SG10201900569TA - A microscope module for imaging a sample - Google Patents

A microscope module for imaging a sample

Info

Publication number
SG10201900569TA
SG10201900569TA SG10201900569TA SG10201900569TA SG10201900569TA SG 10201900569T A SG10201900569T A SG 10201900569TA SG 10201900569T A SG10201900569T A SG 10201900569TA SG 10201900569T A SG10201900569T A SG 10201900569TA SG 10201900569T A SG10201900569T A SG 10201900569TA
Authority
SG
Singapore
Prior art keywords
sample
imaging
microscope module
illumination beam
path
Prior art date
Application number
SG10201900569TA
Inventor
Petr Strnad
Lars Hufnagel
Jan Ellenberg
Uros Krzic
Original Assignee
European Molecular Biology Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48288946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201900569T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by European Molecular Biology Laboratory filed Critical European Molecular Biology Laboratory
Publication of SG10201900569TA publication Critical patent/SG10201900569TA/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0088—Inverse microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison

Abstract

OF THE DISCLOSURE A MICROSCOPE MODULE FOR IMAGING A SAMPLE A microscope module (300) for imaging a sample (270) is disclosed. The microscope module (300) comprises at least one illumination objective (210) for producing an illumination beam along an illumination beam path (215) arranged to illuminate lower surface of the sample (270) and at least one detection objective (220) having a detection path (225). The detection path (225) is at an angle to the illumination beam path (215). [Figure 3]
SG10201900569TA 2013-05-10 2014-05-07 A microscope module for imaging a sample SG10201900569TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13167360.0A EP2801855B1 (en) 2013-05-10 2013-05-10 A microscope module for imaging a sample

Publications (1)

Publication Number Publication Date
SG10201900569TA true SG10201900569TA (en) 2019-02-27

Family

ID=48288946

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201600146SA SG11201600146SA (en) 2013-05-10 2014-05-07 A microscope module for imaging a sample
SG10201900569TA SG10201900569TA (en) 2013-05-10 2014-05-07 A microscope module for imaging a sample

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201600146SA SG11201600146SA (en) 2013-05-10 2014-05-07 A microscope module for imaging a sample

Country Status (7)

Country Link
US (4) US9946057B2 (en)
EP (2) EP3605183A1 (en)
JP (2) JP6445531B2 (en)
CN (2) CN105190399B (en)
HK (1) HK1218671A1 (en)
SG (2) SG11201600146SA (en)
WO (1) WO2014180884A1 (en)

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US10139608B2 (en) 2014-10-02 2018-11-27 The Regents Of The University Of California Selective plane illumination microscopy (SPIM) systems and methods
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WO2016178856A1 (en) * 2015-05-01 2016-11-10 The Board Of Regents Of The University Of Texas System Uniform and scalable light-sheets generated by extended focusing
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US10876970B2 (en) 2016-04-12 2020-12-29 The Board Of Regents Of The University Of Texas System Light-sheet microscope with parallelized 3D image acquisition
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US10310248B2 (en) * 2016-08-18 2019-06-04 Olympus Corporation Microscope including a medium container containing an immersion medium in which a specimen container containing an immersion medium and a sample is immersed
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US20200278525A1 (en) 2017-11-10 2020-09-03 Viventis Microscopy Sàrl Microscope for imaging a sample and sample holder for such a microscope
CN108020503B (en) * 2017-11-20 2020-09-08 苏州博芮恩光电科技有限公司 Light sheet illumination microscopic section imaging system and imaging result processing method
US11092793B2 (en) * 2017-11-30 2021-08-17 Fondazione Istituto Italiano Di Tecnologia Method of lightening at least one biological sample, three-dimensional high resolution depletion microscopy method and corresponding microscope
DE102018221670A1 (en) * 2018-12-13 2020-06-18 Karlsruher Institut für Technologie Device and method for the optical characterization or processing of an object
WO2020120102A1 (en) * 2018-12-14 2020-06-18 Johann Wolfgang Goethe-Universität Frankfurt am Main Attachment for an immersion objective
EP4249983A3 (en) * 2019-02-12 2023-12-06 University of Washington Apparatuses, systems and methods for microscope sample holders
US20220299420A1 (en) * 2019-08-30 2022-09-22 The Regents Of The University Of California Systems and methods for image cytometry
CN114787684A (en) * 2019-11-13 2022-07-22 华盛顿大学 Open top light sheet microscope with non-orthogonal arrangement of illumination and collection objectives
JP7364533B2 (en) 2020-05-26 2023-10-18 株式会社エビデント Observation container and sample preparation method
US20240003835A1 (en) 2020-10-06 2024-01-04 Charité-Universitätsmedizin Berlin Sample Holder Assembly for Optical Microscopy
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WO2022157300A1 (en) 2021-01-22 2022-07-28 Viventis Microscopy Sàrl Microscope for imaging a sample
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Also Published As

Publication number Publication date
JP6445531B2 (en) 2018-12-26
EP3605183A1 (en) 2020-02-05
JP2019066861A (en) 2019-04-25
JP6777715B2 (en) 2020-10-28
US20200233197A1 (en) 2020-07-23
SG11201600146SA (en) 2016-02-26
CN105190399B (en) 2019-04-23
US20180196247A1 (en) 2018-07-12
EP2801855A1 (en) 2014-11-12
US9946057B2 (en) 2018-04-17
EP2801855B1 (en) 2019-07-17
CN110161668B (en) 2021-09-03
US10656404B2 (en) 2020-05-19
US20160070091A1 (en) 2016-03-10
HK1218671A1 (en) 2017-03-03
CN110161668A (en) 2019-08-23
CN105190399A (en) 2015-12-23
JP2016517971A (en) 2016-06-20
WO2014180884A1 (en) 2014-11-13
US20220276479A1 (en) 2022-09-01

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