SE9904650L - New Use - Google Patents
New UseInfo
- Publication number
- SE9904650L SE9904650L SE9904650A SE9904650A SE9904650L SE 9904650 L SE9904650 L SE 9904650L SE 9904650 A SE9904650 A SE 9904650A SE 9904650 A SE9904650 A SE 9904650A SE 9904650 L SE9904650 L SE 9904650L
- Authority
- SE
- Sweden
- Prior art keywords
- oxidizing agent
- enzymatic oxidizing
- composition
- bioadhesive
- chemical cross
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 abstract 6
- 239000007800 oxidant agent Substances 0.000 abstract 6
- 239000000227 bioadhesive Substances 0.000 abstract 5
- 238000010382 chemical cross-linking Methods 0.000 abstract 4
- 239000003431 cross linking reagent Substances 0.000 abstract 4
- 235000018102 proteins Nutrition 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 abstract 2
- 229940024606 amino acid Drugs 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000000945 filler Substances 0.000 abstract 2
- -1 nitroprusside ions Chemical class 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical group FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 102000011632 Caseins Human genes 0.000 abstract 1
- 108010076119 Caseins Proteins 0.000 abstract 1
- 229920001661 Chitosan Chemical group 0.000 abstract 1
- 229920001287 Chondroitin sulfate Chemical group 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000016942 Elastin Human genes 0.000 abstract 1
- 108010014258 Elastin Proteins 0.000 abstract 1
- 102000009123 Fibrin Human genes 0.000 abstract 1
- 108010073385 Fibrin Proteins 0.000 abstract 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 abstract 1
- 102000016359 Fibronectins Human genes 0.000 abstract 1
- 108010067306 Fibronectins Proteins 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical group OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 241000237536 Mytilus edulis Species 0.000 abstract 1
- 125000000837 carbohydrate group Chemical group 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 229940045110 chitosan Drugs 0.000 abstract 1
- 229940059329 chondroitin sulfate Drugs 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 229920002549 elastin Polymers 0.000 abstract 1
- 229950003499 fibrin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920002674 hyaluronan Chemical group 0.000 abstract 1
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 abstract 1
- 229940099552 hyaluronan Drugs 0.000 abstract 1
- 235000020638 mussel Nutrition 0.000 abstract 1
- 229960002460 nitroprusside Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J105/00—Adhesives based on polysaccharides or on their derivatives, not provided for in groups C09J101/00 or C09J103/00
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Abstract
Bioadhesive composition (I) comprises a bioadhesive polyphenolic protein comprising 30-3000 amino acids, comprises tandemly linked peptide repeats of 3-15 amino acid residues; (ii) a polymer comprising carbohydrates; (iii) fine filaments; (iv) optionally a non-enzymatic oxidizing agent; and (v) a filler protein. (I) does not contain an enzymatic oxidizing agent or chemical cross-linking agent. Bioadhesive composition comprises: (i) a bioadhesive polyphenolic protein derived from a byssus-forming mussel comprising 30-3000 amino acids consisting tandemly linked peptide repeats of 3-15 amino acid residues, at least 5% and preferably 6-25% are at least 5 % and preferably 6-25 % has 3,4 dihydroxy-L-phenylalanine (DOPA); (ii) a polymer comprising carbohydrate groups such as heparin, chondroitin sulfate, chitosan and hyaluronan; (iii) fine filaments; (iv) optionally a non-enzymatic oxidizing agent such as hydrogen peroxide, nitroprusside ions or periodate ions; and (v) a filler protein, such as collagen, albumin, casein, elastin, fibronectin or fibrin. (I) does not contain an enzymatic oxidizing agent or chemical cross-linking agent. An Independent claim is also included for: (1) a bioadhesive composition (II) with a composition as (I) which does not comprise any enzymatic oxidizing agent or chemical cross-linking agent, for medical use; and (2) a composition (III) comprising (i) and (ii), and does not comprise any enzymatic oxidizing agent or chemical cross-linking agent.
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9904650A SE516266C2 (en) | 1999-12-17 | 1999-12-17 | Bioadhesive composition not containing enzymatic oxidizing agent or chemical cross-linking agent comprises bioadhesive polyphenolic protein, a polymer, fine filaments, optionally a non-enzymatic oxidizing agent, and a filler protein |
PT05104976T PT1589088E (en) | 1999-12-17 | 2000-12-14 | New bioadhesive composition comprising a bioadhesive polyphenolic protein, a polymer comprising carbohydrate groups, pharmaceutically acceptable fine filaments and uses thereof |
ES00987904T ES2262557T3 (en) | 1999-12-17 | 2000-12-14 | BIOADHESIVE COMPOSITION CONTAINING A POLYPHENOLIC PROTEIN. |
DK00987904T DK1265971T3 (en) | 1999-12-17 | 2000-12-14 | Bioadhesive composition comprising a polyphenol protein |
EP00987904A EP1265971B1 (en) | 1999-12-17 | 2000-12-14 | Bioadhesive composition comprising a polyphenolic protein |
PT00987904T PT1265971E (en) | 1999-12-17 | 2000-12-14 | NEW USE OF A BIOADESIVE COMPOSITION UNDERSTANDING A POLYPHENOLIC PROTEIN |
DE60036236T DE60036236T2 (en) | 1999-12-17 | 2000-12-14 | A novel bioadhesive composition comprising a bioadhesive polyphenolic protein, a polymer having carbohydrate groups, pharmaceutically acceptable fine filaments and their use |
DK05104976T DK1589088T3 (en) | 1999-12-17 | 2000-12-14 | New bioadhesive composition comprising a bioadhesive polyphenolic protein, a polymer comprising carbohydrate groups, and pharmaceutically acceptable thin filaments, and uses thereof |
AU24172/01A AU2417201A (en) | 1999-12-17 | 2000-12-14 | New use of a bioadhesive composition comprising a polyphenolic protein |
AT00987904T ATE324417T1 (en) | 1999-12-17 | 2000-12-14 | BIOADHESIVE COMPOSITION CONTAINING POLYPHENOLIC PROTEIN |
AT05104976T ATE371710T1 (en) | 1999-12-17 | 2000-12-14 | NEW BIOADHESIVE COMPOSITION CONTAINING A BIOADHESIVE POLYPHENOLIC PROTEIN, A POLYMER WITH CARBOHYDRATE GROUPS, PHARMACEUTICALLY ACCEPTABLE FINE FILAMENTS AND USE THEREOF |
EP05104976A EP1589088B1 (en) | 1999-12-17 | 2000-12-14 | New bioadhesive composition comprising a bioadhesive polyphenolic protein, a polymer comprising carbohydrate groups, pharmaceutically acceptable fine filaments and uses thereof |
US10/168,093 US6867188B2 (en) | 1999-12-17 | 2000-12-14 | Use of a bioadhesive composition comprising a polyphenolic protein |
PCT/SE2000/002533 WO2001044401A1 (en) | 1999-12-17 | 2000-12-14 | New use of a bioadhesive composition comprising a polyphenolic protein |
DE60027606T DE60027606T2 (en) | 1999-12-17 | 2000-12-14 | POLYPHENOLIC PROTEIN CONTAINING BIOADHESIVE COMPOSITION |
ES05104976T ES2292060T3 (en) | 1999-12-17 | 2000-12-14 | MOVING BIOADHESIVE COMPOSITION INCLUDING A POLYPHENOLIC PROTEIN, A POLYMER THAT INCLUDES CARBOHYDRATE GROUPS, FINE PHARMACEUTICAL ACCEPTANCE FILMS AND ITS USES. |
US11/073,684 US20050148050A1 (en) | 1999-12-17 | 2005-03-08 | Bioadhesive composition comprising a polyphenolic protein |
CY20071101433T CY1106984T1 (en) | 1999-12-17 | 2007-11-08 | A NEW BIOLOGICAL COMPOSITION THAT CONTAINS A BIOLOGICAL POLYPHENOLIC PROTEIN, A POLYMER CONTAINING LIGHT CARBON GROUPS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9904650A SE516266C2 (en) | 1999-12-17 | 1999-12-17 | Bioadhesive composition not containing enzymatic oxidizing agent or chemical cross-linking agent comprises bioadhesive polyphenolic protein, a polymer, fine filaments, optionally a non-enzymatic oxidizing agent, and a filler protein |
Publications (3)
Publication Number | Publication Date |
---|---|
SE9904650D0 SE9904650D0 (en) | 1999-12-17 |
SE9904650L true SE9904650L (en) | 2001-06-18 |
SE516266C2 SE516266C2 (en) | 2001-12-10 |
Family
ID=20418186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9904650A SE516266C2 (en) | 1999-12-17 | 1999-12-17 | Bioadhesive composition not containing enzymatic oxidizing agent or chemical cross-linking agent comprises bioadhesive polyphenolic protein, a polymer, fine filaments, optionally a non-enzymatic oxidizing agent, and a filler protein |
Country Status (1)
Country | Link |
---|---|
SE (1) | SE516266C2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112409974B (en) * | 2020-11-19 | 2021-12-21 | 江南大学 | Amphiphilic bio-based degradable underwater adhesive and preparation method and application thereof |
-
1999
- 1999-12-17 SE SE9904650A patent/SE516266C2/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE516266C2 (en) | 2001-12-10 |
SE9904650D0 (en) | 1999-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |