SE9700620D0 - Cyclic peptides with selectivity for MSH receptor subtypes - Google Patents

Cyclic peptides with selectivity for MSH receptor subtypes

Info

Publication number
SE9700620D0
SE9700620D0 SE9700620A SE9700620A SE9700620D0 SE 9700620 D0 SE9700620 D0 SE 9700620D0 SE 9700620 A SE9700620 A SE 9700620A SE 9700620 A SE9700620 A SE 9700620A SE 9700620 D0 SE9700620 D0 SE 9700620D0
Authority
SE
Sweden
Prior art keywords
lrg
release
selectivity
secretion
peptides
Prior art date
Application number
SE9700620A
Other languages
Swedish (sv)
Inventor
Ruta Muceniece
Felikss Mutulis
Peteris Prusis
Helgi-Birgir Schioeth
Jarl Wickberg
Original Assignee
Wapharm Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wapharm Ab filed Critical Wapharm Ab
Priority to SE9700620A priority Critical patent/SE9700620D0/en
Publication of SE9700620D0 publication Critical patent/SE9700620D0/en
Priority to AU61274/98A priority patent/AU6127498A/en
Priority to EP98905907A priority patent/EP1025127A1/en
Priority to PCT/SE1998/000270 priority patent/WO1998037097A1/en

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cyclic MC-receptor activating and/or blocking peptides of general formula (I) in which LRG is a large aminoacid and L is 26-29 membered linker connecting LRG and Trp are useful for treating conditions related to eating, body weight, motivation, learning, memory, behaviour, inflammation, body temperature, pain perception, blood pressure, heart rate, vascular tone, natriuresis, brain blood flow, nerve growth, placental development, aldosteron synthesis and release, thyroxin release, spermatogenesis, ovarian weight, prolacting and FSH secretion, uterine bleeding in women, sebum and pheromone secretion, blood glucose levels, intrauterine foetal growth, as well as other events related to parturition, and to afford neuroprotection. The novel peptides can also be labeled and be incorporated into pharmaceutical compositions.
SE9700620A 1997-02-21 1997-02-21 Cyclic peptides with selectivity for MSH receptor subtypes SE9700620D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9700620A SE9700620D0 (en) 1997-02-21 1997-02-21 Cyclic peptides with selectivity for MSH receptor subtypes
AU61274/98A AU6127498A (en) 1997-02-21 1998-02-16 Msh-receptor subtype selective cyclic peptides
EP98905907A EP1025127A1 (en) 1997-02-21 1998-02-16 Msh-receptor subtype selective cyclic peptides
PCT/SE1998/000270 WO1998037097A1 (en) 1997-02-21 1998-02-16 Msh-receptor subtype selective cyclic peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9700620A SE9700620D0 (en) 1997-02-21 1997-02-21 Cyclic peptides with selectivity for MSH receptor subtypes

Publications (1)

Publication Number Publication Date
SE9700620D0 true SE9700620D0 (en) 1997-02-21

Family

ID=20405880

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9700620A SE9700620D0 (en) 1997-02-21 1997-02-21 Cyclic peptides with selectivity for MSH receptor subtypes

Country Status (4)

Country Link
EP (1) EP1025127A1 (en)
AU (1) AU6127498A (en)
SE (1) SE9700620D0 (en)
WO (1) WO1998037097A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9827500D0 (en) * 1998-12-14 1999-02-10 Wapharm Ab Compounds for control of eating, growth and body weight
CZ20013407A3 (en) 1999-03-29 2002-02-13 The Procter & Gamble Company Cyclic peptide analog and preparation thereof
JP2003534240A (en) 2000-01-18 2003-11-18 メルク エンド カムパニー インコーポレーテッド Cyclic peptides that are potent selective melanocortin-4 receptor antagonists
EA200500087A1 (en) 2000-06-27 2005-06-30 Тайсо Фармасьютикал Ко., Лтд. DERIVATIVES OF PIPERAZINE
PT2286825T (en) 2005-07-08 2017-01-02 Ipsen Pharma Sas Melanocortin receptor ligands
EP1915168A4 (en) * 2005-07-08 2010-03-31 Ipsen Pharma Ligands of melanocortin receptors
US9005575B2 (en) 2009-06-12 2015-04-14 Stc.Unm Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptide for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485039A (en) * 1982-06-11 1984-11-27 University Patents, Inc. Synthetic analogues of α-melanotropin
US4649191A (en) * 1984-05-10 1987-03-10 Gibson-Stephens Neuropharmaceuticals, Inc. Conformationally constrained alpha-melanotropin analogs with specific central nervous system activity

Also Published As

Publication number Publication date
WO1998037097A1 (en) 1998-08-27
AU6127498A (en) 1998-09-09
EP1025127A1 (en) 2000-08-09

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