201900086A (en) 2019-10-08
WO2018154390A1 (en) 2018-08-30
SG11201907548PA (en) 2019-09-27
AR110875A1 (en) 2019-05-08
US20210380677A1 (en) 2021-12-09
CL2021002389A1 (en) 2022-04-22
CO2019008786A2 (en) 2019-08-20
US10556950B2 (en) 2020-02-11
IL267945A (en) 2019-09-26
PH12019501929A1 (en) 2020-06-29
AU2018224390A1 (en) 2019-07-11
AR117952A2 (en) 2021-09-08
CL2019002296A1 (en) 2019-11-29

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