SE9102068D0 - Derivatives of inositol, preparations containing them and their use - Google Patents
Derivatives of inositol, preparations containing them and their useInfo
- Publication number
- SE9102068D0 SE9102068D0 SE9102068A SE9102068A SE9102068D0 SE 9102068 D0 SE9102068 D0 SE 9102068D0 SE 9102068 A SE9102068 A SE 9102068A SE 9102068 A SE9102068 A SE 9102068A SE 9102068 D0 SE9102068 D0 SE 9102068D0
- Authority
- SE
- Sweden
- Prior art keywords
- pct
- chemical structure
- hydrogen
- inositol
- derivatives
- Prior art date
Links
- 150000004001 inositols Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 1
- 229960000367 inositol Drugs 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4075—Esters with hydroxyalkyl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9102068A SE9102068L (sv) | 1991-07-03 | 1991-07-03 | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
JP05502180A JP3102798B2 (ja) | 1991-07-03 | 1992-06-30 | イノシトールの誘導体、それを含む製剤及びそれらの使用法 |
US07/955,708 US5306841A (en) | 1991-07-03 | 1992-06-30 | Derivatives of inositol, preparations containing them and their use |
EP92914702A EP0593595B1 (en) | 1991-07-03 | 1992-06-30 | Derivatives of inositol, preparations containing them and their use |
DE69230532T DE69230532T2 (de) | 1991-07-03 | 1992-06-30 | Inositolderivate, sie enthaltende präparate und ihre herstellung |
AT92914702T ATE188478T1 (de) | 1991-07-03 | 1992-06-30 | Inositolderivate, sie enthaltende präparate und ihre herstellung |
AU22915/92A AU2291592A (en) | 1991-07-03 | 1992-06-30 | Derivatives of inositol, preparations containing them and their use |
PCT/SE1992/000489 WO1993001197A1 (en) | 1991-07-03 | 1992-06-30 | Derivatives of inositol, preparations containing them and their use |
DK92914702T DK0593595T3 (da) | 1991-07-03 | 1992-06-30 | Derivater af inositol, præparater indeholdende dem samt deres anvendelse |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9102068A SE9102068L (sv) | 1991-07-03 | 1991-07-03 | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
Publications (2)
Publication Number | Publication Date |
---|---|
SE9102068D0 true SE9102068D0 (sv) | 1991-07-03 |
SE9102068L SE9102068L (sv) | 1993-01-04 |
Family
ID=20383238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9102068A SE9102068L (sv) | 1991-07-03 | 1991-07-03 | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
Country Status (9)
Country | Link |
---|---|
US (1) | US5306841A (sv) |
EP (1) | EP0593595B1 (sv) |
JP (1) | JP3102798B2 (sv) |
AT (1) | ATE188478T1 (sv) |
AU (1) | AU2291592A (sv) |
DE (1) | DE69230532T2 (sv) |
DK (1) | DK0593595T3 (sv) |
SE (1) | SE9102068L (sv) |
WO (1) | WO1993001197A1 (sv) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004043396A2 (en) * | 2002-11-09 | 2004-05-27 | Nobex Corporation | Modified carbamate-containing prodrugs and methods of synthesizing same |
US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
CN101102779A (zh) * | 2004-11-17 | 2008-01-09 | 乔安妮·麦克劳林 | 用于治疗蛋白聚集疾病的含鲨肌醇衍生物的组合物和方法 |
JP2009511568A (ja) * | 2005-10-13 | 2009-03-19 | ワラタ ファーマシューティカルズ, インコーポレイテッド | イノシトール誘導体、ならびに異常なタンパク質の折りたたみまたは凝集、あるいはアミロイドの形成、沈着、蓄積または残存を特徴とする疾患の処置におけるその使用 |
US20070197452A1 (en) * | 2006-02-17 | 2007-08-23 | Mclaurin Joanne | Treatment of amyloid-related diseases |
NZ571181A (en) * | 2006-03-09 | 2011-12-22 | Waratah Pharmaceuticals Inc | A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation |
WO2007134449A1 (en) * | 2006-05-19 | 2007-11-29 | Waratah Pharmaceuticals Inc. | Screening methods for amyloid beta modulators |
US20100173960A1 (en) * | 2006-09-21 | 2010-07-08 | Antonio Cruz | The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases |
WO2008061373A1 (en) * | 2006-11-24 | 2008-05-29 | Waratah Pharmaceuticals Inc. | Combination treatments for alzheimer's disease and similar diseases |
US20100144891A1 (en) * | 2007-04-12 | 2010-06-10 | Mclaurin Joanne | Use of cyclohexanehexol derivatives in the treatment of amyotrophic lateral sclerosis |
DK2148667T3 (da) * | 2007-04-12 | 2013-08-26 | Waratah Pharmaceuticals Inc | Anvendelse af cyclohexanhexolderivater til behandling af øjensygdomme |
CA2683548A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases |
WO2008124929A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF α-SYNUCLEINOPATHIES |
AU2009301603A1 (en) * | 2008-10-09 | 2010-04-15 | Waratah Pharmaceuticals Inc. | Use of scyllo-inositols for the treatment of macular degeneration-related disorders |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
US4585762A (en) * | 1982-07-30 | 1986-04-29 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, processes for use thereof and pharmaceutical composition of the same |
SE465951B (sv) * | 1984-10-23 | 1991-11-25 | Perstorp Ab | Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav |
SE8605063D0 (sv) * | 1986-11-26 | 1986-11-26 | Matti Siren | Derivatives of cyclohexane |
-
1991
- 1991-07-03 SE SE9102068A patent/SE9102068L/sv unknown
-
1992
- 1992-06-30 DK DK92914702T patent/DK0593595T3/da active
- 1992-06-30 EP EP92914702A patent/EP0593595B1/en not_active Expired - Lifetime
- 1992-06-30 AT AT92914702T patent/ATE188478T1/de active
- 1992-06-30 AU AU22915/92A patent/AU2291592A/en not_active Abandoned
- 1992-06-30 JP JP05502180A patent/JP3102798B2/ja not_active Expired - Fee Related
- 1992-06-30 WO PCT/SE1992/000489 patent/WO1993001197A1/en active IP Right Grant
- 1992-06-30 US US07/955,708 patent/US5306841A/en not_active Expired - Fee Related
- 1992-06-30 DE DE69230532T patent/DE69230532T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2291592A (en) | 1993-02-11 |
ATE188478T1 (de) | 2000-01-15 |
EP0593595A1 (en) | 1994-04-27 |
DE69230532D1 (de) | 2000-02-10 |
EP0593595B1 (en) | 2000-01-05 |
SE9102068L (sv) | 1993-01-04 |
US5306841A (en) | 1994-04-26 |
DK0593595T3 (da) | 2000-06-26 |
JPH06509092A (ja) | 1994-10-13 |
WO1993001197A1 (en) | 1993-01-21 |
JP3102798B2 (ja) | 2000-10-23 |
DE69230532T2 (de) | 2000-08-24 |
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