SE9600046D0 - New pharmaceutical formulation - Google Patents
New pharmaceutical formulationInfo
- Publication number
- SE9600046D0 SE9600046D0 SE9600046A SE9600046A SE9600046D0 SE 9600046 D0 SE9600046 D0 SE 9600046D0 SE 9600046 A SE9600046 A SE 9600046A SE 9600046 A SE9600046 A SE 9600046A SE 9600046 D0 SE9600046 D0 SE 9600046D0
- Authority
- SE
- Sweden
- Prior art keywords
- beads
- furosemide
- minutes
- controlled release
- pharmaceutical formulation
- Prior art date
Links
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to controlled release beads comprising a core of an insoluble or soluble inert material provided with a layer of furosemide dispersed in a hydrophilic polymer and a specific outer membrane for controlled release of the furosemide whereby the membrane comprises 1) a film former selected from ethyl cellulose and copolymerisates of acrylic and methacrylic acid esters and 2) at least one hydrophilic polymer selected from polyvinylpyrrolidone, hydroxypropyl cellulose and polyalkylene glycols; in that the amount of the outer membrane is between 35 and 65 % (w/w) based on the dry layered core; and in that the release profile of furosemide is not more than 30 % after 60 minutes, not more than 44 % after 120 minutes and more than 80 % after 360 minutes. The present invention also refers to a process for the preparation of said controlled release beads, a pharmaceutical formulation comprising said beads and the use of said beads for treatment of cardiovascular diseases such as hypertension, congestive heart failure and oedema.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9600046A SE9600046D0 (en) | 1996-01-05 | 1996-01-05 | New pharmaceutical formulation |
PCT/SE1996/001734 WO1997025028A1 (en) | 1996-01-05 | 1996-12-20 | Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads |
AU13238/97A AU1323897A (en) | 1996-01-05 | 1996-12-20 | Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads |
ZA9610888A ZA9610888B (en) | 1996-01-05 | 1996-12-23 | Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads |
MA24443A MA26416A1 (en) | 1996-01-05 | 1996-12-26 | CONTROLLED RELEASE PHARMACEUTICAL PEARLS CONTAINING FUROSEMIDE AND A COMPOSITION MADE WITH SAID PEARLS. |
TNTNSN97001A TNSN97001A1 (en) | 1996-01-05 | 1997-01-03 | CONTROLLED RELEASE PHARMACEUTICAL PEARLS CONTAINING FUROSEMIDE, AND A COMPOSITION MADE WITH SAID PEARLS. |
HRP970004 HRP970004A2 (en) | 1996-01-05 | 1997-01-03 | Pharmaceutically controlled release of beads comprising furosemide and a formulation containing said controlled release beads |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9600046A SE9600046D0 (en) | 1996-01-05 | 1996-01-05 | New pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9600046D0 true SE9600046D0 (en) | 1996-01-05 |
Family
ID=20400947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9600046A SE9600046D0 (en) | 1996-01-05 | 1996-01-05 | New pharmaceutical formulation |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU1323897A (en) |
HR (1) | HRP970004A2 (en) |
MA (1) | MA26416A1 (en) |
SE (1) | SE9600046D0 (en) |
TN (1) | TNSN97001A1 (en) |
WO (1) | WO1997025028A1 (en) |
ZA (1) | ZA9610888B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK287674B6 (en) | 1998-11-02 | 2011-05-06 | Elan Pharma International Limited | Multiparticulate modified release composition comprising methylphenidate, solid oral dosage form containing thereof and its use |
FR2796840B1 (en) | 1999-07-26 | 2003-06-20 | Ethypharm Lab Prod Ethiques | LOW-DOSE TABLETS AND METHOD OF PREPARATION |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
EP2295043A1 (en) | 1999-10-29 | 2011-03-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
AU2738302A (en) | 2000-10-30 | 2002-05-15 | Euro Celtique Sa | Controlled release hydrocodone formulations |
US20030091633A1 (en) * | 2001-11-15 | 2003-05-15 | John Kelly | Methods and compositions for use of (S)-bisoprolol |
IL160095A0 (en) * | 2004-01-28 | 2004-06-20 | Yissum Res Dev Co | Formulations for poorly soluble drugs |
SI1669074T1 (en) * | 2004-12-01 | 2010-10-29 | Par Pharmaceuticals Inc | Use of megestrol acetate for improving heart function and the treatment of heart insufficiency |
WO2009145716A1 (en) * | 2008-05-28 | 2009-12-03 | Astrazeneca Ab | New pharmaceutical formulation useful in gerd therapy |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4938968A (en) * | 1988-07-26 | 1990-07-03 | Norjec Development Associates, Inc. | Controlled release indomethacin |
CA1338596C (en) * | 1988-09-27 | 1996-09-17 | Hiroyoshi Koyama | Granules having core and their production |
-
1996
- 1996-01-05 SE SE9600046A patent/SE9600046D0/en unknown
- 1996-12-20 AU AU13238/97A patent/AU1323897A/en not_active Abandoned
- 1996-12-20 WO PCT/SE1996/001734 patent/WO1997025028A1/en active Application Filing
- 1996-12-23 ZA ZA9610888A patent/ZA9610888B/en unknown
- 1996-12-26 MA MA24443A patent/MA26416A1/en unknown
-
1997
- 1997-01-03 TN TNTNSN97001A patent/TNSN97001A1/en unknown
- 1997-01-03 HR HRP970004 patent/HRP970004A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1997025028A1 (en) | 1997-07-17 |
AU1323897A (en) | 1997-08-01 |
TNSN97001A1 (en) | 2005-03-15 |
MA26416A1 (en) | 2004-12-20 |
HRP970004A2 (en) | 1998-04-30 |
ZA9610888B (en) | 1997-07-07 |
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