SG10201406713XA - Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography - Google Patents
Isolation and purification of anti-il-13 antibodies using protein a affinity chromatographyInfo
- Publication number
- SG10201406713XA SG10201406713XA SG10201406713XA SG10201406713XA SG10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- isolation
- purification
- protein
- affinity chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
- A61K39/39525—Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25341109P | 2009-10-20 | 2009-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201406713XA true SG10201406713XA (en) | 2014-11-27 |
Family
ID=43900936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201406713XA SG10201406713XA (en) | 2009-10-20 | 2010-10-20 | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US8491904B2 (en) |
| EP (2) | EP2491055A2 (en) |
| JP (1) | JP5914342B2 (en) |
| KR (2) | KR20170136649A (en) |
| CN (2) | CN104744560A (en) |
| AU (1) | AU2010310748C1 (en) |
| BR (1) | BR112012009289B8 (en) |
| CA (1) | CA2775595A1 (en) |
| CY (1) | CY1123952T1 (en) |
| DK (1) | DK3037104T3 (en) |
| ES (1) | ES2813398T3 (en) |
| HR (1) | HRP20201118T1 (en) |
| HU (1) | HUE053489T2 (en) |
| IL (1) | IL218897A (en) |
| IN (1) | IN2012DN02778A (en) |
| LT (1) | LT3037104T (en) |
| MX (2) | MX341136B (en) |
| NZ (2) | NZ627668A (en) |
| PL (1) | PL3037104T3 (en) |
| PT (1) | PT3037104T (en) |
| RS (1) | RS60577B1 (en) |
| RU (1) | RU2603055C2 (en) |
| SG (1) | SG10201406713XA (en) |
| SI (1) | SI3037104T1 (en) |
| TW (1) | TWI515202B (en) |
| WO (1) | WO2011050071A2 (en) |
| ZA (1) | ZA201202720B (en) |
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| CA2706419A1 (en) * | 2007-11-30 | 2009-06-04 | Glaxo Group Limited | Antigen-binding constructs binding il-13 |
| CN105111309A (en) * | 2008-10-20 | 2015-12-02 | Abbvie公司 | Isolation and purification of antibodies using protein an appinity chromatography |
| CN102257005A (en) | 2008-10-20 | 2011-11-23 | 雅培制药有限公司 | Viral inactivation during purification of antibodies |
| RS60577B1 (en) | 2009-10-20 | 2020-08-31 | Abbvie Inc | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
| KR101871683B1 (en) | 2010-07-30 | 2018-06-27 | 이엠디 밀리포어 코포레이션 | Chromatogrphy media and method |
| US20130344074A1 (en) | 2011-03-16 | 2013-12-26 | Sanofi | Uses of a dual v region antibody-like protein |
| EP2820149A1 (en) * | 2012-02-27 | 2015-01-07 | Biogen Idec MA Inc. | High-throughput method for sialic acid quantitation |
| EP2970378B1 (en) | 2013-03-15 | 2021-05-26 | Biogen MA Inc. | Hydrophobic interaction protein chromatography under no-salt conditions |
| JP2016519145A (en) * | 2013-05-15 | 2016-06-30 | メディミューン リミテッド | Purification of recombinantly produced polypeptides |
| AR096713A1 (en) | 2013-06-25 | 2016-01-27 | Cadila Healthcare Ltd | PURIFICATION PROCESS FOR MONOCLONAL ANTIBODIES |
| US10519194B2 (en) | 2013-07-12 | 2019-12-31 | Merck Patent Gmbh | Removal of fragments from a sample containing a target protein using activated carbon |
| MY176026A (en) | 2013-09-13 | 2020-07-22 | Genentech Inc | Methods and composions comprising purified recombinant polypeptides |
| JP6546178B2 (en) | 2013-09-13 | 2019-07-17 | ジェネンテック， インコーポレイテッド | Compositions and methods for detecting and quantifying host cell proteins and recombinant polypeptide products in cell lines |
| SG11201602061YA (en) | 2013-09-17 | 2016-04-28 | Kaneka Corp | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom |
| CN105017418B (en) * | 2014-03-27 | 2021-02-23 | 上海药明康德新药开发有限公司 | Monoclonal antibody purification process |
| FR3025515B1 (en) * | 2014-09-05 | 2016-09-09 | Lab Francais Du Fractionnement | PROCESS FOR PURIFYING MONOCLONAL ANTIBODY |
| AR102198A1 (en) | 2014-10-09 | 2017-02-08 | Regeneron Pharma | PROCESS TO REDUCE SUBVISIBLE PARTICLES IN A PHARMACEUTICAL FORMULATION |
| WO2016093926A1 (en) | 2014-12-08 | 2016-06-16 | Emd Millipore Corporation | Mixed bed ion exchange adsorber |
| US11098079B2 (en) | 2015-08-13 | 2021-08-24 | Amgen Inc. | Charged depth filtration of antigen-binding proteins |
| KR20180048731A (en) * | 2015-08-20 | 2018-05-10 | 제넨테크, 인크. | Purification of FKPA to produce recombinant polypeptides and uses thereof |
| IL297519B1 (en) * | 2016-04-27 | 2024-02-01 | Abbvie Inc | Methods of treatment of diseases in which il-13 activity is detrimental using anti-il-13 antibodies |
| IL309453A (en) | 2016-08-16 | 2024-02-01 | Regeneron Pharma | Methods for quantitating individual antibodies from a mixture |
| IL289895B (en) | 2016-10-25 | 2022-09-01 | Regeneron Pharma | Methods and systems for chromatography data analysis |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| AR111465A1 (en) * | 2017-04-14 | 2019-07-17 | Cj Healthcare Corp | METHOD FOR PURIFICATION OF ANALOG ANTIBODIES BY THE USE OF CATION EXCHANGE CHROMATOGRAPHY |
| CN111344410B (en) * | 2017-08-17 | 2023-09-15 | 济世易为生物有限公司 | Method for purifying glycosylated proteins from host cell galectins and other contaminants |
| TW202005694A (en) | 2018-07-02 | 2020-02-01 | 美商里珍納龍藥品有限公司 | Systems and methods for preparing a polypeptide from a mixture |
| BR112021001194A2 (en) * | 2018-07-25 | 2021-04-27 | Daiichi Sankyo Company, Limited | methods for producing an antibody-drug conjugate and for producing a pharmaceutical composition |
| CN110818789B (en) * | 2018-08-07 | 2023-02-28 | 三生国健药业（上海）股份有限公司 | Purification method of high-purity cynomolgus monkey interleukin 17A |
| WO2020106750A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| US20220306727A1 (en) * | 2019-06-05 | 2022-09-29 | Seagen Inc. | Methods of Purifying Masked Antibodies |
| BR112022000847A2 (en) * | 2019-08-01 | 2022-05-31 | Regeneron Pharma | Method for viral inactivation |
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| CN115666704A (en) | 2019-12-13 | 2023-01-31 | 比奥拉治疗股份有限公司 | Ingestible device for delivery of therapeutic agents to the gastrointestinal tract |
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-
2010
- 2010-10-20 RS RS20200864A patent/RS60577B1/en unknown
- 2010-10-20 WO PCT/US2010/053388 patent/WO2011050071A2/en active Application Filing
- 2010-10-20 RU RU2012120751/10A patent/RU2603055C2/en active
- 2010-10-20 KR KR1020177034448A patent/KR20170136649A/en not_active Application Discontinuation
- 2010-10-20 EP EP10777144A patent/EP2491055A2/en not_active Withdrawn
- 2010-10-20 DK DK15189425.0T patent/DK3037104T3/en active
- 2010-10-20 HU HUE15189425A patent/HUE053489T2/en unknown
- 2010-10-20 AU AU2010310748A patent/AU2010310748C1/en active Active
- 2010-10-20 BR BR112012009289A patent/BR112012009289B8/en active IP Right Grant
- 2010-10-20 KR KR1020127012851A patent/KR101830596B1/en active IP Right Grant
- 2010-10-20 CN CN201510208066.4A patent/CN104744560A/en active Pending
- 2010-10-20 TW TW099135795A patent/TWI515202B/en active
- 2010-10-20 NZ NZ627668A patent/NZ627668A/en unknown
- 2010-10-20 CN CN201080057917.5A patent/CN102711828B/en active Active
- 2010-10-20 LT LTEP15189425.0T patent/LT3037104T/en unknown
- 2010-10-20 PL PL15189425T patent/PL3037104T3/en unknown
- 2010-10-20 CA CA2775595A patent/CA2775595A1/en not_active Abandoned
- 2010-10-20 ES ES15189425T patent/ES2813398T3/en active Active
- 2010-10-20 MX MX2014006213A patent/MX341136B/en unknown
- 2010-10-20 EP EP15189425.0A patent/EP3037104B1/en active Active
- 2010-10-20 SI SI201032028T patent/SI3037104T1/en unknown
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