SE8405710L - NEW 6-VINYL-FURO- (3,4-C) -PYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NEW 6-VINYL-FURO- (3,4-C) -PYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
SE8405710L
SE8405710L SE8405710A SE8405710A SE8405710L SE 8405710 L SE8405710 L SE 8405710L SE 8405710 A SE8405710 A SE 8405710A SE 8405710 A SE8405710 A SE 8405710A SE 8405710 L SE8405710 L SE 8405710L
Authority
SE
Sweden
Prior art keywords
furo
vinyl
preparation
new
pyridine derivatives
Prior art date
Application number
SE8405710A
Other languages
Swedish (sv)
Other versions
SE458116B (en
SE8405710D0 (en
Inventor
A Esanu
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of SE8405710D0 publication Critical patent/SE8405710D0/en
Publication of SE8405710L publication Critical patent/SE8405710L/en
Publication of SE458116B publication Critical patent/SE458116B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Abstract

This invention relates to new 1,3-dihydro-6-vinyl-7-hydroxy-furo-(3,5-c)-pyridine derivatives of the general formula: <IMAGE> wherein each of A1 and A2 independently represents various hydrocarbon substituents, to a process for the preparation of these compounds from the corresponding 7-chloromethyl derivative and to pharmaceutical composition containing them. The compounds are useful as diuretics.
SE8405710A 1983-11-16 1984-11-14 NEW 6-VINYL-FURO- (3,4-C) -PYRIDINE DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SE458116B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838330517A GB8330517D0 (en) 1983-11-16 1983-11-16 6-vinyl-furo-(3,4-c)pyridine derivatives

Publications (3)

Publication Number Publication Date
SE8405710D0 SE8405710D0 (en) 1984-11-14
SE8405710L true SE8405710L (en) 1985-05-17
SE458116B SE458116B (en) 1989-02-27

Family

ID=10551816

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8405710A SE458116B (en) 1983-11-16 1984-11-14 NEW 6-VINYL-FURO- (3,4-C) -PYRIDINE DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (25)

Country Link
US (1) US4569939A (en)
JP (1) JPS60112793A (en)
AT (1) AT391867B (en)
BE (1) BE900942A (en)
CA (1) CA1257271A (en)
CH (1) CH660738A5 (en)
DE (1) DE3442035A1 (en)
DK (1) DK157870C (en)
DZ (1) DZ701A1 (en)
ES (1) ES8600299A1 (en)
FI (1) FI79852C (en)
FR (2) FR2554719B1 (en)
GB (2) GB8330517D0 (en)
HK (1) HK36087A (en)
IE (1) IE58005B1 (en)
IT (1) IT1213246B (en)
LU (1) LU85635A1 (en)
MA (1) MA20259A1 (en)
MY (1) MY101721A (en)
NL (1) NL8403353A (en)
OA (1) OA07864A (en)
PT (1) PT79511B (en)
SE (1) SE458116B (en)
SG (1) SG6687G (en)
ZA (1) ZA848130B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
ES2075671T3 (en) * 1991-04-24 1995-10-01 Ciba Geigy Ag AQUEOUS, FLUID DISPERSIONS OF CORROSION INHIBITORS BASED ON POLYCARBOXYLIC ACIDS.
BR0008857A (en) 1999-03-08 2001-12-18 Medicure Inc Pyridoxal analogues for vitaminab-6 disorders
AU5840200A (en) * 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
EP1210117A2 (en) * 1999-08-24 2002-06-05 Medicure International Inc. Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
CA2401655C (en) 2000-02-29 2010-06-22 Medicure International Inc. Cardioprotective phosphonates and malonates
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
JP2003528146A (en) 2000-03-28 2003-09-24 メディキュア インターナショナル インコーポレイテッド Treatment of cerebrovascular disease
EP1299358B1 (en) 2000-07-07 2007-06-13 Medicure International Inc. Pyridoxine and pyridoxal analogues as cardiovascular therapeutics
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US20040121988A1 (en) * 2001-03-28 2004-06-24 Medicure International Inc. Treatment of cerebrovascular disease
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
CA2570048A1 (en) * 2004-07-07 2006-01-12 Medicure International Inc. Combination therapies employing platelet aggregation drugs
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
CA2585165A1 (en) * 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
US20070149485A1 (en) * 2005-11-28 2007-06-28 Medicure International, Inc. Selected dosage for the treatment of cardiovascular and related pathologies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
GB2008582B (en) * 1977-11-25 1982-04-28 Scras Pyridine derivative
IN156817B (en) * 1981-02-10 1985-11-09 Scras

Also Published As

Publication number Publication date
FR2554817A1 (en) 1985-05-17
DK542584A (en) 1985-05-17
FI844279L (en) 1985-05-17
GB8330517D0 (en) 1983-12-21
IE842930L (en) 1985-05-16
JPH0314315B2 (en) 1991-02-26
SE458116B (en) 1989-02-27
AT391867B (en) 1990-12-10
GB2149782B (en) 1986-10-22
ES537665A0 (en) 1985-09-16
MA20259A1 (en) 1985-07-01
GB8426490D0 (en) 1984-11-28
US4569939A (en) 1986-02-11
JPS60112793A (en) 1985-06-19
FI79852C (en) 1990-03-12
CH660738A5 (en) 1987-06-15
OA07864A (en) 1986-11-20
PT79511B (en) 1986-09-08
FI79852B (en) 1989-11-30
IT8423565A0 (en) 1984-11-14
NL8403353A (en) 1985-06-17
MY101721A (en) 1992-01-17
HK36087A (en) 1987-05-08
SE8405710D0 (en) 1984-11-14
GB2149782A (en) 1985-06-19
LU85635A1 (en) 1985-06-04
ES8600299A1 (en) 1985-09-16
FR2554817B1 (en) 1986-04-18
SG6687G (en) 1987-06-05
DE3442035A1 (en) 1985-05-30
FI844279A0 (en) 1984-11-01
DK157870C (en) 1990-08-06
ZA848130B (en) 1985-06-26
PT79511A (en) 1984-12-01
IT1213246B (en) 1989-12-14
FR2554719A1 (en) 1985-05-17
DK542584D0 (en) 1984-11-15
DZ701A1 (en) 2004-09-13
BE900942A (en) 1985-02-15
ATA364384A (en) 1990-06-15
IE58005B1 (en) 1993-06-02
DK157870B (en) 1990-02-26
CA1257271A (en) 1989-07-11
FR2554719B1 (en) 1986-06-06

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