SG10201705094SA - Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same - Google Patents

Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same

Info

Publication number
SG10201705094SA
SG10201705094SA SG10201705094SA SG10201705094SA SG10201705094SA SG 10201705094S A SG10201705094S A SG 10201705094SA SG 10201705094S A SG10201705094S A SG 10201705094SA SG 10201705094S A SG10201705094S A SG 10201705094SA SG 10201705094S A SG10201705094S A SG 10201705094SA
Authority
SG
Singapore
Prior art keywords
site
methods
same
specific induction
quadruplex
Prior art date
Application number
SG10201705094SA
Inventor
Anh Tuan Phan
Kah Wai Lim
Original Assignee
Univ Nanyang Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nanyang Tech filed Critical Univ Nanyang Tech
Publication of SG10201705094SA publication Critical patent/SG10201705094SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/30—Production chemically synthesised

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201705094SA 2012-12-21 2013-12-20 Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same SG10201705094SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261745009P 2012-12-21 2012-12-21

Publications (1)

Publication Number Publication Date
SG10201705094SA true SG10201705094SA (en) 2017-07-28

Family

ID=50978905

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201705094SA SG10201705094SA (en) 2012-12-21 2013-12-20 Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same
SG11201504691TA SG11201504691TA (en) 2012-12-21 2013-12-20 Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201504691TA SG11201504691TA (en) 2012-12-21 2013-12-20 Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same

Country Status (4)

Country Link
US (1) US10822607B2 (en)
EP (1) EP2935585B1 (en)
SG (2) SG10201705094SA (en)
WO (1) WO2014098773A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11390867B2 (en) * 2016-04-29 2022-07-19 Nanyang Technological University G-quadruplex-containing antisense oligonucleotides
CA2954115C (en) * 2016-10-16 2022-04-12 Neil Gordon Ultra-sensitive bioanalyte quantification from self-assembled quadruplex tags
EP3871679A4 (en) * 2018-10-25 2022-10-12 National University Corporation Kumamoto University Method for suppressing protein translation reaction using staple nucleic acid

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582979A (en) * 1989-04-21 1996-12-10 Marshfield Clinic Length polymorphisms in (dC-dA)n.(dG-dT)n sequences and method of using the same
US5449616A (en) * 1990-05-23 1995-09-12 University Of Iowa Research Foundation Nucleic acid encoding dystrophin-associated protein
US5472841A (en) * 1990-06-11 1995-12-05 Nexstar Pharmaceuticals, Inc. Methods for identifying nucleic acid ligands of human neutrophil elastase
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
US5658738A (en) * 1994-05-31 1997-08-19 Becton Dickinson And Company Bi-directional oligonucleotides that bind thrombin
WO1996011010A1 (en) 1994-10-07 1996-04-18 Pharmagenics, Inc. Bridged and unbridged quadruplex/duplex oligonucleotides
US5948897A (en) * 1996-06-14 1999-09-07 Simon Fraser University Method of binding two or more DNA double helices and products formed
US20030017137A1 (en) * 1998-07-22 2003-01-23 Caroline Alfieri Vpr-driven dna or rna construct and therapeutic uses thereof
WO2000024939A1 (en) * 1998-10-27 2000-05-04 Affymetrix, Inc. Complexity management and analysis of genomic dna
EP1136567A1 (en) * 2000-03-24 2001-09-26 Advanced Array Technologies S.A. Method and kit for the screening, the detection and /or the quantification of transcriptional factors
NO20006130D0 (en) * 2000-12-01 2000-12-01 Erling Sundrehagen Reagent and assay method
US20030068636A1 (en) * 2001-06-21 2003-04-10 Millennium Pharmaceuticals, Inc. Compositions, kits and methods for identification, assessment, prevention, and therapy of breast and ovarian cancer
US7297494B2 (en) * 2001-06-25 2007-11-20 Georgia Tech Research Corporation Activatable probes and methods for in vivo gene detection
WO2011103407A1 (en) * 2010-02-19 2011-08-25 The Ohio State University Primers and methods for nucleic acid amplification

Also Published As

Publication number Publication date
WO2014098773A1 (en) 2014-06-26
SG11201504691TA (en) 2015-07-30
US10822607B2 (en) 2020-11-03
EP2935585B1 (en) 2019-04-10
US20160046932A1 (en) 2016-02-18
EP2935585A1 (en) 2015-10-28
EP2935585A4 (en) 2016-08-24

Similar Documents

Publication Publication Date Title
HK1215284A1 (en) Site-specific enzymes and methods of use
GB2500915B (en) Arrangement and method
EP2838468A4 (en) Intra-oral light-therapy apparatuses and methods for their use
EP2820527A4 (en) Apparatus and associated methods
EP2884984A4 (en) Therapeutic compositions and methods
EP2807015A4 (en) Improved laminating apparatus and method of using the same
EP2828615A4 (en) Lasergrammetry system and methods
GB201216649D0 (en) Agents and methods
EP2914061A4 (en) Induction heating apparatus
EP2919983A4 (en) Articles including frims and methods of using them
GB2500285B (en) improved electrofusion fittings and methods
EP2904881A4 (en) Torches and methods of using them
SG11201408326TA (en) Preparation method for perfluoro-2-methyl-3-pentanone and intermediate
EP2871914A4 (en) Heating device and heating method
PT3506664T (en) Gateway charging method and gateway
EP2837624A4 (en) 4-substituent-2-hydroxylmorpholine-3-one and preparation method thereof
SG11201500474PA (en) Nutriculture member and nutriculture method
SG10201705094SA (en) Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same
HK1176343A1 (en) Modified grapheme and preparation method thereof
GB201213778D0 (en) Process and dressng
GB201220930D0 (en) Induction charger
GB201222820D0 (en) Woolscouring method and composition
GB201206859D0 (en) Method and composition
ZA201500172B (en) Plant-disease-control composition and plant-disease-control method
GB201222736D0 (en) Composition and process