SE8504191D0 - ACETYLDICARNITINE - Google Patents

ACETYLDICARNITINE

Info

Publication number
SE8504191D0
SE8504191D0 SE8504191A SE8504191A SE8504191D0 SE 8504191 D0 SE8504191 D0 SE 8504191D0 SE 8504191 A SE8504191 A SE 8504191A SE 8504191 A SE8504191 A SE 8504191A SE 8504191 D0 SE8504191 D0 SE 8504191D0
Authority
SE
Sweden
Prior art keywords
chloride
treatment
senile
dichloride
acetyldicarnitine
Prior art date
Application number
SE8504191A
Other languages
Swedish (sv)
Other versions
SE8504191L (en
SE458857B (en
Inventor
G Francia
Original Assignee
Chemiosyntex Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemiosyntex Srl filed Critical Chemiosyntex Srl
Publication of SE8504191D0 publication Critical patent/SE8504191D0/en
Publication of SE8504191L publication Critical patent/SE8504191L/en
Publication of SE458857B publication Critical patent/SE458857B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

<IMAGE> Acetyldicarnitine dichloride activates the proteic metabolism and stimulates digestive secretions, displaying an anabolic and antianorexic action. It is also active on the senile and pre-senile cerebral involution syndromes and on cardiopathies. It may be prepared from carnitine chloride either (i) by treatment with thionyl chloride to form the intermolecular ester, dicarnitine dichloride, followed by acetylation or (ii) by esterification using the acyl chloride obtained from acetylcarnitine chloride by treatment with thionyl chloride. Pharmaceutical compositions containing it are described.
SE8504191A 1984-03-28 1985-09-10 ACETYLDICARNITINE DICHLORIDE, PROCEDURES FOR PREPARING THEREOF AND THERAPEUTIC COMPOSITION CONTAINING THESE SUBSTANCE SE458857B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8420277A IT1237343B (en) 1984-03-28 1984-03-28 ACETYLDICHARNITINE DICHLORHYDRATE, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Publications (3)

Publication Number Publication Date
SE8504191D0 true SE8504191D0 (en) 1985-09-10
SE8504191L SE8504191L (en) 1987-03-11
SE458857B SE458857B (en) 1989-05-16

Family

ID=11165364

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8504191A SE458857B (en) 1984-03-28 1985-09-10 ACETYLDICARNITINE DICHLORIDE, PROCEDURES FOR PREPARING THEREOF AND THERAPEUTIC COMPOSITION CONTAINING THESE SUBSTANCE

Country Status (12)

Country Link
JP (1) JPS6272655A (en)
AT (1) AT382365B (en)
AU (1) AU575995B2 (en)
BE (1) BE903270A (en)
CH (1) CH663784A5 (en)
DE (1) DE3533877A1 (en)
FR (1) FR2588001B1 (en)
GB (1) GB2180533B (en)
IT (1) IT1237343B (en)
NL (1) NL8502578A (en)
SE (1) SE458857B (en)
ZA (1) ZA857051B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1263013B (en) * 1992-10-20 1996-07-23 Avantgarde Spa ESTERS OF L-CARNITINE AND ALCANOYL L-CARNITINE WITH GLYCOLIC ACID OR ITS ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH AS FOR THE TREATMENT OF SKIN DISEASES.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB754873A (en) * 1953-05-08 1956-08-15 Laboratoires Labaz Soc D Dicarnitine dichloride and a process for the preparation thereof
IT1133010B (en) * 1980-05-15 1986-07-09 Sigma Tau Ind Farmaceuti THERAPUETIC METHOD FOR THE TREATMENT OF DIABETES AT YOUTH ONCE AND PHARMACEUTICAL COMPOSITION FOR THIS METHOD
IT1177874B (en) * 1984-07-04 1987-08-26 Sigma Tau Ind Farmaceuti ESTERS OF ACETYL CARNITINE, PROCEDURES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Also Published As

Publication number Publication date
AU4737985A (en) 1987-03-12
AU575995B2 (en) 1988-08-11
ATA272385A (en) 1986-07-15
JPS6272655A (en) 1987-04-03
FR2588001B1 (en) 1987-11-27
IT8420277A0 (en) 1984-03-28
SE8504191L (en) 1987-03-11
BE903270A (en) 1986-03-20
IT1237343B (en) 1993-05-31
GB8523376D0 (en) 1985-10-23
FR2588001A1 (en) 1987-04-03
CH663784A5 (en) 1988-01-15
GB2180533B (en) 1989-09-13
AT382365B (en) 1987-02-25
ZA857051B (en) 1986-03-13
SE458857B (en) 1989-05-16
NL8502578A (en) 1987-04-16
GB2180533A (en) 1987-04-01
DE3533877A1 (en) 1987-03-26

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