SG10201503717PA - Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates - Google Patents

Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates

Info

Publication number
SG10201503717PA
SG10201503717PA SG10201503717PA SG10201503717PA SG10201503717PA SG 10201503717P A SG10201503717P A SG 10201503717PA SG 10201503717P A SG10201503717P A SG 10201503717PA SG 10201503717P A SG10201503717P A SG 10201503717PA SG 10201503717P A SG10201503717P A SG 10201503717PA
Authority
SG
Singapore
Prior art keywords
picolinates
fluoro
chloro
amino
substituted
Prior art date
Application number
SG10201503717PA
Inventor
Yuanming Zhu
Gregory T Whiteker
Kim E Arndt
James M Renga
Robert D Froese
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of SG10201503717PA publication Critical patent/SG10201503717PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C07D213/807—Processes of preparation by oxidation of pyridines or condensed pyridines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG10201503717PA 2011-01-25 2012-01-24 Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates SG10201503717PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161435974P 2011-01-25 2011-01-25

Publications (1)

Publication Number Publication Date
SG10201503717PA true SG10201503717PA (en) 2015-06-29

Family

ID=46544649

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013056049A SG192579A1 (en) 2011-01-25 2012-01-24 Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates
SG10201503717PA SG10201503717PA (en) 2011-01-25 2012-01-24 Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013056049A SG192579A1 (en) 2011-01-25 2012-01-24 Process for the preparation of 4-amino-3-chloro-5-fluoro-6-(substituted)picolinates

Country Status (20)

Country Link
US (2) US8609853B2 (en)
EP (2) EP2667713B1 (en)
JP (1) JP5739019B2 (en)
KR (2) KR101542340B1 (en)
CN (1) CN103429082B (en)
AR (1) AR085023A1 (en)
AU (1) AU2012209280B2 (en)
BR (2) BR102012001638A8 (en)
CA (1) CA2825389C (en)
CO (1) CO6731128A2 (en)
HK (2) HK1187493A1 (en)
IL (1) IL227645B (en)
MX (1) MX339636B (en)
PL (2) PL2667713T3 (en)
RU (1) RU2539578C1 (en)
SG (2) SG192579A1 (en)
TW (2) TWI547482B (en)
UA (1) UA105610C2 (en)
WO (1) WO2012103044A1 (en)
ZA (1) ZA201305579B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609651A (en) 2013-11-12 2016-03-16 陶氏農業科學公司 Process for fluorinating compounds
TW201609652A (en) 2013-11-12 2016-03-16 陶氏農業科學公司 Process for fluorinating compounds
BR102014028164A2 (en) * 2013-11-12 2015-09-08 Dow Agrosciences Llc process for fluorination of compounds
TWI726900B (en) 2015-08-04 2021-05-11 美商陶氏農業科學公司 Process for fluorinating compounds
AU2017209455A1 (en) * 2016-01-22 2018-08-02 Dow Agrosciences Llc Process for the preparation of 4-alkoxy-3-acetoxypicolinic acids
CN109415319A (en) * 2016-05-19 2019-03-01 美国陶氏益农公司 Synthesizing aryl carboxylate is coupled by direct Su Chuji
US11401242B2 (en) 2018-09-19 2022-08-02 Corteva Agriscience Llc Preparation of halogen analogs of picloram
CN115298167A (en) 2020-03-18 2022-11-04 科迪华农业科技有限责任公司 Improved synthesis of 6-aryl-4-aminopicolinates
BR112022018508A2 (en) 2020-03-18 2022-10-25 Corteva Agriscience Llc IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803159A (en) * 1967-12-26 1974-04-09 Dow Chemical Co Fluorine containing cyanopyridines
US3629424A (en) * 1967-12-26 1971-12-21 Dow Chemical Co Cyanofluoropyridines and fungicidal compositions and methods for using the same
US3755338A (en) * 1970-12-17 1973-08-28 Dow Chemical Co 4-amino-6-bromo-3,5-dichloropicolinic acid compounds
US3971799A (en) * 1974-12-27 1976-07-27 The Dow Chemical Company Preparation of 3,5,6-trichloropicolinic acid
US4087431A (en) * 1976-05-17 1978-05-02 The Dow Chemical Company Preparation of 3,6-dichloropicolinic acid
US4814456A (en) * 1986-02-10 1989-03-21 The Dow Chemical Company Chlorinating waste streams to recover cyanopyridine contained therein
US4999432A (en) * 1989-08-28 1991-03-12 Dowelanco Fluorination with hydrogen fluoride
US5807804A (en) * 1996-02-22 1998-09-15 American Cyanamid Company Substituted pyridine herbicidal agents
JP3731982B2 (en) * 1997-08-26 2006-01-05 株式会社日本触媒 Method for producing organic fluorine compound
US6297197B1 (en) 2000-01-14 2001-10-02 Dow Agrosciences Llc 4-aminopicolinates and their use as herbicides
KR100560326B1 (en) * 2000-01-14 2006-03-14 다우 아그로사이언시즈 엘엘씨 4-Aminopicolinates and herbicidal compositions comprising the same
AR037228A1 (en) * 2001-07-30 2004-11-03 Dow Agrosciences Llc ACID COMPOUNDS 6- (ARIL OR HETEROARIL) -4-AMYNOPYCOLINIC, HERBICIDE COMPOSITION THAT UNDERSTANDS AND METHOD TO CONTROL UNWANTED VEGETATION
UA82358C2 (en) * 2003-04-02 2008-04-10 Дау Агросайенсиз Ллс 6-alkyl or alkenyl-4-amionopicolinates, herbicidal composition, method for controlling undesirable vegetation
UA81177C2 (en) * 2003-08-04 2007-12-10 Дау Агросайєнсіз Ллс 6-(1,1-difluoroalkyl)-4-aminopicolinates and their use as herbicides
WO2006062979A1 (en) * 2004-12-06 2006-06-15 E.I. Dupont De Nemours And Company Herbicidal 6-cyclopropyl-substitute 4-aminopicolinic acid derivatives
JP5059779B2 (en) 2006-01-13 2012-10-31 ダウ アグロサイエンシィズ エルエルシー 6- (Polysubstituted aryl) -4-aminopicolinates and their use as herbicides
EP2121703A4 (en) * 2006-08-18 2011-12-28 Astrazeneca Ab Thienopyrimidin-4-one and thienopyridazin-7-one derivatives as mch rl antagonists
AR068710A1 (en) * 2007-10-02 2009-12-02 Dow Agrosciences Llc ACIDS 2-SUBSTITUTE-6-AMINO-5-RENT, ALQUENYL OR ALQUINYL-4-PYRIMIDINACARBOXILICO AND PICOLINIC ACIDS 6-SUBSTITUTED -4-AMINO-3-RENT ALQUENILO OR ALQUINILO AND ITS USE AS HERBICIDES
AU2009314948A1 (en) * 2008-11-17 2010-05-20 Ishihara Sangyo Kaisha, Ltd. Pyridine derivative or its salt, pesticide containing it and process for its production
US8252938B2 (en) * 2009-06-08 2012-08-28 Dow Agrosciences, Llc. Process for the preparation of 6-(aryl)-4-aminopicolinates
GB0910766D0 (en) * 2009-06-22 2009-08-05 Syngenta Ltd Chemical compounds
DE102009054573A1 (en) 2009-11-13 2011-05-19 Tracoe Medical Gmbh Tracheostomy tube with window
UA103272C2 (en) * 2009-12-11 2013-09-25 Ф. Хоффманн-Ля Рош Аг 2-amino-5,5-difluoro-5,6-dihydro-4h-[1,3]oxazines as bace1 and/or bace2 inhibitors

Also Published As

Publication number Publication date
US20120190858A1 (en) 2012-07-26
KR20130121951A (en) 2013-11-06
HK1187493A1 (en) 2014-04-11
CN103429082B (en) 2015-05-06
IL227645A0 (en) 2013-09-30
US9598368B2 (en) 2017-03-21
MX2013008604A (en) 2013-08-12
JP5739019B2 (en) 2015-06-24
AU2012209280B2 (en) 2015-08-20
CA2825389A1 (en) 2012-08-02
BR102012001638A2 (en) 2015-07-28
HK1206938A1 (en) 2016-01-22
TWI547482B (en) 2016-09-01
KR101517313B1 (en) 2015-05-04
JP2014511364A (en) 2014-05-15
TWI520943B (en) 2016-02-11
MX339636B (en) 2016-06-01
TW201600511A (en) 2016-01-01
PL2667713T3 (en) 2017-08-31
IL227645B (en) 2018-01-31
CO6731128A2 (en) 2013-08-15
AU2012209280A1 (en) 2013-08-15
ZA201305579B (en) 2014-09-25
US20140046070A1 (en) 2014-02-13
AR085023A1 (en) 2013-08-07
UA105610C2 (en) 2014-05-26
PL2901857T3 (en) 2017-08-31
US8609853B2 (en) 2013-12-17
CA2825389C (en) 2015-12-22
KR101542340B1 (en) 2015-08-05
EP2901857A1 (en) 2015-08-05
BR112013018942A2 (en) 2018-05-22
CN103429082A (en) 2013-12-04
TW201307290A (en) 2013-02-16
EP2667713A1 (en) 2013-12-04
EP2667713A4 (en) 2014-09-10
KR20150006073A (en) 2015-01-15
BR112013018942A8 (en) 2018-07-31
EP2667713B1 (en) 2016-05-04
SG192579A1 (en) 2013-09-30
WO2012103044A1 (en) 2012-08-02
BR102012001638A8 (en) 2018-07-31
RU2539578C1 (en) 2015-01-20
EP2901857B1 (en) 2017-03-01

Similar Documents

Publication Publication Date Title
IL227648B (en) Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted) picolinates
HK1199245A1 (en) Process for the preparation of 4-amino-3-chloro-5-fluoro-6- (substituted) picolinates 4--3--5--6-()-2-
HK1188684A1 (en) Process for the preparation of 4-amino-5-fluoro-3-halo-6- (substituted)picolinates 4--5--3--6-()-2-
ZA201305972B (en) Method for the preparation of biphephos
HK1210613A1 (en) Process for the preparation of 4-amino-5-fluoro-3-halo-6- (substituted)picolinates 4--5--3--6-()-2-
HK1187493A1 (en) Process for the preparation of 4-amino-3-chloro-5-fluoro-6- (substituted)picolinates 4--3--5--6-()-2-
SG11201400939YA (en) Process for the preparation of methoxymelonal
ZA201504166B (en) Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates
IL230904A0 (en) Process for the preparation of complexes of68ga
ZA201504165B (en) Process for the preparation of 4-amino-5-fluoro-3-chloro-6-(substituted)picolinates
IL233938A0 (en) Process for the preparation of substituted phenylpropanones
GB201119690D0 (en) Process for the preparation of compounds
PL393916A1 (en) Process for the preparation of carbapenemic compounds
ZA201309732B (en) Process for the preparation of dexlansoprazole
PL394420A1 (en) process for the preparation of dilauroilfluorescein
PL394378A1 (en) Process for the preparation of E-2-amine-4-nitrostillbenes
HK1170240A1 (en) Process for the preparation of 2-substituted-5-(1-alkylthio) alkylpyridines