SG10201602245YA - Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule - Google Patents

Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule

Info

Publication number
SG10201602245YA
SG10201602245YA SG10201602245YA SG10201602245YA SG10201602245YA SG 10201602245Y A SG10201602245Y A SG 10201602245YA SG 10201602245Y A SG10201602245Y A SG 10201602245YA SG 10201602245Y A SG10201602245Y A SG 10201602245YA SG 10201602245Y A SG10201602245Y A SG 10201602245YA
Authority
SG
Singapore
Prior art keywords
detecting
recombinant protein
analyte molecule
protein biosensors
biosensors
Prior art date
Application number
SG10201602245YA
Inventor
Saurabh Rajendra Nirantar
Farid John Ghadessy
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG10201602245YA priority Critical patent/SG10201602245YA/en
Publication of SG10201602245YA publication Critical patent/SG10201602245YA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG10201602245YA 2011-03-23 2012-03-22 Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule SG10201602245YA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG10201602245YA SG10201602245YA (en) 2011-03-23 2012-03-22 Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG2011020872 2011-03-23
SG10201602245YA SG10201602245YA (en) 2011-03-23 2012-03-22 Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule

Publications (1)

Publication Number Publication Date
SG10201602245YA true SG10201602245YA (en) 2016-05-30

Family

ID=46879946

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602245YA SG10201602245YA (en) 2011-03-23 2012-03-22 Recombinant Protein Biosensors And A Method For Detecting The Presence Of An Analyte Molecule
SG2013070396A SG193534A1 (en) 2011-03-23 2012-03-22 Recombinant protein biosensors and a method for detecting the presence of an analyte molecule

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013070396A SG193534A1 (en) 2011-03-23 2012-03-22 Recombinant protein biosensors and a method for detecting the presence of an analyte molecule

Country Status (4)

Country Link
US (1) US20140178895A1 (en)
EP (1) EP2688912B1 (en)
SG (2) SG10201602245YA (en)
WO (1) WO2012128722A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024102823A2 (en) * 2022-11-09 2024-05-16 The Regents Of The University Of California Systems and methods for detecting and/or screening protein aggregation and/or disaggregation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8669074B2 (en) * 1996-01-31 2014-03-11 The Regents Of The University Of California Chimeric phosphorylation indicator
CA2336985C (en) * 1998-07-17 2011-01-04 University Of Maryland, Baltimore Method of glucose or galactose detection with glucose/galactose binding protein
JP3650815B2 (en) * 2000-11-22 2005-05-25 大学共同利用機関法人自然科学研究機構 Method for producing biosensor protein capable of controlling fluorescence characteristics of green fluorescent protein, and biosensor protein produced by the method
GB0111459D0 (en) * 2001-05-10 2001-07-04 Isis Innovation Universal fluorescent sensors
WO2003068945A2 (en) * 2002-02-14 2003-08-21 Kalobios, Inc. Detection of molecular interaction by reactivation of an auto-inhibited responder (rair)
US20070264678A1 (en) * 2005-10-28 2007-11-15 Invitrogen Corporation Kinase and ubiquination assays
WO2008109161A2 (en) * 2007-03-07 2008-09-12 The Albert Einstein College Of Medicine Of Yeshiva University Deeply quenched enzyme sensors
WO2009079618A1 (en) * 2007-12-18 2009-06-25 Cytodesign, Inc. Enzyme engineering systems and methods
US8940506B2 (en) * 2008-03-21 2015-01-27 The Regents Of The University Of California High-sensitive fluorescent energy transfer assay using fluoresent amino acids and fluorescent proteins
AU2010208181B2 (en) * 2009-01-30 2015-04-30 Presympto, Inc. Conformationally dynamic peptides

Also Published As

Publication number Publication date
WO2012128722A2 (en) 2012-09-27
EP2688912B1 (en) 2016-11-09
EP2688912A2 (en) 2014-01-29
WO2012128722A3 (en) 2012-10-18
US20140178895A1 (en) 2014-06-26
SG193534A1 (en) 2013-10-30
EP2688912A4 (en) 2014-09-17

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