SE8603838L - GENETICALLY PROCESSED MICRO-ORGANISMS FOR L-AMINO ACID PREPARATION - Google Patents

GENETICALLY PROCESSED MICRO-ORGANISMS FOR L-AMINO ACID PREPARATION

Info

Publication number
SE8603838L
SE8603838L SE8603838A SE8603838A SE8603838L SE 8603838 L SE8603838 L SE 8603838L SE 8603838 A SE8603838 A SE 8603838A SE 8603838 A SE8603838 A SE 8603838A SE 8603838 L SE8603838 L SE 8603838L
Authority
SE
Sweden
Prior art keywords
organisms
amino acid
acid preparation
strain
processed micro
Prior art date
Application number
SE8603838A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8603838D0 (en
Inventor
G G Lovinger
A W Hammond
Original Assignee
Grace W R & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grace W R & Co filed Critical Grace W R & Co
Publication of SE8603838D0 publication Critical patent/SE8603838D0/en
Publication of SE8603838L publication Critical patent/SE8603838L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A thermally stable transminase gene from Salmonella typhimurium (eg the AT sty 2 gene) is isolated and inserted into a multiple copy expression vector which is introduced into a suitable host microorganism strain eg E. coli S. typhimurium. L-amino acids can be produced by contacting the corresponding alpha- keto acid and an amino donor with the transformed strain or a portion or extract thereof. Activity is up to about thirty times that of the untransformed host strain.
SE8603838A 1985-09-19 1986-09-12 GENETICALLY PROCESSED MICRO-ORGANISMS FOR L-AMINO ACID PREPARATION SE8603838L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77781185A 1985-09-19 1985-09-19

Publications (2)

Publication Number Publication Date
SE8603838D0 SE8603838D0 (en) 1986-09-12
SE8603838L true SE8603838L (en) 1987-03-20

Family

ID=25111353

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8603838A SE8603838L (en) 1985-09-19 1986-09-12 GENETICALLY PROCESSED MICRO-ORGANISMS FOR L-AMINO ACID PREPARATION

Country Status (8)

Country Link
JP (1) JPS6269980A (en)
AU (1) AU6272286A (en)
DE (1) DE3631416A1 (en)
FR (1) FR2588015A1 (en)
GB (1) GB2180540A (en)
IT (1) IT1197240B (en)
NL (1) NL8602365A (en)
SE (1) SE8603838L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518907A (en) 1989-06-07 1996-05-21 Center For Innovative Technology Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway
JP6093551B2 (en) 2012-11-06 2017-03-08 株式会社貝印刃物開発センター razor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8301700D0 (en) * 1983-01-21 1983-02-23 Searle & Co Cloning and utilisation of aminotransferase genes
AU3187984A (en) * 1983-08-16 1985-02-21 Genentech Inc. Recombinant process for preparing l-amino acids
US4783403A (en) * 1984-02-08 1988-11-08 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-phenylalanine

Also Published As

Publication number Publication date
NL8602365A (en) 1987-04-16
SE8603838D0 (en) 1986-09-12
IT8621735A0 (en) 1986-09-17
GB2180540A (en) 1987-04-01
DE3631416A1 (en) 1987-05-27
FR2588015A1 (en) 1987-04-03
IT8621735A1 (en) 1988-03-17
JPS6269980A (en) 1987-03-31
GB8622666D0 (en) 1986-10-22
IT1197240B (en) 1988-11-30
AU6272286A (en) 1987-03-26

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Legal Events

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NAV Patent application has lapsed

Ref document number: 8603838-7

Effective date: 19900401