SE8403929L - RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION - Google Patents
RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATIONInfo
- Publication number
- SE8403929L SE8403929L SE8403929A SE8403929A SE8403929L SE 8403929 L SE8403929 L SE 8403929L SE 8403929 A SE8403929 A SE 8403929A SE 8403929 A SE8403929 A SE 8403929A SE 8403929 L SE8403929 L SE 8403929L
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- penicillin
- recombinant dna
- dna molecule
- amidas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/84—Penicillin amidase (3.5.1.11)
Abstract
A recombinant DNA molecule comprising at least one DNA sequence coding for penicillin V amidase or a derivative thereof, and to a process for its preparation. The invention also relates to microorganisms transformed by said recombinant DNA molecule and to a porocess for their preparation. The invention further relates to a process for preparing penicillin V amidase and to the amidase produced thereby.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8403929A SE8403929L (en) | 1984-07-31 | 1984-07-31 | RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION |
JP50341285A JPS61502799A (en) | 1984-07-31 | 1985-07-19 | Recombinant DNA molecules, transformed microorganisms, and methods for producing penicillin V amidase |
EP19850903887 EP0190252A1 (en) | 1984-07-31 | 1985-07-19 | Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase |
PCT/SE1985/000287 WO1986000929A1 (en) | 1984-07-31 | 1985-07-19 | Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase |
DK141586A DK141586A (en) | 1984-07-31 | 1986-03-26 | RECOMBINANT DNA MOLECULE, PROCEDURES FOR PREPARING THEREOF, MICROORGANISMS TRANSFORMED THEREOF AND PROCEDURE FOR PENICILLIN-V-AMIDASE PREPARATION |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8403929A SE8403929L (en) | 1984-07-31 | 1984-07-31 | RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8403929D0 SE8403929D0 (en) | 1984-07-31 |
SE8403929L true SE8403929L (en) | 1986-02-21 |
Family
ID=20356635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8403929A SE8403929L (en) | 1984-07-31 | 1984-07-31 | RECOMBINANT DNA MOLECULE, TRANSFORMED MICROORGANISMS AND PROCEDURE FOR PENICILLIN V-AMIDAS PREPARATION |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0190252A1 (en) |
JP (1) | JPS61502799A (en) |
DK (1) | DK141586A (en) |
SE (1) | SE8403929L (en) |
WO (1) | WO1986000929A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9400650D0 (en) * | 1994-01-14 | 1994-03-09 | Smithkline Beecham Biolog | Expression of surface lazer proteins |
US5516679A (en) * | 1994-12-23 | 1996-05-14 | Bristol-Myers Squibb Company | Penicillin V amidohydrolase gene from Fusarium oxysporum |
HU226348B1 (en) | 1996-11-05 | 2008-09-29 | Bristol Myers Squibb Co | Mutant penicillin g acylases |
WO2015151118A1 (en) | 2014-04-04 | 2015-10-08 | Council Of Scientific & Industrial Research | A recombinant penicillin v acylase and process for the prepartion thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2048894A (en) * | 1979-05-11 | 1980-12-17 | Gist Brocades Nv | Plasmid |
AU545912B2 (en) * | 1980-03-10 | 1985-08-08 | Cetus Corporation | Cloned heterologous jive products in bacillies |
NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
DE3330003A1 (en) * | 1982-10-21 | 1984-10-31 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | DNA SEQUENCE AND STRUCTURES AND METHOD FOR THE PRODUCTION OF PENICILLIN ACYLASE THEREOF |
-
1984
- 1984-07-31 SE SE8403929A patent/SE8403929L/en not_active Application Discontinuation
-
1985
- 1985-07-19 EP EP19850903887 patent/EP0190252A1/en active Pending
- 1985-07-19 JP JP50341285A patent/JPS61502799A/en active Pending
- 1985-07-19 WO PCT/SE1985/000287 patent/WO1986000929A1/en not_active Application Discontinuation
-
1986
- 1986-03-26 DK DK141586A patent/DK141586A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK141586D0 (en) | 1986-03-26 |
EP0190252A1 (en) | 1986-08-13 |
JPS61502799A (en) | 1986-12-04 |
SE8403929D0 (en) | 1984-07-31 |
WO1986000929A1 (en) | 1986-02-13 |
DK141586A (en) | 1986-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 8403929-6 Effective date: 19880301 |