SE9702188D0 - Improved method for site-selective glycosylation - Google Patents

Improved method for site-selective glycosylation

Info

Publication number
SE9702188D0
SE9702188D0 SE9702188A SE9702188A SE9702188D0 SE 9702188 D0 SE9702188 D0 SE 9702188D0 SE 9702188 A SE9702188 A SE 9702188A SE 9702188 A SE9702188 A SE 9702188A SE 9702188 D0 SE9702188 D0 SE 9702188D0
Authority
SE
Sweden
Prior art keywords
site
improved method
selective glycosylation
polypeptide
protein
Prior art date
Application number
SE9702188A
Other languages
Swedish (sv)
Inventor
Per Ahlberg
Lars Baltzer
Original Assignee
Holdingbolaget Vid Goeteborgs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Holdingbolaget Vid Goeteborgs filed Critical Holdingbolaget Vid Goeteborgs
Priority to SE9702188A priority Critical patent/SE9702188D0/en
Publication of SE9702188D0 publication Critical patent/SE9702188D0/en
Priority to PCT/SE1998/001008 priority patent/WO1998055501A1/en
Priority to AU80444/98A priority patent/AU8044498A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

The present invention is related to an improved method for site-selective glycosylation of folded polypeptides and proteins comprising an imidazole function, preferably histidine, in position i flanked by at least one functional group, such as lysine, ornithine and/or a diaminobutyric acid residue, in positions i+4 and/or i-3, according to which a carbohydrate residue is incorporated into the polypeptide or protein by reacting a p-nitrophenyl ester of a non-protected carbohydrate with the polypeptide or the protein.
SE9702188A 1997-06-06 1997-06-06 Improved method for site-selective glycosylation SE9702188D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9702188A SE9702188D0 (en) 1997-06-06 1997-06-06 Improved method for site-selective glycosylation
PCT/SE1998/001008 WO1998055501A1 (en) 1997-06-06 1998-05-28 Improved method for site-selective glycosylation
AU80444/98A AU8044498A (en) 1997-06-06 1998-05-28 Improved method for site-selective glycosylation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702188A SE9702188D0 (en) 1997-06-06 1997-06-06 Improved method for site-selective glycosylation

Publications (1)

Publication Number Publication Date
SE9702188D0 true SE9702188D0 (en) 1997-06-06

Family

ID=20407299

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9702188A SE9702188D0 (en) 1997-06-06 1997-06-06 Improved method for site-selective glycosylation

Country Status (3)

Country Link
AU (1) AU8044498A (en)
SE (1) SE9702188D0 (en)
WO (1) WO1998055501A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0001698D0 (en) * 2000-05-05 2000-05-05 A & Science Invest Ab Site-selective acyl transfer
SE0202473D0 (en) 2001-11-21 2002-08-19 A & Science Ab Site selective acylation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9603323D0 (en) * 1996-05-14 1996-09-12 Ahlberg Catalytic method and structure

Also Published As

Publication number Publication date
AU8044498A (en) 1998-12-21
WO1998055501A1 (en) 1998-12-10
WO1998055501A9 (en) 1999-07-15

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