SG10201805672UA - Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms - Google Patents

Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms

Info

Publication number
SG10201805672UA
SG10201805672UA SG10201805672UA SG10201805672UA SG10201805672UA SG 10201805672U A SG10201805672U A SG 10201805672UA SG 10201805672U A SG10201805672U A SG 10201805672UA SG 10201805672U A SG10201805672U A SG 10201805672UA SG 10201805672U A SG10201805672U A SG 10201805672UA
Authority
SG
Singapore
Prior art keywords
amino acids
methods
compositions
hydrogenotrophic microorganisms
biological production
Prior art date
Application number
SG10201805672UA
Inventor
Jill Bradshaw
Zhihao Hu
Jay Kouba
Original Assignee
Trelys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trelys Inc filed Critical Trelys Inc
Publication of SG10201805672UA publication Critical patent/SG10201805672UA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01003—Homoserine dehydrogenase (1.1.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01039—Homoserine kinase (2.7.1.39)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004—Aspartate kinase (2.7.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/03—Amine-lyases (4.3.3)
    • C12Y403/03007—4-Hydroxy-tetrahydrodipicolinate synthase (4.3.3.7)

Abstract

COMPOSITIONSAND METHODS FOR BIOLOGICAL PRODUCTION OF AMINO ACIDS IN HYDROGENOTROPHIC MICROORGANISMS The present disclosure provides compositions and methods for using hydrogenotrophic microorganisms capable of biologically utilizing or converting H and CO and/or CO 2 gas into high-value molecules and biological material, such as essential amino acids (e.g., lysine, threonine, methionine) and animal feed. (Fig. 1) 101
SG10201805672UA 2014-01-02 2015-01-02 Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms SG10201805672UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461923120P 2014-01-02 2014-01-02

Publications (1)

Publication Number Publication Date
SG10201805672UA true SG10201805672UA (en) 2018-08-30

Family

ID=52424116

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201605423UA SG11201605423UA (en) 2014-01-02 2015-01-02 Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms
SG10201805672UA SG10201805672UA (en) 2014-01-02 2015-01-02 Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201605423UA SG11201605423UA (en) 2014-01-02 2015-01-02 Compositions and methods for biological production of amino acids in hydrogenotrophic microorganisms

Country Status (10)

Country Link
US (2) US20170130211A1 (en)
EP (1) EP3090070B1 (en)
JP (1) JP2017500896A (en)
KR (1) KR20160106109A (en)
CN (1) CN106062176A (en)
AU (1) AU2015204088A1 (en)
BR (1) BR112016015573A2 (en)
CA (1) CA2935698A1 (en)
SG (2) SG11201605423UA (en)
WO (1) WO2015103497A1 (en)

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SG11201708741YA (en) 2015-05-06 2017-11-29 Trelys Inc Compositions and methods for biological production of methionine
AT517476B1 (en) * 2015-10-29 2017-02-15 Technische Universität Wien Cell culture status determination
TW202247855A (en) 2016-09-13 2022-12-16 美商愛力根公司 Non-protein clostridial toxin compositions
EP3570682A4 (en) * 2017-01-17 2021-03-03 White Dog Labs, Inc. Proteinic biomass preparation comprising a non-native organism of the clostridia class
US11439172B2 (en) * 2017-07-03 2022-09-13 Oakbio, Inc. Microbial biomass based feed products
US11535830B2 (en) 2017-07-11 2022-12-27 Adisseo France S.A.S. Threonine-producing yeast
EP3704224A4 (en) * 2017-10-31 2021-09-08 INVISTA Textiles (U.K.) Limited Nutritive compositions and methods related thereto
KR102079741B1 (en) * 2018-10-02 2020-02-20 이화여자대학교 산학협력단 A formate removing composition comprising Methanobacterium congolense and a method for producing a succinate using the same
WO2020252335A1 (en) * 2019-06-14 2020-12-17 Trelys, Inc. Processes and systems for producing products by fermentation
CN111019878B (en) * 2020-01-13 2021-04-16 江南大学 Recombinant escherichia coli with improved L-threonine yield as well as construction method and application thereof
CN111394286A (en) * 2020-04-29 2020-07-10 北京大学第三医院（北京大学第三临床医学院） Method for culturing helicobacter pylori in vitro
US11112174B1 (en) * 2020-08-26 2021-09-07 Next Carbon Solutions, Llc Devices, systems, facilities, and processes for liquefied natural gas production
CN113201514B (en) * 2020-10-16 2022-09-06 中国科学院天津工业生物技术研究所 Polypeptides having aspartokinase activity and their use for producing amino acids
CN113337429B (en) * 2021-06-03 2023-11-14 四川发展中恒能环境科技有限公司 Microbial agent for treating kitchen waste organic waste and application thereof
EP4144846A1 (en) * 2021-09-04 2023-03-08 350 PPM Biotech GmbH Carbon dioxide-consuming expression system
CN116622596A (en) * 2022-02-10 2023-08-22 廊坊梅花生物技术开发有限公司 Modified corynebacterium microorganism, construction method thereof and application thereof in threonine production
EP4296369A1 (en) 2022-06-24 2023-12-27 Arkeon GmbH Method for producing amino acids in a bioreactor
EP4296367A1 (en) 2022-06-24 2023-12-27 Arkeon GmbH Method for fermentatively producing norvaline
EP4296368A1 (en) 2022-06-24 2023-12-27 Arkeon GmbH Method for producing amino acids with methanogenic microorganisms in a bioreactor
EP4296354A1 (en) 2022-06-24 2023-12-27 Arkeon GmbH Method for producing amino acids in a bioreactor with methanogenic microorganisms

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JPH06277081A (en) * 1992-11-19 1994-10-04 Shimizu Corp Production of 5-aminolevulinic acid by methane-producing bacterium
GB9518220D0 (en) 1995-09-06 1995-11-08 Medical Res Council Checkpoint gene
US6299774B1 (en) * 2000-06-26 2001-10-09 Jack L. Ainsworth Anaerobic digester system
US20110111413A1 (en) 2001-02-02 2011-05-12 Padgett Hal S Method of optimizing codon usage through dna shuffling
DE102004035074A1 (en) * 2004-07-20 2006-02-16 Basf Ag P1-34 expression units
JP2007068437A (en) * 2005-09-05 2007-03-22 Chisso Corp Variant aspartokinase and method for utilizing the same
KR100905381B1 (en) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Microorganism producing l-methionine precursor and method of producing l-methionine and organic acid from the l-methionine precurosr
EP2628792A1 (en) * 2012-02-17 2013-08-21 Evonik Industries AG Cell with reduced ppGppase activity

Also Published As

Publication number Publication date
BR112016015573A2 (en) 2017-10-03
JP2017500896A (en) 2017-01-12
EP3090070A1 (en) 2016-11-09
US20190194630A1 (en) 2019-06-27
AU2015204088A1 (en) 2016-07-21
US20170130211A1 (en) 2017-05-11
SG11201605423UA (en) 2016-07-28
EP3090070B1 (en) 2020-04-29
WO2015103497A1 (en) 2015-07-09
CN106062176A (en) 2016-10-26
CA2935698A1 (en) 2015-07-09
KR20160106109A (en) 2016-09-09

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