SG10201805690RA - Leak-free stopper for a syringe assembly having low breakloose and sustaining forces - Google Patents

Leak-free stopper for a syringe assembly having low breakloose and sustaining forces

Info

Publication number
SG10201805690RA
SG10201805690RA SG10201805690RA SG10201805690RA SG10201805690RA SG 10201805690R A SG10201805690R A SG 10201805690RA SG 10201805690R A SG10201805690R A SG 10201805690RA SG 10201805690R A SG10201805690R A SG 10201805690RA SG 10201805690R A SG10201805690R A SG 10201805690RA
Authority
SG
Singapore
Prior art keywords
stopper
syringe assembly
thermoplastic elastomer
leak
present disclosure
Prior art date
Application number
SG10201805690RA
Inventor
Shishir Prasad
Gheorghe Cojocariu
Sathya Kaliyamoorthy
Chad Smith
Ankur Kulshrestha
Richard Giddes
Gerald Bonczynski
Kweku Addae-Mensah
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Publication of SG10201805690RA publication Critical patent/SG10201805690RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/20—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
    • C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L27/12—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing fluorine atoms
    • C08L27/18—Homopolymers or copolymers or tetrafluoroethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L53/02—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers of vinyl-aromatic monomers and conjugated dienes
    • C08L53/025—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers of vinyl-aromatic monomers and conjugated dienes modified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3101—Leak prevention means for proximal end of syringes, i.e. syringe end opposite to needle mounting end
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Oil, Petroleum & Natural Gas (AREA)

Abstract

LEAK-FREE STOPPER FOR A SYRINGE ASSEMBLY HAVING LOW BREAKLOOSE AND SUSTAINING FORCES A thermoplastic elastomer stopper that meets the desired material properties of a stopper for a syringe assembly is disclosed. The compression set of the thermoplastic elastomer stopper of the present disclosure is <50% when measured at 25% compression for 22 hrs at 70 degree C. The hardness of the thermoplastic elastomer stopper of the present disclosure is 40-70 Shore A. The viscosity of a thermoplastic elastomer stopper of the present disclosure is >70 Pa.s at 1,000 s -1 shear rate, >12.0 Pa.s at 10,000 s -1 shear rate, and >3.0 Pa.s at 50,000 s -1 shear rate when measured using a capillary rheometer at 205 degree C (Die: Roundhole 20 mm length / 1 mm diameter / 180 degree inlet, Piston: d = 15 mm, and melting time = 7 min). The present non-lubricated stopper exhibits the required functional performance of a lubricated stopper. No suitable fig.
SG10201805690RA 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces SG10201805690RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361896332P 2013-10-28 2013-10-28

Publications (1)

Publication Number Publication Date
SG10201805690RA true SG10201805690RA (en) 2018-08-30

Family

ID=51897455

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10202002098XA SG10202002098XA (en) 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces
SG10201805690RA SG10201805690RA (en) 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces
SG11201603308VA SG11201603308VA (en) 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202002098XA SG10202002098XA (en) 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201603308VA SG11201603308VA (en) 2013-10-28 2014-10-28 Leak-free stopper for a syringe assembly having low breakloose and sustaining forces

Country Status (10)

Country Link
US (3) US10493209B2 (en)
EP (2) EP3799906A1 (en)
JP (5) JP6442499B2 (en)
CN (4) CN105813672B (en)
AU (4) AU2014342598B2 (en)
CA (4) CA3191711A1 (en)
ES (1) ES2856216T3 (en)
MX (2) MX2016005432A (en)
SG (3) SG10202002098XA (en)
WO (1) WO2015065942A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3191711A1 (en) 2013-10-28 2015-05-07 Becton, Dickinson And Company Leak-free stopper having low breakloose and sustaining forces
JP2016163642A (en) * 2015-03-06 2016-09-08 大成化工株式会社 Barrel with needle and syringe having the same
US20200164152A1 (en) * 2016-03-13 2020-05-28 Injecto A/S An injector with reduced break loose force
DK3222311T3 (en) * 2016-03-21 2019-11-04 Ba Evolution Gmbh UNLOADED POWER / CYLINDERS SYSTEMS WITH LOW OPERATING POWER AND REDUCED STICK / SLIP
TWI737742B (en) 2016-06-22 2021-09-01 德商梅茲製藥有限兩合公司 Botulinum toxin prefilled syringe system, kit having the same and use thereof
US11124644B2 (en) * 2016-09-01 2021-09-21 University Of Florida Research Foundation, Inc. Organic microgel system for 3D printing of silicone structures
KR20230167451A (en) 2017-01-05 2023-12-08 라이프 테크놀로지스 코포레이션 Coupling Assembly
JP6986843B2 (en) * 2017-02-14 2021-12-22 東海興業株式会社 Resin molded products for sealing
KR102284858B1 (en) 2018-02-23 2021-07-30 주식회사 엘지에너지솔루션 Method of measuring phase stability of slurry of anode mixture
CA3092690A1 (en) * 2018-03-20 2019-09-26 Becton, Dickinson And Company Syringe stopper and plunger rod arrangement for a syringe assembly
CN112041010B (en) * 2018-03-27 2022-11-04 因杰科托集团公司 Low force stopper for use in a syringe
EP3708137A1 (en) * 2019-03-15 2020-09-16 SCHOTT Schweiz AG Pharmaceutical container and liquid composition
US11067473B2 (en) * 2019-06-07 2021-07-20 Packaging Technologies & Inspection, LLC System and method for high voltage leak detection
KR20220163363A (en) * 2020-02-13 2022-12-09 웨스트 파마수티컬 서비시즈, 인코포레이티드 Containment and delivery systems for cryogenic storage
US11933401B2 (en) * 2020-10-09 2024-03-19 Enplas Corporation Plunger, instrument, and mold
EP4171820A4 (en) * 2021-04-16 2024-10-23 Apc Packaging Llc Dropper
US11148131B1 (en) * 2021-04-16 2021-10-19 APC Packaging, LLC. Dropper
EP4426398A1 (en) * 2021-11-03 2024-09-11 Merit Medical Systems, Inc. Living hinge seal for silicone-free syringe barrel
US20230390495A1 (en) * 2022-06-06 2023-12-07 Thome Intellectual Property Holdings, LLC Nested Molded Piston Parts For Multi-Chamber Syringes

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US879611A (en) * 1907-11-22 1908-02-18 Leon Ebner Safety-razor.
US4080357A (en) 1976-06-07 1978-03-21 Shell Oil Company Multicomponent halogenated thermoplastic-block copolymer-polymer blends
US4215701A (en) * 1978-08-21 1980-08-05 Concord Laboratories, Inc. Elastomeric plunger tip for a syringe
JPS62139668A (en) * 1985-12-16 1987-06-23 株式会社大協精工 Laminated plug for syringe
JPH0747045B2 (en) * 1986-10-15 1995-05-24 株式会社大協精工 Stacked syringe stopper
US5211629A (en) * 1991-12-23 1993-05-18 Pressly William B S Safety syringe
US5540410A (en) * 1994-06-10 1996-07-30 Johnson & Johnson Vision Prod Mold halves and molding assembly for making contact lenses
US5632733A (en) 1995-05-11 1997-05-27 Shaw; Thomas J. Tamperproof retractable syringe
EP0757077A1 (en) 1995-08-01 1997-02-05 Advanced Elastomer Systems, L.P. Very soft thermoplastic elastomer compositions
US6066686A (en) 1996-07-05 2000-05-23 Daicel Chemical Industries, Ltd. Polycarbonate compositions
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
JP3648254B2 (en) 1996-11-12 2005-05-18 メドラッド インコーポレーテッド Prefillable syringes and plungers and injectors used with them
JP3387775B2 (en) 1997-05-22 2003-03-17 株式会社大協精工 Sealing stopper for syringe and prefilled syringe
US5985962A (en) * 1997-12-05 1999-11-16 Becton, Dickinson And Company Composition and article of improved compression set
JP3301747B2 (en) 1999-02-12 2002-07-15 ベクトン・ディキンソン・アンド・カンパニー Medical articles with improved adhesive sliding properties
US6599268B1 (en) 2000-06-27 2003-07-29 Becton Dickinson And Company Hypodermic syringe with a selectively retractable needle
JP2002089717A (en) * 2000-09-14 2002-03-27 Terumo Corp Gasket
US7056971B2 (en) 2001-02-13 2006-06-06 Gls Corporation Essentially gas-impermeable thermoplastic elastomer
JP4046988B2 (en) * 2001-11-28 2008-02-13 テルモ株式会社 Syringe gasket, syringe using the same, and method for manufacturing syringe gasket
ES2672623T3 (en) 2004-01-09 2018-06-15 Becton, Dickinson And Company Rinse syringe with positive displacement
JP4473094B2 (en) * 2004-02-20 2010-06-02 リケンテクノス株式会社 Thermoplastic elastomer composition and thermoplastic resin composition using the same
HU226450B1 (en) * 2004-09-20 2008-12-29 Attila Dr Balogh Telerecorder or medical tools movable stock receiver mainly for brain-surgery
US7786216B2 (en) * 2005-03-17 2010-08-31 Dow Global Technologies Inc. Oil based blends of interpolymers of ethylene/α-olefins
US20070000092A1 (en) * 2005-04-27 2007-01-04 Kurt Geffe Rivet hinges and panel flanges
US7909194B2 (en) * 2005-07-01 2011-03-22 Exxonmobil Chemical Patents Inc. Thermoplastic vulcanizates and sealing devices made therewith
CN101282754B (en) * 2005-09-07 2013-04-03 科维蒂恩股份公司 Syringe construction
US7812093B2 (en) 2005-12-19 2010-10-12 Exxonmobil Chemical Patents Inc. Peroxide-cured thermoplastic vulcanizates and medical devices made therewith
KR101059428B1 (en) * 2006-02-17 2011-08-25 에누오케 가부시키가이샤 Hydrogenated NVR Composition
US7943242B2 (en) 2006-03-30 2011-05-17 Becton, Dickinson And Company Sealing members, articles using the same and methods of reducing sticktion
US8075995B2 (en) 2006-03-30 2011-12-13 Becton, Dickinson And Company Coating system, articles and assembly using the same and methods of reducing sticktion
FR2900344B1 (en) * 2006-04-26 2009-02-27 Becton Dickinson France INJECTION DEVICE WITH RETRACTABLE NEEDLE
EP2061529B1 (en) * 2006-09-15 2013-07-24 Becton, Dickinson & Company Medical components having coated surfaces exhibiting low friction and methods of reducing sticktion
ES2866105T3 (en) * 2007-06-04 2021-10-19 Becton Dickinson Co Positive displacement cap for prefilled syringe
JP5185018B2 (en) * 2007-10-05 2013-04-17 住友ゴム工業株式会社 Thermoplastic elastomer composition
US8404976B2 (en) * 2009-01-30 2013-03-26 Fort Wayne Metals Research Products Corporation Fused wires
GB2469055B (en) 2009-03-31 2013-01-02 Dyson Technology Ltd A cleaning appliance with spherical floor engaging arrangement
JP5431051B2 (en) * 2009-07-17 2014-03-05 株式会社大協精工 A small-capacity piston for a syringe and a plunger to which the piston is attached
US8530536B2 (en) * 2009-10-01 2013-09-10 Momentive Performance Materials Inc. Self-lubricating pharmaceutical syringe stoppers
AU2010319826B2 (en) 2009-10-29 2014-07-24 W. L. Gore & Associates, Inc. Syringe stopper coated with expanded PTFE
CN102821804B (en) * 2010-03-30 2015-06-10 泰尔茂株式会社 Medical device with slideable coating, and syringe
JP2011254891A (en) * 2010-06-07 2011-12-22 Coki Engineering Inc Gasket for syringe and pre-filled syringe using the same
CN108744165B (en) * 2011-03-28 2021-02-19 贝克顿·迪金森公司 Plastic stopper
PL2768551T3 (en) * 2011-10-19 2018-01-31 Medtron Ag Syringe for a high pressure injector
WO2013064590A1 (en) * 2011-11-02 2013-05-10 Sanofi-Aventis Deutschland Gmbh Piston for a cartridge for use in a drug delivery device
JP5922404B2 (en) * 2011-12-28 2016-05-24 住友ゴム工業株式会社 Laminated gasket
CA3191711A1 (en) 2013-10-28 2015-05-07 Becton, Dickinson And Company Leak-free stopper having low breakloose and sustaining forces
JP6422706B2 (en) * 2014-08-29 2018-11-14 サトーホールディングス株式会社 Elastic roller

Also Published As

Publication number Publication date
CA2927783C (en) 2018-07-10
CN109224205B (en) 2022-03-04
AU2017203284B2 (en) 2019-05-23
WO2015065942A1 (en) 2015-05-07
MX2021006910A (en) 2021-07-07
EP3062847B1 (en) 2020-12-16
JP7201766B2 (en) 2023-01-10
CA3191711A1 (en) 2015-05-07
JP2016534810A (en) 2016-11-10
MX2016005432A (en) 2016-07-12
EP3799906A1 (en) 2021-04-07
AU2014342598A1 (en) 2016-05-26
AU2017203284A1 (en) 2017-06-08
US20220401654A1 (en) 2022-12-22
CN117258077A (en) 2023-12-22
AU2014342598B2 (en) 2017-02-16
CN109224205A (en) 2019-01-18
AU2020210178A1 (en) 2020-08-13
JP6442499B2 (en) 2018-12-19
JP2022002738A (en) 2022-01-11
CA3098761A1 (en) 2015-05-07
CA2927783A1 (en) 2015-05-07
EP3062847A1 (en) 2016-09-07
CN114522301A (en) 2022-05-24
US20200129703A1 (en) 2020-04-30
ES2856216T3 (en) 2021-09-27
AU2019219839B2 (en) 2020-05-07
CN105813672A (en) 2016-07-27
AU2019219839A1 (en) 2019-09-12
CA3006194C (en) 2020-12-29
JP2019055229A (en) 2019-04-11
JP7012799B2 (en) 2022-01-28
CN105813672B (en) 2023-10-27
US20150119817A1 (en) 2015-04-30
CN114522301B (en) 2024-07-19
US10493209B2 (en) 2019-12-03
SG11201603308VA (en) 2016-05-30
JP2023030108A (en) 2023-03-07
US11471605B2 (en) 2022-10-18
SG10202002098XA (en) 2020-04-29
AU2020210178B2 (en) 2021-08-05
CA3006194A1 (en) 2015-05-07
JP2021003600A (en) 2021-01-14
JP7004633B2 (en) 2022-01-21
CA3098761C (en) 2023-04-18

Similar Documents

Publication Publication Date Title
SG10201805690RA (en) Leak-free stopper for a syringe assembly having low breakloose and sustaining forces
MX2017000368A (en) Hydrogel compositions.
MX2016017093A (en) Microfluidic delivery system for releasing fluid compositions.
EP3448971A4 (en) Random copolymers of acrylates as polymeric friction modifiers, and lubricants containing same
BR112015019846A2 (en) elastic fixation adhesive and its use
EP3590574A3 (en) Cartridge portion of transdermal drug delivery apparatus and methods
MX2016002482A (en) Scalp care composition.
IL291320A (en) Syringe systems, piston seal systems, stopper systems, and methods of use and assembly
AR100088A1 (en) TREATMENT FLUID
CA2885848C (en) Non-irritating lubricant compositions with active sensorial agents
SA518391465B1 (en) Synthetic Polymer Based Fluid Loss Pill
GB2463582A (en) Functional fluid compositions
NZ725569A (en) Lubricant formulations
WO2014190295A3 (en) Two part assembly
BR112017001396A2 (en) self-lubricating polymer composition
MX2014002038A (en) A piston rod foot.
BR112016005793A2 (en) COMPOSITION OF VULCANIZABLE RUBBER, PROCESS FOR MANUFACTURING A VULCANISED ARTICLE, AND VULCANISED ARTICLE
EP3078718A3 (en) Core-shell particles, compositions incorporating the core-shell particles and methods of making the same
PH12016501256A1 (en) Injectable agent and depot formation method
WO2014151358A3 (en) Anaerobic curable compositions
MX2015012068A (en) Lubricating oil composition.
EP3575289A4 (en) Alkanolamine, friction-reducing agent, and lubricating oil composition
MX2017002473A (en) Hot-melt adhesive agent.
BR112015031795A2 (en) mesh comprising a fastening material
BR112017024984A2 (en) propylene copolymer composition, and article