SE8501692D0 - NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS - Google Patents

NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS

Info

Publication number
SE8501692D0
SE8501692D0 SE8501692A SE8501692A SE8501692D0 SE 8501692 D0 SE8501692 D0 SE 8501692D0 SE 8501692 A SE8501692 A SE 8501692A SE 8501692 A SE8501692 A SE 8501692A SE 8501692 D0 SE8501692 D0 SE 8501692D0
Authority
SE
Sweden
Prior art keywords
group
hydrogen
atom
alkyl
beta
Prior art date
Application number
SE8501692A
Other languages
Swedish (sv)
Inventor
P H Andersson
P T Andersson
B I Axelsson
B A Thalen
J W Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of SE8501692D0 publication Critical patent/SE8501692D0/en
Priority to SE8501692A priority Critical patent/SE8501692D0/en
Application filed by Draco Ab filed Critical Draco Ab
Priority to IL78144A priority patent/IL78144A0/en
Priority to PH33572A priority patent/PH22578A/en
Priority to FI861274A priority patent/FI86190C/en
Priority to DK138486A priority patent/DK165880C/en
Priority to AR86303485A priority patent/AR243535A1/en
Priority to EP86850113A priority patent/EP0200692B1/en
Priority to JO19861478A priority patent/JO1478B1/en
Priority to AT86850113T priority patent/ATE67210T1/en
Priority to DE8686850113T priority patent/DE3681334D1/en
Priority to NZ215587A priority patent/NZ215587A/en
Priority to AU55566/86A priority patent/AU594330B2/en
Priority to CS862327A priority patent/CS266580B2/en
Priority to DD28874386A priority patent/DD244137A5/en
Priority to CA000505743A priority patent/CA1278293C/en
Priority to KR1019860002522A priority patent/KR860008207A/en
Priority to NO861312A priority patent/NO165679C/en
Priority to ZA862490A priority patent/ZA862490B/en
Priority to HU861424A priority patent/HU200782B/en
Priority to SU864027266A priority patent/SU1604161A3/en
Priority to US06/847,933 priority patent/US4804656A/en
Priority to JP61075678A priority patent/JPH0764869B2/en
Priority to ES553674A priority patent/ES8800261A1/en
Priority to IE87886A priority patent/IE58309B1/en
Priority to GR860901A priority patent/GR860901B/en
Priority to PT82339A priority patent/PT82339B/en
Priority to CN198686102263A priority patent/CN86102263A/en
Priority to PL1986258776A priority patent/PL148734B1/en
Priority to EG184/86A priority patent/EG18042A/en
Priority to NO864979A priority patent/NO864979L/en
Priority to MYPI87001993A priority patent/MY102057A/en
Priority to PH37056A priority patent/PH25535A/en
Priority to LV930865A priority patent/LV5526A3/en
Priority to LTRP952A priority patent/LT2258B/en

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  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention refers to compounds having anti-inflammatory activity characterized by the formula or a stereoisomeric component thereof, in which formula X1 represents a hydrogen, chlorine, bromine or fluorine atom; X2 represents a hydrogen, chlorine, bromine or fluorine atom; R1 represents a beta -hydroxy group, a beta -chlorine atom or an oxo group; R2 represents a hydrogen atom, a methylene group or an alpha - or beta -methyl group; R3 represents a hydrogen atom or an acyl group of 1 through 8 carbon atoms; R4 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group; R5 represents a hydrogen atom, a (C1-C5) alkyl group or a phenyl group; Y represents either CR7R8, O, S or NR9, where R7, R8 and R9 are selected from hydrogen or from straight or branched hydrocarbon chains having 1-8 carbon atoms or from a phenyl group. R6 represents a hydrogen; a methyl group; a phenyl or an alkenyl or cycloalkylene group optionally substituted by alkyl, nitro, carboxy, alkoxy, halogen, cyano, carbalkoxy and trifluoromethyl group(s); a (C1-C5) alkyl group substituted by at least one halogen atom; a saturated or unsaturated carbocyclic or heterocyclic (O, S, N) ring system containing 3-10 atoms in the ring system; a C1 alkyl group substituted by either one or two alicyclic or aromatic 3,4,5 or 6-numbered ring system(s) or one, two or three straight or branched alkyl or alkenyl group(s) of 1 through 18 carbon atoms; and represents a single or double bond. The invention also refers to a process and intermediates for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment of inflammatory conditions.
SE8501692A 1985-04-04 1985-04-04 NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS SE8501692D0 (en)

Priority Applications (34)

Application Number Priority Date Filing Date Title
SE8501692A SE8501692D0 (en) 1985-04-04 1985-04-04 NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS
IL78144A IL78144A0 (en) 1985-04-04 1986-03-14 Novel androstane-17beta-carboxylic acid esters
PH33572A PH22578A (en) 1985-04-04 1986-03-24 Novel androstane-17b-carboxylic acid esters
FI861274A FI86190C (en) 1985-04-04 1986-03-25 Analogous process for preparing a therapeutically effective androst an-17-carboxylic acid ester
DK138486A DK165880C (en) 1985-04-04 1986-03-25 ANDROSTAN-17BETA CARBOXYLIC ACID ESTERS, PROCEDURES FOR PREPARING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME
AR86303485A AR243535A1 (en) 1985-04-04 1986-03-26 A procedure for preparing new esters of androstan-17beta-carboxylic acid and intermediates, for use exclusively in this procedure.
DE8686850113T DE3681334D1 (en) 1985-04-04 1986-04-01 ANDROSTANE-17-BETA-CARBONIC ACID ESTER, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
EP86850113A EP0200692B1 (en) 1985-04-04 1986-04-01 Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them
JO19861478A JO1478B1 (en) 1985-04-04 1986-04-01 Novel androstane - 17B -Carboxylic acid esters
AT86850113T ATE67210T1 (en) 1985-04-04 1986-04-01 ANDROSTANE-17-BETA-CARBONATES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
NZ215587A NZ215587A (en) 1985-04-04 1986-04-02 3-oxoandrost-4-ene-17beta-carboxylic acid ester derivatives and pharmaceutical compositions
AU55566/86A AU594330B2 (en) 1985-04-04 1986-04-02 Novel androstane-17beta-carboxylic acid esters
CS862327A CS266580B2 (en) 1985-04-04 1986-04-02 Method of androstane-17 beta-carboxyl acid's new esters production
IE87886A IE58309B1 (en) 1985-04-04 1986-04-03 Novel androstane-17 beta-carboxylic acid esters
NO861312A NO165679C (en) 1985-04-04 1986-04-03 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW, THERAPEUTICALLY EFFECTIVE ANDROSTAN-17BETA-CARBOXYL ACID ESTERS.
CA000505743A CA1278293C (en) 1985-04-04 1986-04-03 Androstane-17 beta-carboxylic acid esters
KR1019860002522A KR860008207A (en) 1985-04-04 1986-04-03 Process for preparing novel androstane-17β-carboxylic acid ester
DD28874386A DD244137A5 (en) 1985-04-04 1986-04-03 METHOD FOR PRODUCING ANDROSTAN-17BETA-CARBONIC ACID ESTERS
ZA862490A ZA862490B (en) 1985-04-04 1986-04-03 Novel androstane-17beta-carboxylic acid esters
HU861424A HU200782B (en) 1985-04-04 1986-04-03 Process for producing new androstane-17beta-carboxylic acid esters and pharmaceutical compositions comprising same
SU864027266A SU1604161A3 (en) 1985-04-04 1986-04-03 Method of producing esters of androstane-17b-carbolic acid
US06/847,933 US4804656A (en) 1985-04-04 1986-04-03 Novel androstane-17β-carboxylic acid esters
JP61075678A JPH0764869B2 (en) 1985-04-04 1986-04-03 Novel androstan-17β-carboxylic acid ester
ES553674A ES8800261A1 (en) 1985-04-04 1986-04-03 Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them.
PL1986258776A PL148734B1 (en) 1985-04-04 1986-04-04 Method of obtaining novel derivatives of androstanocyrboxylic-17 beta acid
GR860901A GR860901B (en) 1985-04-04 1986-04-04 Novel androstane -17-b- carboxylic acid esters
PT82339A PT82339B (en) 1985-04-04 1986-04-04 METHOD FOR THE PREPARATION OF NEW ANDROSTAN-17 BETA-CARBOXYLIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CN198686102263A CN86102263A (en) 1985-04-04 1986-04-04 A kind of novel androstane-17's preparation
EG184/86A EG18042A (en) 1985-04-04 1986-04-30 Novel androstane-17beta-carboxylic acid esters
NO864979A NO864979L (en) 1985-04-04 1986-12-10 ANDROSTAN-17 BETA CARBOXYLIC ACID COMPOUNDS.
MYPI87001993A MY102057A (en) 1985-04-04 1987-09-28 Novel androstane-17b-carboxylic acid esters
PH37056A PH25535A (en) 1985-04-04 1988-06-13 Novel androstane-17beta-carboxylic acid esters
LV930865A LV5526A3 (en) 1985-04-04 1993-06-30 Sediment for obtaining androstan-17beta-carbohydrate esters
LTRP952A LT2258B (en) 1985-04-04 1993-09-06 ANDROSTANO-17BETA-CARBONINE SYRING ESTER

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8501692A SE8501692D0 (en) 1985-04-04 1985-04-04 NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS

Publications (1)

Publication Number Publication Date
SE8501692D0 true SE8501692D0 (en) 1985-04-04

Family

ID=20359774

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8501692A SE8501692D0 (en) 1985-04-04 1985-04-04 NOVEL ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS

Country Status (5)

Country Link
DD (1) DD244137A5 (en)
JO (1) JO1478B1 (en)
SE (1) SE8501692D0 (en)
SU (1) SU1604161A3 (en)
ZA (1) ZA862490B (en)

Also Published As

Publication number Publication date
ZA862490B (en) 1986-11-26
DD244137A5 (en) 1987-03-25
SU1604161A3 (en) 1990-10-30
JO1478B1 (en) 1988-03-10

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