SG10201809283WA - Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites - Google Patents
Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sitesInfo
- Publication number
- SG10201809283WA SG10201809283WA SG10201809283WA SG10201809283WA SG10201809283WA SG 10201809283W A SG10201809283W A SG 10201809283WA SG 10201809283W A SG10201809283W A SG 10201809283WA SG 10201809283W A SG10201809283W A SG 10201809283WA SG 10201809283W A SG10201809283W A SG 10201809283WA
- Authority
- SG
- Singapore
- Prior art keywords
- bioactivity
- site
- systems
- target sites
- selectively increase
- Prior art date
Links
- 150000002989 phenols Chemical class 0.000 title abstract 5
- 239000003642 reactive oxygen metabolite Substances 0.000 abstract 2
- 206010017943 Gastrointestinal conditions Diseases 0.000 abstract 1
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 206010000059 abdominal discomfort Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 230000001147 anti-toxic effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000004584 weight gain Effects 0.000 abstract 1
- 235000019786 weight gain Nutrition 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
SITE-ACTIVATED BINDING SYSTEMS THAT SELECTIVELY INCREASE THE BIOACTIVITY OF PHENOLIC COMPOUNDS AT TARGET SITES The teachings provided herein generally relate to site-activated binding 5 systems that selectively increase the bioactivity of phenolic compounds at target sites. The systems can include a phenolic compound bound to a reactive oxygen species, wherein the phenolic compound and the reactive oxygen species can react at a target area in the presence of an oxidoreductase enzyme. The systems can be used, for example, as an antitoxin, an anti-inflammatory, or an antimicrobial. 10 Uses can include treatment of a gastrointestinal condition, a damaged dermal tissue, or a damaged mucosal tissue, as well as in promoting gastrointestinal health that can, for example, result in alleviating gastrointestinal discomfort or, perhaps, creating a weight gain in an animal. 15 Figure 6A
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/135,124 US8722040B2 (en) | 2011-06-24 | 2011-06-24 | Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201809283WA true SG10201809283WA (en) | 2018-11-29 |
Family
ID=47362044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201809283WA SG10201809283WA (en) | 2011-06-24 | 2012-06-22 | Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites |
Country Status (17)
Country | Link |
---|---|
US (6) | US8722040B2 (en) |
EP (2) | EP2723334A4 (en) |
JP (3) | JP2014523883A (en) |
KR (1) | KR20140061368A (en) |
CN (2) | CN107126440A (en) |
AU (2) | AU2012272661B2 (en) |
BR (1) | BR112013033125A8 (en) |
CA (1) | CA2840376A1 (en) |
CO (1) | CO6862156A2 (en) |
HK (2) | HK1197177A1 (en) |
MX (1) | MX2013015439A (en) |
MY (1) | MY189659A (en) |
PH (1) | PH12018501201A1 (en) |
RU (1) | RU2014101570A (en) |
SG (1) | SG10201809283WA (en) |
WO (1) | WO2012178127A2 (en) |
ZA (1) | ZA201400532B (en) |
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