SE8405450L - 1,4-DIHYDROPYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE - Google Patents

1,4-DIHYDROPYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Info

Publication number
SE8405450L
SE8405450L SE8405450A SE8405450A SE8405450L SE 8405450 L SE8405450 L SE 8405450L SE 8405450 A SE8405450 A SE 8405450A SE 8405450 A SE8405450 A SE 8405450A SE 8405450 L SE8405450 L SE 8405450L
Authority
SE
Sweden
Prior art keywords
atoms
carbon
preparation
pharmaceutical preparations
preparations containing
Prior art date
Application number
SE8405450A
Other languages
Swedish (sv)
Other versions
SE8405450D0 (en
Inventor
A Vogel
G Bormann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8405450D0 publication Critical patent/SE8405450D0/en
Publication of SE8405450L publication Critical patent/SE8405450L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Compounds having the formula (I), wherein R1 is hydrogen, cycloalkyl with 3 to 7 atoms of carbon, optionally substituted alkyl with 1 to 6 atoms of carbon; R2 and R4, independently from each other, represent hydrogen or alkyl with 1 to 6 atoms of carbon; R3 is hydrogen, alkyl with 1 to 25 atoms of carbon, nitro, trifluoromethyl, cyan, -COOR5, - COR6 or -S(O)nR7; Q is a completely insaturated ring system with at least 2 different ring hetero atoms of aromatic character. The derivatives are used as calcium antagonists.
SE8405450A 1983-11-01 1984-10-31 1,4-DIHYDROPYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE SE8405450L (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH589183 1983-11-01
CH589383 1983-11-01
CH589583 1983-11-01
CH357884 1984-07-24
CH358084 1984-07-24

Publications (2)

Publication Number Publication Date
SE8405450D0 SE8405450D0 (en) 1984-10-31
SE8405450L true SE8405450L (en) 1985-06-10

Family

ID=27509144

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8405450A SE8405450L (en) 1983-11-01 1984-10-31 1,4-DIHYDROPYRIDINE DERIVATIVES, PREPARATION OF THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Country Status (12)

Country Link
AU (1) AU3486884A (en)
BE (1) BE900874A (en)
DE (1) DE3438884A1 (en)
DK (1) DK517484A (en)
FR (1) FR2554109A1 (en)
GB (1) GB2148895A (en)
IL (1) IL73363A0 (en)
IT (1) IT1199214B (en)
LU (1) LU85621A1 (en)
NL (1) NL8403302A (en)
SE (1) SE8405450L (en)
WO (1) WO1985001940A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3420784A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 3-NITRO-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI64938C (en) * 1977-06-20 1984-02-10 Sandoz Ag PROCEDURE FOR THE FRAMEWORK OF THERAPEUTIC THERAPEUTIC BENSOX A- AND OX BENZOTIADIAZOLYL-1,4-DIHYDROPYRID DERIVATIVES
DE2752820A1 (en) * 1977-11-26 1979-05-31 Bayer Ag NEW NITRO-SUBSTITUTED 1,4-DIHYDROPYRIDINE, THE METHOD FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT
DE2949464A1 (en) * 1978-12-18 1980-06-26 Sandoz Ag BENZOXADIAZOLES AND BENZOTHIADIAZOLES, THEIR PRODUCTION AND USE
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines

Also Published As

Publication number Publication date
BE900874A (en) 1985-04-23
NL8403302A (en) 1985-06-03
IL73363A0 (en) 1985-01-31
IT1199214B (en) 1988-12-30
FR2554109A1 (en) 1985-05-03
LU85621A1 (en) 1985-07-17
IT8449079A0 (en) 1984-10-29
DE3438884A1 (en) 1985-05-09
GB8427443D0 (en) 1984-12-05
WO1985001940A1 (en) 1985-05-09
GB2148895A (en) 1985-06-05
IT8449079A1 (en) 1986-04-29
AU3486884A (en) 1985-05-09
SE8405450D0 (en) 1984-10-31
DK517484D0 (en) 1984-10-30
DK517484A (en) 1985-05-02

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Effective date: 19870501