SG10201602176RA - Intranasal benzodiazepine pharmaceutical compositions - Google Patents

Intranasal benzodiazepine pharmaceutical compositions

Info

Publication number
SG10201602176RA
SG10201602176RA SG10201602176RA SG10201602176RA SG10201602176RA SG 10201602176R A SG10201602176R A SG 10201602176RA SG 10201602176R A SG10201602176R A SG 10201602176RA SG 10201602176R A SG10201602176R A SG 10201602176RA SG 10201602176R A SG10201602176R A SG 10201602176RA
Authority
SG
Singapore
Prior art keywords
pharmaceutical compositions
intranasal
intranasal benzodiazepine
benzodiazepine pharmaceutical
benzodiazepine
Prior art date
Application number
SG10201602176RA
Inventor
Gary Bream
Moise A Khayrallah
Myoung-Ki Baek
Jae-Hoon Jo
Hye-Jin Chang
Original Assignee
Acorda Therapeutics Inc
Sk Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics Inc, Sk Biopharmaceuticals Co Ltd filed Critical Acorda Therapeutics Inc
Publication of SG10201602176RA publication Critical patent/SG10201602176RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
SG10201602176RA 2011-03-31 2012-03-30 Intranasal benzodiazepine pharmaceutical compositions SG10201602176RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161469940P 2011-03-31 2011-03-31

Publications (1)

Publication Number Publication Date
SG10201602176RA true SG10201602176RA (en) 2016-04-28

Family

ID=46928023

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201602176RA SG10201602176RA (en) 2011-03-31 2012-03-30 Intranasal benzodiazepine pharmaceutical compositions
SG2013072319A SG193958A1 (en) 2011-03-31 2012-03-30 Intranasal benzodiazepine pharmaceutical compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013072319A SG193958A1 (en) 2011-03-31 2012-03-30 Intranasal benzodiazepine pharmaceutical compositions

Country Status (16)

Country Link
US (3) US20120252793A1 (en)
EP (1) EP2691100A4 (en)
JP (1) JP2014509655A (en)
KR (1) KR20140029426A (en)
CN (1) CN103619338B (en)
AR (1) AR085927A1 (en)
AU (1) AU2012236334B2 (en)
BR (1) BR112013024968A2 (en)
CA (1) CA2831308A1 (en)
HK (1) HK1195252A1 (en)
MX (1) MX357800B (en)
PH (1) PH12017501688A1 (en)
RU (2) RU2013148120A (en)
SG (2) SG10201602176RA (en)
TW (1) TWI601532B (en)
WO (1) WO2012135619A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101517415B1 (en) 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 Transnasal anticonvulsive pharmaceutical composition comprising poorly soluble anticonvulsant
JP5929800B2 (en) * 2012-04-03 2016-06-08 コニカミノルタ株式会社 Fixing solution and image forming method
CA3064840A1 (en) * 2017-06-02 2018-12-06 Xeris Pharmaceuticals, Inc. Precipitation resistant small molecule drug formulations
US11129818B2 (en) 2017-06-07 2021-09-28 Arcutis Biotherapeutics, Inc. Topical roflumilast formulation having improved delivery and plasma half life
US9895359B1 (en) 2017-06-07 2018-02-20 Arcutis, Inc. Inhibition of crystal growth of roflumilast
US11534493B2 (en) * 2017-09-22 2022-12-27 Arcutis Biotherapeutics, Inc. Pharmaceutical compositions of roflumilast in aqueous blends of water-miscible, pharmaceutically acceptable solvents
CN111836615A (en) 2018-01-05 2020-10-27 英倍尔药业股份有限公司 Intranasal delivery of olanzapine by precision nasal device
WO2019182745A1 (en) * 2018-03-19 2019-09-26 Bryn Pharma, LLC Epinephrine spray formulations
CN111529489A (en) * 2020-04-17 2020-08-14 山东省药学科学院 Nasal spray containing diazepam

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4990797A (en) * 1996-10-24 1998-05-15 Alza Corporation Permeation enhancers for transdermal drug delivery compositions, devices, and methods
KR100715513B1 (en) * 1999-07-26 2007-05-08 에스케이 코오포레이션 Transnasal anticonvulsive compositions
AU2002333785A1 (en) * 2002-09-03 2004-03-29 Pharmacure Health Care Ab Nasal sprays
TW200824693A (en) * 2006-08-28 2008-06-16 Jazz Pharmaceuticals Inc Pharmaceutical compositions of clonazepam and methods of use thereof
US7745430B2 (en) * 2006-11-15 2010-06-29 Sk Holdings Co., Ltd. Transnasal anticonvulsive pharmaceutical composition
CN101842079B (en) * 2007-08-31 2012-09-05 阿基米德开发有限公司 Non-aqueous pharmaceutical compositions
KR101517415B1 (en) * 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 Transnasal anticonvulsive pharmaceutical composition comprising poorly soluble anticonvulsant
JP2013505248A (en) * 2009-09-16 2013-02-14 アラーガン インコーポレイテッド Compositions and methods for treating seizure disorders

Also Published As

Publication number Publication date
AU2012236334A1 (en) 2013-10-10
MX357800B (en) 2018-07-25
US20140128381A1 (en) 2014-05-08
MX2013011336A (en) 2013-12-16
EP2691100A4 (en) 2014-09-24
US20120252793A1 (en) 2012-10-04
CN103619338B (en) 2016-06-22
WO2012135619A2 (en) 2012-10-04
SG193958A1 (en) 2013-11-29
TW201302204A (en) 2013-01-16
PH12017501688A1 (en) 2018-09-10
TWI601532B (en) 2017-10-11
AU2012236334B2 (en) 2017-02-16
JP2014509655A (en) 2014-04-21
AR085927A1 (en) 2013-11-06
EP2691100A2 (en) 2014-02-05
WO2012135619A3 (en) 2012-11-22
CN103619338A (en) 2014-03-05
RU2018135967A (en) 2018-11-14
KR20140029426A (en) 2014-03-10
BR112013024968A2 (en) 2016-12-20
HK1195252A1 (en) 2014-11-07
CA2831308A1 (en) 2012-10-04
US20170151258A1 (en) 2017-06-01
RU2013148120A (en) 2015-05-10

Similar Documents

Publication Publication Date Title
AP3864A (en) Pharmaceutical composition
GB201113662D0 (en) Pharmaceutical compositions
ZA201308208B (en) Pharmaceutical compositions
HK1199824A1 (en) Pharmaceutical compositions
GB201118232D0 (en) Pharmaceutical composition
HK1195252A1 (en) Intranasal benzodiazepine pharmaceutical compositions
HK1189158A1 (en) Pharmaceutical composition
EP2763756A4 (en) Bromofluorocarbon compositions
GB201118181D0 (en) Pharmaceutical compositions
GB201110833D0 (en) Compositions
EP2727593A4 (en) Nicorandil-containing pharmaceutical composition
GB201103942D0 (en) Compositions
EP2711010A4 (en) Pharmaceutical composition
HUP1100444A2 (en) Pharmaceutical composition
GB201110132D0 (en) compositions
GB201104849D0 (en) Compositions
EP2714715A4 (en) Pharmaceutical compositions
HUP1100445A2 (en) Pharmaceutical composition
GB201105224D0 (en) Novel pharmaceutical compositions
GB201117165D0 (en) Compositions
GB201114629D0 (en) Compositions
GB201109121D0 (en) Compositions
GB201108338D0 (en) Compositions
GB201107998D0 (en) Compositions
GB201108040D0 (en) Compositions