SG10201608088YA - Method and apparatus - Google Patents

Method and apparatus

Info

Publication number
SG10201608088YA
SG10201608088YA SG10201608088YA SG10201608088YA SG10201608088YA SG 10201608088Y A SG10201608088Y A SG 10201608088YA SG 10201608088Y A SG10201608088Y A SG 10201608088YA SG 10201608088Y A SG10201608088Y A SG 10201608088YA SG 10201608088Y A SG10201608088Y A SG 10201608088YA
Authority
SG
Singapore
Application number
SG10201608088YA
Inventor
Matthew Green
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectura Ltd filed Critical Vectura Ltd
Publication of SG10201608088YA publication Critical patent/SG10201608088YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/06Jet mills
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • A61M2207/10Device therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22Mixing of ingredients for pharmaceutical or medical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG10201608088YA 2012-03-30 2013-03-28 Method and apparatus SG10201608088YA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1205632.1A GB201205632D0 (en) 2012-03-30 2012-03-30 Method and apparatus

Publications (1)

Publication Number Publication Date
SG10201608088YA true SG10201608088YA (en) 2016-11-29

Family

ID=46159980

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201405555RA SG11201405555RA (en) 2012-03-30 2013-03-28 Method and apparatus
SG10201608088YA SG10201608088YA (en) 2012-03-30 2013-03-28 Method and apparatus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201405555RA SG11201405555RA (en) 2012-03-30 2013-03-28 Method and apparatus

Country Status (16)

Country Link
US (1) US20150059746A1 (en)
EP (1) EP2830751A1 (en)
JP (1) JP2015516950A (en)
KR (1) KR20140142264A (en)
CN (1) CN104203385A (en)
AU (1) AU2013239409A1 (en)
CA (1) CA2867097A1 (en)
GB (1) GB201205632D0 (en)
HK (1) HK1206670A1 (en)
IL (1) IL234659A0 (en)
IN (1) IN2014DN08753A (en)
MX (1) MX2014011795A (en)
NZ (1) NZ629920A (en)
RU (1) RU2014143807A (en)
SG (2) SG11201405555RA (en)
WO (1) WO2013144655A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107851B2 (en) 2012-10-15 2015-08-18 New Jersey Institute Of Technology Solventless mixing process for coating pharmaceutical ingredients
WO2014078258A1 (en) * 2012-11-16 2014-05-22 Merck Sharp & Dohme Corp. Process for making agglomerates using acoustic mixing technology
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
JP2016518388A (en) 2013-04-30 2016-06-23 オティトピック インク. Dry powder formulation and usage
WO2015049519A2 (en) * 2013-10-02 2015-04-09 Vectura Limited Method and apparatus
GB201321712D0 (en) * 2013-12-09 2014-01-22 Pharmachemie Bv Dry Powder Inhaler
WO2015094927A1 (en) * 2013-12-17 2015-06-25 Merck Sharp & Dohme Corp. Media milling process for the manufacture of active pharmaceutical ingredients in propellants
US20180021256A1 (en) * 2014-07-09 2018-01-25 Arven Ilac Sanayi Ve Ticaret A.S. Process for the preparation of formulations for inhalation
PL3191081T3 (en) 2014-09-09 2020-09-07 Vectura Limited Formulation comprising glycopyrrolate, method and apparatus
WO2016156970A1 (en) 2015-04-01 2016-10-06 Lupin Pharmaceuticals Inc. Process for manufacturing dry powder blends
US9968223B2 (en) 2015-06-12 2018-05-15 Sunbeam Products, Inc. Blending appliance with paddle blade
JPWO2017047650A1 (en) * 2015-09-14 2018-06-28 大和製罐株式会社 Powder inhaler, inhaler, and method for producing powder inhaler
WO2019059953A2 (en) 2017-09-22 2019-03-28 Otitopic Inc. Dry powder compositions with magnesium stearate
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
US11642333B2 (en) * 2019-05-23 2023-05-09 Anovent Pharmaceutical (U.S.), Llc Inhalable formulation of a solution containing vilanterol trifenatate and umeclidinium bromide
CN111297837B (en) * 2020-03-26 2022-02-22 上海方予健康医药科技有限公司 Preparation method of dry powder inhalant
CN113144997B (en) * 2021-03-23 2022-10-25 西安近代化学研究所 Method and system for determining critical fluctuation rate and judging mixing uniformity in resonant sound mixing
US20230182094A1 (en) * 2021-12-14 2023-06-15 Honeywell Federal Manufacturing & Technologies, Llc Resonant acoustic mixing system and method
WO2023196663A1 (en) * 2022-04-07 2023-10-12 Board Of Regents, The University Of Texas System Methods of preparing carrier-based dry powders for inhalation
WO2023235267A2 (en) * 2022-05-28 2023-12-07 Avalyn Pharma Inc. Nintedanib and nintedanib combination dry powder compositions and uses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4990696A (en) * 1995-02-24 1996-09-11 Nanosystems L.L.C. Aerosols containing nanoparticle dispersions
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
JP2004533917A (en) * 2001-05-01 2004-11-11 グラクソ グループ リミテッド Deagglomeration apparatus and method
GB0205327D0 (en) * 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
WO2003090717A1 (en) * 2002-04-23 2003-11-06 Nanotherapeutics, Inc Process of forming and modifying particles and compositions produced thereby
US7188993B1 (en) * 2003-01-27 2007-03-13 Harold W Howe Apparatus and method for resonant-vibratory mixing
WO2005025730A1 (en) * 2003-09-10 2005-03-24 Burr Ronald F Acoustic fluidized bed
GB0321607D0 (en) * 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0605676D0 (en) * 2006-03-22 2006-05-03 Vectura Ltd Improvements in extraction of powder formulations
EP2082767A1 (en) * 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2309978B1 (en) * 2008-06-26 2018-12-26 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
EP3090792A1 (en) * 2008-07-18 2016-11-09 Prosonix Limited Process for improving crystallinity
KR20130062268A (en) * 2010-04-21 2013-06-12 키에시 파르마슈티시 엣스. 피. 에이. Process for providing particles with reduced electrostatic charges
WO2011136363A1 (en) 2010-04-28 2011-11-03 三洋電機株式会社 Method for manufacturing circuit device
RU2666963C2 (en) * 2012-04-13 2018-09-13 Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Aggregated particles
WO2014078258A1 (en) * 2012-11-16 2014-05-22 Merck Sharp & Dohme Corp. Process for making agglomerates using acoustic mixing technology

Also Published As

Publication number Publication date
HK1206670A1 (en) 2016-01-15
WO2013144655A1 (en) 2013-10-03
KR20140142264A (en) 2014-12-11
CA2867097A1 (en) 2013-10-03
SG11201405555RA (en) 2014-11-27
AU2013239409A1 (en) 2014-09-25
MX2014011795A (en) 2015-01-12
IN2014DN08753A (en) 2015-05-22
NZ629920A (en) 2017-03-31
RU2014143807A (en) 2016-05-27
EP2830751A1 (en) 2015-02-04
JP2015516950A (en) 2015-06-18
IL234659A0 (en) 2014-11-30
CN104203385A (en) 2014-12-10
GB201205632D0 (en) 2012-05-16
US20150059746A1 (en) 2015-03-05

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