SG10201509919UA - Treatment of jak2-mediated conditions - Google Patents
Treatment of jak2-mediated conditionsInfo
- Publication number
- SG10201509919UA SG10201509919UA SG10201509919UA SG10201509919UA SG10201509919UA SG 10201509919U A SG10201509919U A SG 10201509919UA SG 10201509919U A SG10201509919U A SG 10201509919UA SG 10201509919U A SG10201509919U A SG 10201509919UA SG 10201509919U A SG10201509919U A SG 10201509919UA
- Authority
- SG
- Singapore
- Prior art keywords
- jak2
- treatment
- mediated conditions
- mediated
- conditions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41947610P | 2010-12-03 | 2010-12-03 | |
| US201161492485P | 2011-06-02 | 2011-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201509919UA true SG10201509919UA (en) | 2016-01-28 |
Family
ID=46171087
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201509919UA SG10201509919UA (en) | 2010-12-03 | 2011-11-29 | Treatment of jak2-mediated conditions |
| SG2013042239A SG190950A1 (en) | 2010-12-03 | 2011-11-29 | Treatment of jak2-mediated conditions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013042239A SG190950A1 (en) | 2010-12-03 | 2011-11-29 | Treatment of jak2-mediated conditions |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140073643A1 (en) |
| EP (1) | EP2646029A4 (en) |
| JP (2) | JP2013544260A (en) |
| KR (1) | KR20130137011A (en) |
| CN (2) | CN103370068A (en) |
| AU (1) | AU2011335882B2 (en) |
| BR (1) | BR112013013684A2 (en) |
| CA (1) | CA2819560A1 (en) |
| EA (1) | EA201390815A1 (en) |
| MX (1) | MX2013006261A (en) |
| NZ (1) | NZ611654A (en) |
| SG (2) | SG10201509919UA (en) |
| WO (1) | WO2012071612A1 (en) |
| ZA (1) | ZA201304280B (en) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2348023B9 (en) | 2005-12-13 | 2017-03-08 | Incyte Holdings Corporation | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors |
| KR20150043565A (en) | 2007-03-12 | 2015-04-22 | 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 | Phenyl amino pyrimidine compounds and uses thereof |
| CN101932582B (en) | 2007-06-13 | 2013-09-25 | 因塞特公司 | Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| SG176111A1 (en) | 2009-05-22 | 2011-12-29 | Incyte Corp | 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors |
| ME02386B (en) | 2010-03-10 | 2016-09-20 | Incyte Holdings Corp | Piperidin-4-yl azetidine derivatives as jak1 inhibitors |
| KR102303885B1 (en) | 2010-05-21 | 2021-09-24 | 인사이트 홀딩스 코포레이션 | Topical formulation for a jak inhibitor |
| EP2640723A1 (en) | 2010-11-19 | 2013-09-25 | Incyte Corporation | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors |
| US8691807B2 (en) | 2011-06-20 | 2014-04-08 | Incyte Corporation | Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors |
| UA111854C2 (en) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | METHODS AND INTERMEDIATE COMPOUNDS FOR JAK INHIBITORS |
| US8809359B2 (en) | 2012-06-29 | 2014-08-19 | Ym Biosciences Australia Pty Ltd | Phenyl amino pyrimidine bicyclic compounds and uses thereof |
| EP2877596A1 (en) * | 2012-07-27 | 2015-06-03 | Novartis AG | Prediction of treatment response to jak/stat inhibitor |
| EA201590930A1 (en) | 2012-11-15 | 2015-08-31 | Инсайт Корпорейшн | DOSAGE FORMS OF RUXOLITINIB WITH Slow Release. |
| CN103965114B (en) * | 2013-01-28 | 2016-01-06 | 苏州泽璟生物制药有限公司 | Deuterated phenyl amino pyrimidine compounds and comprise the pharmaceutical composition of this compound |
| JP6397831B2 (en) | 2013-03-06 | 2018-09-26 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Method for producing JAK inhibitor and intermediate thereof |
| WO2014161046A1 (en) * | 2013-04-04 | 2014-10-09 | The Walter And Eliza Hall Institute Of Medical Research | Methods of treating diseases characterized by excessive wnt signalling |
| MY195091A (en) | 2013-08-07 | 2023-01-10 | Incyte Corp | Sustained Release Dosage Forms for a JAK1 Inhibitor |
| SI3110409T1 (en) * | 2014-02-28 | 2018-11-30 | Incyte Corporation | Jak1 inhibitors for the treatment of myelodysplastic syndromes |
| WO2015184305A1 (en) | 2014-05-30 | 2015-12-03 | Incyte Corporation | TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1 |
| TWI681954B (en) | 2014-06-12 | 2020-01-11 | 美商西爾拉癌症醫學公司 | N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide |
| AR101504A1 (en) | 2014-08-11 | 2016-12-21 | Acerta Pharma Bv | THERAPEUTIC COMBINATIONS OF A BTK INHIBITOR, A PI3K INHIBITOR, A JAK-2 INHIBITOR, AND / OR A CDK4 / 6 INHIBITOR |
| HRP20220738T1 (en) | 2014-08-11 | 2022-08-19 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor, a pi3k inhibitor, a jak-2 inhibitor, a pd-1 inhibitor and/or a pd-l1 inhibitor |
| EP3179991B1 (en) | 2014-08-11 | 2021-10-06 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor and a bcl-2 inhibitor |
| CN106316964B (en) * | 2015-06-26 | 2019-06-25 | 苏州泽璟生物制药股份有限公司 | The polymorph of phenyl amino pyrimidine compounds or its salt |
| CN106316963B (en) * | 2015-06-26 | 2021-06-08 | 苏州泽璟生物制药股份有限公司 | Polymorphs of a morpholino phenylaminopyrimidine compound or salt thereof |
| WO2018031579A1 (en) | 2016-08-10 | 2018-02-15 | Gilead Sciences, Inc. | Momelotinib for treating of acvr1 -mediated diseases |
| WO2019113487A1 (en) | 2017-12-08 | 2019-06-13 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| CR20200379A (en) | 2018-01-30 | 2021-03-05 | Incyte Corp | Processes for preparing (1 -(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one) |
| CN109045040A (en) * | 2018-03-12 | 2018-12-21 | 首都医科大学附属北京天坛医院 | CYT387 is used to prepare the application of the drug for the treatment of glioma |
| CA3095487A1 (en) | 2018-03-30 | 2019-10-03 | Incyte Corporation | Treatment of hidradenitis suppurativa using jak inhibitors |
| KR20210047308A (en) * | 2018-08-21 | 2021-04-29 | 시에라 온코로지, 인코퍼레이티드 | Platelet count-unspecified method to treat myelofibrosis |
| JP2022517951A (en) * | 2019-01-10 | 2022-03-11 | スミトモ ダイニッポン ファーマ オンコロジー， インコーポレイテッド | ALK5 inhibitor for treating myelodysplastic syndrome |
| CA3166545A1 (en) * | 2020-01-29 | 2021-08-05 | Igor THEURL | Methods of using momelotinib to treat joint inflammation |
| CN111358791A (en) * | 2020-03-13 | 2020-07-03 | 深圳百奥捷生物科技有限公司 | Application of JAK/STAT signal pathway phosphate inhibitor in preparation of medicine for treating DBA diseases |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150043565A (en) * | 2007-03-12 | 2015-04-22 | 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 | Phenyl amino pyrimidine compounds and uses thereof |
| WO2009073575A2 (en) * | 2007-11-30 | 2009-06-11 | Oregon Health & Science University | Methods for treating induced cellular proliferative disorders |
| KR20110053347A (en) * | 2008-08-05 | 2011-05-20 | 탈자진 인코포레이티드 | Methods of treating thalassemia |
-
2011
- 2011-11-29 CA CA2819560A patent/CA2819560A1/en not_active Abandoned
- 2011-11-29 US US13/991,139 patent/US20140073643A1/en not_active Abandoned
- 2011-11-29 CN CN2011800639895A patent/CN103370068A/en active Pending
- 2011-11-29 SG SG10201509919UA patent/SG10201509919UA/en unknown
- 2011-11-29 MX MX2013006261A patent/MX2013006261A/en not_active Application Discontinuation
- 2011-11-29 WO PCT/AU2011/001551 patent/WO2012071612A1/en active Application Filing
- 2011-11-29 JP JP2013541149A patent/JP2013544260A/en active Pending
- 2011-11-29 KR KR1020137017256A patent/KR20130137011A/en not_active Application Discontinuation
- 2011-11-29 AU AU2011335882A patent/AU2011335882B2/en active Active
- 2011-11-29 BR BR112013013684A patent/BR112013013684A2/en not_active IP Right Cessation
- 2011-11-29 EP EP11845391.9A patent/EP2646029A4/en not_active Withdrawn
- 2011-11-29 NZ NZ611654A patent/NZ611654A/en unknown
- 2011-11-29 CN CN201410578333.2A patent/CN104473933A/en active Pending
- 2011-11-29 EA EA201390815A patent/EA201390815A1/en unknown
- 2011-11-29 SG SG2013042239A patent/SG190950A1/en unknown
-
2013
- 2013-06-11 ZA ZA2013/04280A patent/ZA201304280B/en unknown
-
2015
- 2015-08-13 JP JP2015159834A patent/JP2015212305A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011335882A1 (en) | 2013-05-02 |
| EP2646029A4 (en) | 2014-06-18 |
| SG190950A1 (en) | 2013-07-31 |
| WO2012071612A1 (en) | 2012-06-07 |
| JP2015212305A (en) | 2015-11-26 |
| ZA201304280B (en) | 2014-08-27 |
| MX2013006261A (en) | 2013-10-01 |
| NZ611654A (en) | 2015-08-28 |
| JP2013544260A (en) | 2013-12-12 |
| CN103370068A (en) | 2013-10-23 |
| CN104473933A (en) | 2015-04-01 |
| EA201390815A1 (en) | 2013-12-30 |
| EP2646029A1 (en) | 2013-10-09 |
| AU2011335882B2 (en) | 2016-03-10 |
| KR20130137011A (en) | 2013-12-13 |
| US20140073643A1 (en) | 2014-03-13 |
| CA2819560A1 (en) | 2012-06-07 |
| BR112013013684A2 (en) | 2016-09-06 |
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