SE8802084L - PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY - Google Patents

PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY

Info

Publication number
SE8802084L
SE8802084L SE8802084A SE8802084A SE8802084L SE 8802084 L SE8802084 L SE 8802084L SE 8802084 A SE8802084 A SE 8802084A SE 8802084 A SE8802084 A SE 8802084A SE 8802084 L SE8802084 L SE 8802084L
Authority
SE
Sweden
Prior art keywords
conjugated
antibody
bactericid
pharmaceutical preparation
caries
Prior art date
Application number
SE8802084A
Other languages
Swedish (sv)
Other versions
SE8802084D0 (en
SE461570B (en
Inventor
G Fredriksson
M Bergryd
Original Assignee
Rama Bio Link Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rama Bio Link Ab filed Critical Rama Bio Link Ab
Priority to SE8802084A priority Critical patent/SE461570B/en
Publication of SE8802084D0 publication Critical patent/SE8802084D0/en
Priority to EP89906837A priority patent/EP0419532A1/en
Priority to PCT/SE1989/000311 priority patent/WO1989011866A1/en
Priority to AU37635/89A priority patent/AU3763589A/en
Publication of SE8802084L publication Critical patent/SE8802084L/en
Publication of SE461570B publication Critical patent/SE461570B/en
Priority to DK289090A priority patent/DK161892C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A conjugated of a bactericide and an antibody directed against at least a certain type of dental plaque-forming and/or caries-forming bacteria, such as Streptococcus mutans is described. The bactericide of the conjugate is preferably an antibiotic, e.g. Netilmicin. Moreover, pharmaceutical preparations comprising a conjugate of the invention and a method of treating dental plaque and/or caries are described.
SE8802084A 1988-06-06 1988-06-06 PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY SE461570B (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
SE8802084A SE461570B (en) 1988-06-06 1988-06-06 PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY
EP89906837A EP0419532A1 (en) 1988-06-06 1989-06-02 A pharmaceutical preparation and a conjugate of a bactericide and an antibody directed against plaque forming or caries-inducing bacteria
PCT/SE1989/000311 WO1989011866A1 (en) 1988-06-06 1989-06-02 A pharmaceutical preparation and a conjugate of a bactericide and an antibody directed against plaque forming or caries-inducing bacteria
AU37635/89A AU3763589A (en) 1988-06-06 1989-06-02 A pharmaceutical preparation and a conjugate of a bactericide and an antibody directed against plaque forming or caries-inducing bacteria
DK289090A DK161892C (en) 1988-06-06 1990-12-05 PHARMACEUTICAL PREPARATION AND CONJUGATE OF A BACTERICIDE AND ANTIBODY AGAINST PLAQUE-forming OR CARIES-INducing BACTERIES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8802084A SE461570B (en) 1988-06-06 1988-06-06 PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY

Publications (3)

Publication Number Publication Date
SE8802084D0 SE8802084D0 (en) 1988-06-06
SE8802084L true SE8802084L (en) 1989-12-07
SE461570B SE461570B (en) 1990-03-05

Family

ID=20372517

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8802084A SE461570B (en) 1988-06-06 1988-06-06 PHARMACEUTICAL PREPARATION AND CONJUGATED BY A BACTERICID AND ANTIBODY

Country Status (5)

Country Link
EP (1) EP0419532A1 (en)
AU (1) AU3763589A (en)
DK (1) DK161892C (en)
SE (1) SE461570B (en)
WO (1) WO1989011866A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9021671D0 (en) * 1990-10-05 1990-11-21 Unilever Plc Delivery of agents
AU642979B2 (en) * 1990-03-21 1993-11-04 Quest International B.V. Utilization and delivery of enzymes
AU641736B2 (en) * 1990-03-21 1993-09-30 Quest International B.V. Delivery of agents
CN101002947B (en) * 2007-01-16 2010-08-25 湖南农业大学 Target medicine used for treating bacteriosis, and its preparing method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1433593A (en) * 1972-06-09 1976-04-28 Royal College Of Surgeons Conjugates
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4699784A (en) * 1986-02-25 1987-10-13 Center For Molecular Medicine & Immunology Tumoricidal methotrexate-antibody conjugate

Also Published As

Publication number Publication date
SE8802084D0 (en) 1988-06-06
DK289090D0 (en) 1990-12-05
DK161892B (en) 1991-08-26
AU3763589A (en) 1990-01-05
WO1989011866A1 (en) 1989-12-14
SE461570B (en) 1990-03-05
EP0419532A1 (en) 1991-04-03
DK289090A (en) 1990-12-05
DK161892C (en) 1992-03-09

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