SE9600046D0 - New pharmaceutical formulation - Google Patents

New pharmaceutical formulation

Info

Publication number
SE9600046D0
SE9600046D0 SE9600046A SE9600046A SE9600046D0 SE 9600046 D0 SE9600046 D0 SE 9600046D0 SE 9600046 A SE9600046 A SE 9600046A SE 9600046 A SE9600046 A SE 9600046A SE 9600046 D0 SE9600046 D0 SE 9600046D0
Authority
SE
Sweden
Prior art keywords
beads
furosemide
minutes
controlled release
pharmaceutical formulation
Prior art date
Application number
SE9600046A
Other languages
Swedish (sv)
Inventor
Hans Arwidsson
Maria Eriksson
Lars Stubberud
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9600046A priority Critical patent/SE9600046D0/en
Publication of SE9600046D0 publication Critical patent/SE9600046D0/en
Priority to PCT/SE1996/001734 priority patent/WO1997025028A1/en
Priority to AU13238/97A priority patent/AU1323897A/en
Priority to ZA9610888A priority patent/ZA9610888B/en
Priority to MA24443A priority patent/MA26416A1/en
Priority to TNTNSN97001A priority patent/TNSN97001A1/en
Priority to HRP970004 priority patent/HRP970004A2/en

Links

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to controlled release beads comprising a core of an insoluble or soluble inert material provided with a layer of furosemide dispersed in a hydrophilic polymer and a specific outer membrane for controlled release of the furosemide whereby the membrane comprises 1) a film former selected from ethyl cellulose and copolymerisates of acrylic and methacrylic acid esters and 2) at least one hydrophilic polymer selected from polyvinylpyrrolidone, hydroxypropyl cellulose and polyalkylene glycols; in that the amount of the outer membrane is between 35 and 65 % (w/w) based on the dry layered core; and in that the release profile of furosemide is not more than 30 % after 60 minutes, not more than 44 % after 120 minutes and more than 80 % after 360 minutes. The present invention also refers to a process for the preparation of said controlled release beads, a pharmaceutical formulation comprising said beads and the use of said beads for treatment of cardiovascular diseases such as hypertension, congestive heart failure and oedema.
SE9600046A 1996-01-05 1996-01-05 New pharmaceutical formulation SE9600046D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE9600046A SE9600046D0 (en) 1996-01-05 1996-01-05 New pharmaceutical formulation
PCT/SE1996/001734 WO1997025028A1 (en) 1996-01-05 1996-12-20 Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads
AU13238/97A AU1323897A (en) 1996-01-05 1996-12-20 Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads
ZA9610888A ZA9610888B (en) 1996-01-05 1996-12-23 Pharmaceutical controlled release beads comprising furosemide and a formulation containing said controlled release beads
MA24443A MA26416A1 (en) 1996-01-05 1996-12-26 CONTROLLED RELEASE PHARMACEUTICAL PEARLS CONTAINING FUROSEMIDE AND A COMPOSITION MADE WITH SAID PEARLS.
TNTNSN97001A TNSN97001A1 (en) 1996-01-05 1997-01-03 CONTROLLED RELEASE PHARMACEUTICAL PEARLS CONTAINING FUROSEMIDE, AND A COMPOSITION MADE WITH SAID PEARLS.
HRP970004 HRP970004A2 (en) 1996-01-05 1997-01-03 Pharmaceutically controlled release of beads comprising furosemide and a formulation containing said controlled release beads

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9600046A SE9600046D0 (en) 1996-01-05 1996-01-05 New pharmaceutical formulation

Publications (1)

Publication Number Publication Date
SE9600046D0 true SE9600046D0 (en) 1996-01-05

Family

ID=20400947

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9600046A SE9600046D0 (en) 1996-01-05 1996-01-05 New pharmaceutical formulation

Country Status (7)

Country Link
AU (1) AU1323897A (en)
HR (1) HRP970004A2 (en)
MA (1) MA26416A1 (en)
SE (1) SE9600046D0 (en)
TN (1) TNSN97001A1 (en)
WO (1) WO1997025028A1 (en)
ZA (1) ZA9610888B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287674B6 (en) 1998-11-02 2011-05-06 Elan Pharma International Limited Multiparticulate modified release composition comprising methylphenidate, solid oral dosage form containing thereof and its use
FR2796840B1 (en) 1999-07-26 2003-06-20 Ethypharm Lab Prod Ethiques LOW-DOSE TABLETS AND METHOD OF PREPARATION
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP2295043A1 (en) 1999-10-29 2011-03-16 Euro-Celtique S.A. Controlled release hydrocodone formulations
AU2738302A (en) 2000-10-30 2002-05-15 Euro Celtique Sa Controlled release hydrocodone formulations
US20030091633A1 (en) * 2001-11-15 2003-05-15 John Kelly Methods and compositions for use of (S)-bisoprolol
IL160095A0 (en) * 2004-01-28 2004-06-20 Yissum Res Dev Co Formulations for poorly soluble drugs
SI1669074T1 (en) * 2004-12-01 2010-10-29 Par Pharmaceuticals Inc Use of megestrol acetate for improving heart function and the treatment of heart insufficiency
WO2009145716A1 (en) * 2008-05-28 2009-12-03 Astrazeneca Ab New pharmaceutical formulation useful in gerd therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US4938968A (en) * 1988-07-26 1990-07-03 Norjec Development Associates, Inc. Controlled release indomethacin
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production

Also Published As

Publication number Publication date
WO1997025028A1 (en) 1997-07-17
AU1323897A (en) 1997-08-01
TNSN97001A1 (en) 2005-03-15
MA26416A1 (en) 2004-12-20
HRP970004A2 (en) 1998-04-30
ZA9610888B (en) 1997-07-07

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