SG10201406713XA - Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography - Google Patents
Isolation and purification of anti-il-13 antibodies using protein a affinity chromatographyInfo
- Publication number
- SG10201406713XA SG10201406713XA SG10201406713XA SG10201406713XA SG10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA SG 10201406713X A SG10201406713X A SG 10201406713XA
- Authority
- SG
- Singapore
- Prior art keywords
- antibodies
- isolation
- purification
- protein
- affinity chromatography
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
- A61K39/39525—Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25341109P | 2009-10-20 | 2009-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201406713XA true SG10201406713XA (en) | 2014-11-27 |
Family
ID=43900936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201406713XA SG10201406713XA (en) | 2009-10-20 | 2010-10-20 | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US8491904B2 (en) |
| EP (2) | EP3037104B1 (en) |
| JP (1) | JP5914342B2 (en) |
| KR (2) | KR20170136649A (en) |
| CN (2) | CN102711828B (en) |
| AU (1) | AU2010310748C1 (en) |
| BR (1) | BR112012009289B8 (en) |
| CA (1) | CA2775595A1 (en) |
| CY (1) | CY1123952T1 (en) |
| DK (1) | DK3037104T3 (en) |
| ES (1) | ES2813398T3 (en) |
| HR (1) | HRP20201118T1 (en) |
| HU (1) | HUE053489T2 (en) |
| IL (1) | IL218897A (en) |
| IN (1) | IN2012DN02778A (en) |
| LT (1) | LT3037104T (en) |
| MX (2) | MX2012004711A (en) |
| NZ (2) | NZ599100A (en) |
| PL (1) | PL3037104T3 (en) |
| PT (1) | PT3037104T (en) |
| RS (1) | RS60577B1 (en) |
| RU (1) | RU2603055C2 (en) |
| SG (1) | SG10201406713XA (en) |
| SI (1) | SI3037104T1 (en) |
| TW (1) | TWI515202B (en) |
| WO (1) | WO2011050071A2 (en) |
| ZA (1) | ZA201202720B (en) |
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| TW200944231A (en) * | 2007-11-30 | 2009-11-01 | Glaxo Group Ltd | Antigen-binding constructs |
| AU2009347206C1 (en) * | 2008-10-20 | 2016-12-08 | Abbvie Inc. | Isolation and purification of antibodies using Protein A affinity chromatography |
| SG10201702951RA (en) | 2008-10-20 | 2017-06-29 | Abbvie Inc | Viral inactivation during purification of antibodies |
| LT3037104T (en) | 2009-10-20 | 2020-09-10 | Abbvie Inc. | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
| KR101871683B1 (en) | 2010-07-30 | 2018-06-27 | 이엠디 밀리포어 코포레이션 | Chromatogrphy media and method |
| JP2014510730A (en) | 2011-03-16 | 2014-05-01 | サノフイ | Use of dual V region antibody-like proteins |
| US20150038362A1 (en) * | 2012-02-27 | 2015-02-05 | Biogen Idec Ma Inc. | High-Throughput Method For Sialic Acid Quantitation |
| WO2014145208A1 (en) * | 2013-03-15 | 2014-09-18 | Biogen Idec Ma Inc. | Hydrophobic interaction protein chromatography under no-salt conditions |
| EP3907233A1 (en) * | 2013-05-15 | 2021-11-10 | MedImmune Limited | Purification of recombinantly produced polypeptides |
| TWI596107B (en) | 2013-06-25 | 2017-08-21 | 卡地拉保健有限公司 | Novel purification process for monoclonal antibodies |
| SG11201508835YA (en) | 2013-07-12 | 2015-11-27 | Merck Patent Gmbh | Removal of fragments from a sample containing a target protein using activated carbon |
| ES2915378T3 (en) * | 2013-09-13 | 2022-06-22 | Hoffmann La Roche | Methods for detecting and quantifying a host cell protein in cell lines |
| NZ756750A (en) * | 2013-09-13 | 2022-05-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| KR20160054597A (en) * | 2013-09-17 | 2016-05-16 | 가부시키가이샤 가네카 | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom |
| CN105017418B (en) * | 2014-03-27 | 2021-02-23 | 上海药明康德新药开发有限公司 | Monoclonal antibody purification process |
| FR3025515B1 (en) * | 2014-09-05 | 2016-09-09 | Lab Francais Du Fractionnement | PROCESS FOR PURIFYING MONOCLONAL ANTIBODY |
| TW201628649A (en) | 2014-10-09 | 2016-08-16 | 再生元醫藥公司 | Process for reducing subvisible particles in a pharmaceutical formulation |
| WO2016093926A1 (en) | 2014-12-08 | 2016-06-16 | Emd Millipore Corporation | Mixed bed ion exchange adsorber |
| EP3334747B1 (en) | 2015-08-13 | 2023-09-27 | Amgen Inc. | Charged depth filtration of antigen-binding proteins |
| CA2995385A1 (en) * | 2015-08-20 | 2017-02-23 | Genentech, Inc. | Purification of fkpa and uses thereof for producing recombinant polypeptides |
| CN109562115A (en) | 2016-04-27 | 2019-04-02 | 艾伯维公司 | Using anti-IL-13 Antybody therapy IL-13 activity wherein harmful disease method |
| IL264631B2 (en) | 2016-08-16 | 2024-05-01 | Regeneron Pharma | Methods for quantitating individual antibodies from a mixture |
| SG11201902667UA (en) | 2016-10-25 | 2019-05-30 | Regeneron Pharma | Methods and systems for chromatography data analysis |
| EP4252629A3 (en) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| WO2018190677A2 (en) * | 2017-04-14 | 2018-10-18 | Cj Healthcare Corporation | Method for purifying analogous antibody using cation-exchange chromatography |
| WO2019036626A1 (en) * | 2017-08-17 | 2019-02-21 | Just Biotherapeutics, Inc. | Method of purifying glycosylated protein from host cell galectins and other contaminants |
| SG11202001564QA (en) | 2017-09-19 | 2020-04-29 | Regeneron Pharma | Methods of reducing particle formation and compositions formed thereby |
| US11884698B2 (en) | 2018-07-02 | 2024-01-30 | Regeneron Pharmaceuticals, Inc. | Systems and methods for preparing a polypeptide from a mixture |
| US20210283269A1 (en) * | 2018-07-25 | 2021-09-16 | Daiichi Sankyo Company, Limited | Effective method for manufacturing antibody-drug conjugate |
| CN110818789B (en) * | 2018-08-07 | 2023-02-28 | 三生国健药业（上海）股份有限公司 | Purification method of high-purity cynomolgus monkey interleukin 17A |
| KR20210095165A (en) | 2018-11-19 | 2021-07-30 | 프로제너티, 인크. | Methods and devices for treating diseases with biopharmaceuticals |
| TW202043253A (en) * | 2019-01-28 | 2020-12-01 | 美商安進公司 | A continuous manufacturing process for biologics manufacturing by integration of drug substance and drug product processes |
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| LT3037104T (en) | 2009-10-20 | 2020-09-10 | Abbvie Inc. | Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography |
-
2010
- 2010-10-20 LT LTEP15189425.0T patent/LT3037104T/en unknown
- 2010-10-20 NZ NZ599100A patent/NZ599100A/en unknown
- 2010-10-20 PL PL15189425T patent/PL3037104T3/en unknown
- 2010-10-20 US US12/908,502 patent/US8491904B2/en active Active
- 2010-10-20 CN CN201080057917.5A patent/CN102711828B/en active Active
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