SE9003040L - ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF - Google Patents

ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF

Info

Publication number
SE9003040L
SE9003040L SE9003040A SE9003040A SE9003040L SE 9003040 L SE9003040 L SE 9003040L SE 9003040 A SE9003040 A SE 9003040A SE 9003040 A SE9003040 A SE 9003040A SE 9003040 L SE9003040 L SE 9003040L
Authority
SE
Sweden
Prior art keywords
analogues
cyclolinopeptide
medicament
amino acid
sequence
Prior art date
Application number
SE9003040A
Other languages
Swedish (sv)
Other versions
SE9003040D0 (en
SE467410B (en
Inventor
Z Wieczorek
Original Assignee
Ferring Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Ab filed Critical Ferring Ab
Priority to SE9003040A priority Critical patent/SE467410B/en
Publication of SE9003040D0 publication Critical patent/SE9003040D0/en
Priority to CA 2090859 priority patent/CA2090859A1/en
Priority to PCT/SE1991/000628 priority patent/WO1992005189A1/en
Priority to HU93847A priority patent/HU9300847D0/en
Priority to AU86531/91A priority patent/AU8653191A/en
Priority to EP19910917536 priority patent/EP0553133A1/en
Publication of SE9003040L publication Critical patent/SE9003040L/en
Publication of SE467410B publication Critical patent/SE467410B/en
Priority to FI931259A priority patent/FI931259A/en
Priority to NO931091A priority patent/NO931091D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

New analogues of Cyclolinopeptide A having a cyclic formula derived from the sequence of Cyclolinopeptide A (I) which sequence is extended between any two amino acid residues with the cystine derivative residue (II) in which X is selected from -H and -OH, and Y is selected from (a) and -H, wherein the amino acid residues are of L- or D-configuration, are disclosed. The above analogues can be used as medicaments, especially as immunosuppressive agents. The use of the above analogues for the preparation of a medicament for immunosuppressive treatment and pharmaceutical preparations comprising said analogues are also disclosed. A mammal, including man, in need of immunosuppressive treatment can be treated with a medicament comprising a pharmacologically effective amount of the above analogues.
SE9003040A 1990-09-25 1990-09-25 ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF SE467410B (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9003040A SE467410B (en) 1990-09-25 1990-09-25 ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF
CA 2090859 CA2090859A1 (en) 1990-09-25 1991-09-18 Analogues of cyclolinopeptide a and the use thereof
PCT/SE1991/000628 WO1992005189A1 (en) 1990-09-25 1991-09-18 Analogues of cyclolinopeptide a and the use thereof
HU93847A HU9300847D0 (en) 1990-09-25 1991-09-18 Cyclolinopeptone a-analogues and their utilization
AU86531/91A AU8653191A (en) 1990-09-25 1991-09-18 Analogues of cyclolinopeptide a and the use thereof
EP19910917536 EP0553133A1 (en) 1990-09-25 1991-09-18 Analogues of cyclolinopeptide a and the use thereof
FI931259A FI931259A (en) 1990-09-25 1993-03-22 ANALOGER AV CYCLOLINOPEPTID A OCH DERAS FRAMSTAELLNING
NO931091A NO931091D0 (en) 1990-09-25 1993-03-24 ANALOGS OF CYCLOIN Peptide A AND USE thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9003040A SE467410B (en) 1990-09-25 1990-09-25 ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF

Publications (3)

Publication Number Publication Date
SE9003040D0 SE9003040D0 (en) 1990-09-25
SE9003040L true SE9003040L (en) 1992-03-26
SE467410B SE467410B (en) 1992-07-13

Family

ID=20380440

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9003040A SE467410B (en) 1990-09-25 1990-09-25 ANALOGS OF CYCLOLINOPEPTIDE AND USE THEREOF

Country Status (7)

Country Link
EP (1) EP0553133A1 (en)
AU (1) AU8653191A (en)
CA (1) CA2090859A1 (en)
FI (1) FI931259A (en)
HU (1) HU9300847D0 (en)
SE (1) SE467410B (en)
WO (1) WO1992005189A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2583678A3 (en) 2004-06-24 2013-11-13 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8804640L (en) * 1988-12-23 1990-06-24 Ferring Ab MEDICINAL COMPREHENSIVE CYCLOLINOPEPTIDE A

Also Published As

Publication number Publication date
CA2090859A1 (en) 1992-03-26
HU9300847D0 (en) 1993-06-28
EP0553133A1 (en) 1993-08-04
WO1992005189A1 (en) 1992-04-02
SE9003040D0 (en) 1990-09-25
SE467410B (en) 1992-07-13
FI931259A0 (en) 1993-03-22
FI931259A (en) 1993-03-22
AU8653191A (en) 1992-04-15

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