SG10201708103RA - Novel α4β7 Peptide Dimer Antagonists - Google Patents
Novel α4β7 Peptide Dimer AntagonistsInfo
- Publication number
- SG10201708103RA SG10201708103RA SG10201708103RA SG10201708103RA SG10201708103RA SG 10201708103R A SG10201708103R A SG 10201708103RA SG 10201708103R A SG10201708103R A SG 10201708103RA SG 10201708103R A SG10201708103R A SG 10201708103RA SG 10201708103R A SG10201708103R A SG 10201708103RA
- Authority
- SG
- Singapore
- Prior art keywords
- novel
- peptide dimer
- antagonists
- dimer antagonists
- peptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361807714P | 2013-04-02 | 2013-04-02 | |
US14/229,784 US20140294901A1 (en) | 2013-04-02 | 2014-03-28 | Novel a4b7 peptide dimer antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201708103RA true SG10201708103RA (en) | 2017-11-29 |
Family
ID=51621089
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201708103RA SG10201708103RA (en) | 2013-04-02 | 2014-03-31 | Novel α4β7 Peptide Dimer Antagonists |
SG11201508178UA SG11201508178UA (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE DIMER ANTAGONISTS |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201508178UA SG11201508178UA (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE DIMER ANTAGONISTS |
Country Status (10)
Country | Link |
---|---|
US (2) | US20140294901A1 (fr) |
EP (1) | EP2981544B1 (fr) |
JP (1) | JP6499157B2 (fr) |
KR (1) | KR20160011625A (fr) |
CN (1) | CN105339383A (fr) |
AU (2) | AU2014248321A1 (fr) |
CA (1) | CA2908593A1 (fr) |
HK (1) | HK1221233A1 (fr) |
SG (2) | SG10201708103RA (fr) |
WO (1) | WO2014165448A1 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
EP2968443B1 (fr) | 2013-03-15 | 2021-09-29 | Protagonist Therapeutics, Inc. | Analogues d'hepcidine et leurs utilisations |
LT3143037T (lt) | 2014-05-16 | 2021-10-11 | Protagonist Therapeutics, Inc. | Alfa4beta7 integrino tioeterio peptidų antagonistaii |
CN113563423A (zh) | 2014-07-17 | 2021-10-29 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
EP3201217A4 (fr) | 2014-10-01 | 2018-07-18 | Protagonist Therapeutics Inc. | Nouveaux peptides monomères et dimères cycliques possédant une activité antagoniste de l'intégrine |
US9809623B2 (en) | 2014-10-01 | 2017-11-07 | Protagonist Therapeutics, Inc. | α4β7 peptide monomer and dimer antagonists |
US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
AU2016340763B2 (en) * | 2015-10-23 | 2021-04-22 | Jai Prakash | Integrin binding peptides and uses thereof |
WO2017117411A1 (fr) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues de mimétiques d'hepcidine à demi-vie in vivo améliorée |
CN109195618A (zh) * | 2016-03-23 | 2019-01-11 | 领导医疗有限公司 | 用于合成α4β7肽拮抗剂的方法 |
US10278957B2 (en) | 2017-09-11 | 2019-05-07 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
CA3089868A1 (fr) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Mimetiques d'hepcidine conjugues |
MX2022000397A (es) | 2019-07-10 | 2022-04-25 | Protagonist Therapeutics Inc | Inhibidores peptídicos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. |
WO2021146454A1 (fr) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Inhibiteurs peptidiques du récepteur de l'interleukine-23 et leur utilisation pour traiter des maladies inflammatoires |
CR20220332A (es) | 2020-01-15 | 2022-11-28 | Janssen Biotech Inc | Inhibidores de péptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias |
PE20240631A1 (es) | 2020-11-20 | 2024-03-26 | Janssen Pharmaceutica Nv | Composiciones de inhibidores peptidicos del receptor de interleucina-23 |
CN114874107B (zh) * | 2022-07-12 | 2022-11-29 | 中山大学附属第七医院(深圳) | 一种氨基脂质及其制备方法和应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6037324A (en) * | 1996-01-04 | 2000-03-14 | Leukosite, Inc. | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor |
GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
US6818617B1 (en) * | 1997-08-15 | 2004-11-16 | Temple University- Of The Commonwealth System Of Higher Education | EC-3, an inhibitor of α4β1 and α4β7 integrins |
EP1033983A1 (fr) * | 1997-11-24 | 2000-09-13 | Merck & Co., Inc. | Derives d'acide amine cycliques utilises comme inhibiteurs de l'adhesion cellulaire |
SK9072003A3 (en) * | 2001-01-09 | 2003-11-04 | Merck Patent Gmbh | Combination therapy using receptor tyrosine kinase inhibitors and angiogenesis inhibitors |
GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
US9193790B2 (en) * | 2006-12-07 | 2015-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of antagonists of the interaction between HIV GP120 and A4B7 integrin |
WO2009039185A1 (fr) * | 2007-09-17 | 2009-03-26 | The Trustees Of Columbia University In The City Of New York | Utilisations d'un échafaudage modifié immunologiquement pour la prévascularisation d'un tissu et la transplantation de cellules |
JP2011231085A (ja) * | 2010-04-30 | 2011-11-17 | Osaka Prefecture Univ | 環状ペプチド |
EP2444101A1 (fr) * | 2010-10-21 | 2012-04-25 | Universitätsklinikum Freiburg | Ciblage sélectif de l'interaction CD40L/Mac-1 par des inhibiteurs de petits peptides et son utilisation pour la traitement de l'inflammation et de l'athérogénèse |
US9273093B2 (en) * | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
-
2014
- 2014-03-28 US US14/229,784 patent/US20140294901A1/en not_active Abandoned
- 2014-03-31 SG SG10201708103RA patent/SG10201708103RA/en unknown
- 2014-03-31 KR KR1020157031177A patent/KR20160011625A/ko not_active Application Discontinuation
- 2014-03-31 EP EP14779463.0A patent/EP2981544B1/fr active Active
- 2014-03-31 WO PCT/US2014/032391 patent/WO2014165448A1/fr active Application Filing
- 2014-03-31 SG SG11201508178UA patent/SG11201508178UA/en unknown
- 2014-03-31 CA CA2908593A patent/CA2908593A1/fr not_active Abandoned
- 2014-03-31 CN CN201480028920.2A patent/CN105339383A/zh active Pending
- 2014-03-31 JP JP2016506352A patent/JP6499157B2/ja active Active
- 2014-03-31 AU AU2014248321A patent/AU2014248321A1/en not_active Abandoned
-
2016
- 2016-08-05 HK HK16109329.5A patent/HK1221233A1/zh unknown
-
2017
- 2017-12-08 US US15/836,648 patent/US20190002500A1/en not_active Abandoned
-
2018
- 2018-08-27 AU AU2018220168A patent/AU2018220168A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6499157B2 (ja) | 2019-04-10 |
EP2981544A1 (fr) | 2016-02-10 |
AU2018220168A1 (en) | 2018-09-13 |
CN105339383A (zh) | 2016-02-17 |
US20140294901A1 (en) | 2014-10-02 |
SG11201508178UA (en) | 2015-11-27 |
KR20160011625A (ko) | 2016-02-01 |
CA2908593A1 (fr) | 2014-10-09 |
WO2014165448A1 (fr) | 2014-10-09 |
EP2981544B1 (fr) | 2019-09-04 |
HK1221233A1 (zh) | 2017-05-26 |
EP2981544A4 (fr) | 2016-12-07 |
AU2014248321A1 (en) | 2015-10-29 |
US20190002500A1 (en) | 2019-01-03 |
JP2016518351A (ja) | 2016-06-23 |
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