SE9901115D0 - Nucleotide sequences - Google Patents
Nucleotide sequencesInfo
- Publication number
- SE9901115D0 SE9901115D0 SE9901115A SE9901115A SE9901115D0 SE 9901115 D0 SE9901115 D0 SE 9901115D0 SE 9901115 A SE9901115 A SE 9901115A SE 9901115 A SE9901115 A SE 9901115A SE 9901115 D0 SE9901115 D0 SE 9901115D0
- Authority
- SE
- Sweden
- Prior art keywords
- protein kinase
- gamma
- polypeptides
- nucleic acid
- acid molecules
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 101000798007 Homo sapiens RAC-gamma serine/threonine-protein kinase Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 108010045717 Proto-Oncogene Proteins c-akt Proteins 0.000 abstract 1
- 102000005765 Proto-Oncogene Proteins c-akt Human genes 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000004155 insulin signaling pathway Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Enzymes And Modification Thereof (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention relates to human protein kinase B gamma polypeptides and to nucleic acid molecules coding for such polypeptides. The invention further relates to vectors and cells comprising said nucleic acid molecules, as well as to methods for screening test compounds which affect the insulin signaling pathway. In contrast to the previously known protein kinase B gamma from rat brain, the human protein kinase B gamma polypeptides comprise two activating phosphorylation residues; Thr<305> and Ser<472>.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9901115A SE9901115D0 (en) | 1999-03-25 | 1999-03-25 | Nucleotide sequences |
| EP00921244A EP1163327A1 (en) | 1999-03-25 | 2000-03-23 | Human protein kinase b gamma polypeptides and a method for disrupting protein kinase b gamma in a non-human |
| CA002368379A CA2368379A1 (en) | 1999-03-25 | 2000-03-23 | Human protein kinase b.gamma. polypeptides and a method for disrupting protein kinase b.gamma. in a non-human |
| AU41581/00A AU4158100A (en) | 1999-03-25 | 2000-03-23 | Human protein kinase bgamma polypeptides and a method for disrupting protein kinase bgamma in a non-human |
| PCT/SE2000/000571 WO2000058446A1 (en) | 1999-03-25 | 2000-03-23 | HUMAN PROTEIN KINASE Bη POLYPEPTIDES AND A METHOD FOR DISRUPTING PROTEIN KINASE Bη IN A NON-HUMAN |
| JP2000608727A JP2002539823A (en) | 1999-03-25 | 2000-03-23 | Human protein kinase Bγ polypeptide and method for degrading non-human protein kinase Bγ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9901115A SE9901115D0 (en) | 1999-03-25 | 1999-03-25 | Nucleotide sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9901115D0 true SE9901115D0 (en) | 1999-03-25 |
Family
ID=20415022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9901115A SE9901115D0 (en) | 1999-03-25 | 1999-03-25 | Nucleotide sequences |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1163327A1 (en) |
| JP (1) | JP2002539823A (en) |
| AU (1) | AU4158100A (en) |
| CA (1) | CA2368379A1 (en) |
| SE (1) | SE9901115D0 (en) |
| WO (1) | WO2000058446A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997046669A1 (en) * | 1996-06-07 | 1997-12-11 | Amylin Pharmaceuticals, Inc. | Transgenic mammals lacking expression of amylin |
| US5814500A (en) * | 1996-10-31 | 1998-09-29 | The Johns Hopkins University School Of Medicine | Delivery construct for antisense nucleic acids and methods of use |
-
1999
- 1999-03-25 SE SE9901115A patent/SE9901115D0/en unknown
-
2000
- 2000-03-23 CA CA002368379A patent/CA2368379A1/en not_active Abandoned
- 2000-03-23 AU AU41581/00A patent/AU4158100A/en not_active Abandoned
- 2000-03-23 EP EP00921244A patent/EP1163327A1/en not_active Withdrawn
- 2000-03-23 JP JP2000608727A patent/JP2002539823A/en active Pending
- 2000-03-23 WO PCT/SE2000/000571 patent/WO2000058446A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000058446A1 (en) | 2000-10-05 |
| AU4158100A (en) | 2000-10-16 |
| CA2368379A1 (en) | 2000-10-05 |
| JP2002539823A (en) | 2002-11-26 |
| EP1163327A1 (en) | 2001-12-19 |
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