SG10201704745UA - Novel compounds and compositions for targeting cancer stem cells - Google Patents

Novel compounds and compositions for targeting cancer stem cells

Info

Publication number
SG10201704745UA
SG10201704745UA SG10201704745UA SG10201704745UA SG10201704745UA SG 10201704745U A SG10201704745U A SG 10201704745UA SG 10201704745U A SG10201704745U A SG 10201704745UA SG 10201704745U A SG10201704745U A SG 10201704745UA SG 10201704745U A SG10201704745U A SG 10201704745UA
Authority
SG
Singapore
Prior art keywords
compositions
stem cells
novel compounds
cancer stem
targeting cancer
Prior art date
Application number
SG10201704745UA
Inventor
David Leggett
Chiang Jia Li
Youzhi Li
Wei Li
Original Assignee
Boston Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Biomedical Inc filed Critical Boston Biomedical Inc
Publication of SG10201704745UA publication Critical patent/SG10201704745UA/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
SG10201704745UA 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells SG10201704745UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31589010P 2010-03-19 2010-03-19
US31588610P 2010-03-19 2010-03-19
US32581410P 2010-04-19 2010-04-19

Publications (1)

Publication Number Publication Date
SG10201704745UA true SG10201704745UA (en) 2017-07-28

Family

ID=50940329

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201502079VA SG10201502079VA (en) 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells
SG10201704745UA SG10201704745UA (en) 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells
SG10201706265PA SG10201706265PA (en) 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201502079VA SG10201502079VA (en) 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201706265PA SG10201706265PA (en) 2010-03-19 2011-03-21 Novel compounds and compositions for targeting cancer stem cells

Country Status (9)

Country Link
EP (2) EP3295796A1 (en)
JP (11) JP2014098049A (en)
CN (4) CN107311969B (en)
CA (3) CA2959931A1 (en)
DK (1) DK3108750T3 (en)
ES (1) ES2689928T3 (en)
NZ (2) NZ712826A (en)
RU (2) RU2657750C1 (en)
SG (3) SG10201502079VA (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2194987T3 (en) 2007-09-10 2016-08-15 Boston Biomedical Inc Newly known group of stat3 signaling pathway inhibitors and cancer stem cell inhibitors
EP2547205B1 (en) * 2010-03-19 2024-03-20 1Globe Biomedical Co., Ltd. Novel methods for targeting cancer stem cells
CN107311969B (en) * 2010-03-19 2022-01-28 北京强新生物科技有限公司 Novel compounds and compositions for targeting cancer stem cells
KR20150139955A (en) 2013-04-09 2015-12-14 보스톤 바이오메디칼, 인크. 2-acetylnaphtho[2,3-b]furan-4,9-dione for use on treating cancer
EA201792623A1 (en) * 2015-06-03 2018-04-30 Бостон Биомедикал, Инк. COMPOSITIONS CONTAINING CANCER STEM BONE INHIBITOR AND IMMUNOTHERAPEUTIC AGENT TO BE USED IN CANCER TREATMENT
GB201515391D0 (en) * 2015-08-28 2015-10-14 Amazentis Sa Compositions
GB201515387D0 (en) * 2015-08-28 2015-10-14 Amazentis Sa Compositions
JP6751658B2 (en) 2016-11-15 2020-09-09 クラリオン株式会社 Voice recognition device, voice recognition system
CA3045306A1 (en) 2016-11-29 2018-06-07 Boston Biomedical, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
JP2020520923A (en) 2017-05-17 2020-07-16 ボストン バイオメディカル, インコーポレイテッド Methods for treating cancer

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61205257A (en) * 1985-03-08 1986-09-11 Ishihara Sangyo Kaisha Ltd Benzoylurea compound, production thereof, and anticancer drug containing same
EP0945131A1 (en) * 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Peroral drug suspension
JP2003525862A (en) * 1999-01-27 2003-09-02 ザ ユニヴァーシティー オブ サウス フロリダ Inhibition of STAT3 signaling for treatment of human cancer
WO2004026253A2 (en) * 2002-09-17 2004-04-01 Arqule, Inc. Novel lapacho compounds and methods of use thereof
CL2003002353A1 (en) * 2002-11-15 2005-02-04 Vertex Pharma COMPOUNDS DERIVED FROM DIAMINOTRIAZOLS, INHIBITORS D ELA PROTEINA QUINASA; PHARMACEUTICAL COMPOSITION; PREPARATION PROCEDURE; AND ITS USE OF THE COMPOUND IN THE TREATMENT OF DISEASES OF ALLERGIC DISORDERS, PROLIFERATION, AUTOIMMUNES, CONDIC
EP1849830B1 (en) * 2005-01-28 2012-02-29 Takeda Pharmaceutical Company Limited Finely divided composition containing poorly water soluble substance
JP2006290871A (en) * 2005-03-16 2006-10-26 Taheebo Japan Kk Compound exhibiting anti-cancer property, intermediate therefor and method for producing the same
WO2007041479A2 (en) * 2005-09-30 2007-04-12 Smithkline Beecham Corporation Pharmaceutical compositions
EP1860126A1 (en) * 2006-05-26 2007-11-28 INEOS Manufacturing Belgium NV Polyolefin powder
DK2194987T3 (en) 2007-09-10 2016-08-15 Boston Biomedical Inc Newly known group of stat3 signaling pathway inhibitors and cancer stem cell inhibitors
AU2009267683B2 (en) * 2008-07-08 2014-04-03 Beta Pharma, Inc. Icotinib hydrochloride, synthesis, crystallographic form, medical combination, and uses thereof
NZ602328A (en) * 2010-03-19 2014-11-28 Boston Biomedical Inc Novel compounds and compositions for targeting cancer stem cells
CN107311969B (en) * 2010-03-19 2022-01-28 北京强新生物科技有限公司 Novel compounds and compositions for targeting cancer stem cells
EP2547205B1 (en) * 2010-03-19 2024-03-20 1Globe Biomedical Co., Ltd. Novel methods for targeting cancer stem cells

Also Published As

Publication number Publication date
RU2657750C1 (en) 2018-06-15
JP2014098048A (en) 2014-05-29
NZ712826A (en) 2017-03-31
JP2015098489A (en) 2015-05-28
EP3108750A1 (en) 2016-12-28
JP2014098050A (en) 2014-05-29
RU2015142279A (en) 2018-12-28
JP2020063308A (en) 2020-04-23
SG10201502079VA (en) 2015-06-29
JP6246169B2 (en) 2017-12-13
SG10201706265PA (en) 2017-08-30
CA2959951A1 (en) 2011-09-22
JP2018002744A (en) 2018-01-11
ES2689928T3 (en) 2018-11-16
CN104016951B (en) 2016-07-13
CA2959931A1 (en) 2011-09-22
JP5993390B2 (en) 2016-09-14
CN104016951A (en) 2014-09-03
JP2018115209A (en) 2018-07-26
EP3295796A1 (en) 2018-03-21
CN107311969A (en) 2017-11-03
JP2016222723A (en) 2016-12-28
JP2014098049A (en) 2014-05-29
CN106860443A (en) 2017-06-20
CN107311969B (en) 2022-01-28
JP2020114888A (en) 2020-07-30
RU2015142279A3 (en) 2019-02-26
CA2993363A1 (en) 2011-09-22
JP2015232037A (en) 2015-12-24
CN107721958A (en) 2018-02-23
JP2022020002A (en) 2022-01-27
NZ701237A (en) 2016-04-29
EP3108750B1 (en) 2018-07-04
DK3108750T3 (en) 2018-10-22

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