SE9704723D0 - ligands - Google Patents

ligands

Info

Publication number
SE9704723D0
SE9704723D0 SE9704723A SE9704723A SE9704723D0 SE 9704723 D0 SE9704723 D0 SE 9704723D0 SE 9704723 A SE9704723 A SE 9704723A SE 9704723 A SE9704723 A SE 9704723A SE 9704723 D0 SE9704723 D0 SE 9704723D0
Authority
SE
Sweden
Prior art keywords
ligands
intercalative
partly
agents
fomula
Prior art date
Application number
SE9704723A
Other languages
Swedish (sv)
Inventor
Ulrica Sehlstedt
Palok Aich
Jan Bergman
Hans Vallberg
Bengt Norden
Astrid Graeslund
Original Assignee
Leif J I Lundblad
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leif J I Lundblad filed Critical Leif J I Lundblad
Priority to SE9704723A priority Critical patent/SE9704723D0/en
Publication of SE9704723D0 publication Critical patent/SE9704723D0/en
Priority to IL13652598A priority patent/IL136525A0/en
Priority to APAP/P/2000/001835A priority patent/AP2000001835A0/en
Priority to JP2000538695A priority patent/JP2002508325A/en
Priority to PCT/SE1998/002340 priority patent/WO1999030712A1/en
Priority to AU18990/99A priority patent/AU1899099A/en
Priority to EP98963727A priority patent/EP1037638A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Agents for stabilizing natural or backbone modified DNA and RNA triplexes and hybrids thereof by partly intercalative, partly non-intercalative binding wherein the agent is a compound of fomula (I) wherein n = 2 or 3 and x is 1 or 2. Use of the ligands as antigene/antisense enhancing agents and in preparing drugs for treating retroviral infections are also described.
SE9704723A 1997-12-17 1997-12-17 ligands SE9704723D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE9704723A SE9704723D0 (en) 1997-12-17 1997-12-17 ligands
IL13652598A IL136525A0 (en) 1997-12-17 1998-12-16 Agents
APAP/P/2000/001835A AP2000001835A0 (en) 1997-12-17 1998-12-16 Agents.
JP2000538695A JP2002508325A (en) 1997-12-17 1998-12-16 Medicine
PCT/SE1998/002340 WO1999030712A1 (en) 1997-12-17 1998-12-16 Agents
AU18990/99A AU1899099A (en) 1997-12-17 1998-12-16 Agents
EP98963727A EP1037638A1 (en) 1997-12-17 1998-12-16 Agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704723A SE9704723D0 (en) 1997-12-17 1997-12-17 ligands

Publications (1)

Publication Number Publication Date
SE9704723D0 true SE9704723D0 (en) 1997-12-17

Family

ID=20409439

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9704723A SE9704723D0 (en) 1997-12-17 1997-12-17 ligands

Country Status (7)

Country Link
EP (1) EP1037638A1 (en)
JP (1) JP2002508325A (en)
AP (1) AP2000001835A0 (en)
AU (1) AU1899099A (en)
IL (1) IL136525A0 (en)
SE (1) SE9704723D0 (en)
WO (1) WO1999030712A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022002898A1 (en) * 2020-06-29 2022-01-06 Vironova Medical Ab 6h-indolo(2,3-b)quinoxaline derivatives useful in therapy in particular in a virus infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8600260D0 (en) * 1986-01-21 1986-01-21 Lundblad Leif SUBSTITUTED INDOLOKINOXALINES
SE504289C2 (en) * 1994-06-23 1996-12-23 Leif J I Lundblad Use of certain indolo-2,3b-quinoxalins for the preparation of a drug for inhibiting the enzyme HIV integrase
SE504862C2 (en) * 1994-12-27 1997-05-20 Leif J I Lundblad Use of certain indolo- §2,3b-quinoxalines for the preparation of a drug for the protection of DNA in the initiation and / or promotional phase of carcinogenesis and for the prevention of oxidative stress in patients with diseases related to free radicals

Also Published As

Publication number Publication date
AU1899099A (en) 1999-07-05
WO1999030712A1 (en) 1999-06-24
AP2000001835A0 (en) 2000-06-30
EP1037638A1 (en) 2000-09-27
IL136525A0 (en) 2001-06-14
JP2002508325A (en) 2002-03-19

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