SE8302026L - 2-substituted-3-INDOLAMINER - Google Patents

2-substituted-3-INDOLAMINER

Info

Publication number
SE8302026L
SE8302026L SE8302026A SE8302026A SE8302026L SE 8302026 L SE8302026 L SE 8302026L SE 8302026 A SE8302026 A SE 8302026A SE 8302026 A SE8302026 A SE 8302026A SE 8302026 L SE8302026 L SE 8302026L
Authority
SE
Sweden
Prior art keywords
alkyl
represents hydrogen
image
formula
alkoxy
Prior art date
Application number
SE8302026A
Other languages
Swedish (sv)
Other versions
SE8302026D0 (en
Inventor
L J Brand
J Nadelson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8302026D0 publication Critical patent/SE8302026D0/en
Publication of SE8302026L publication Critical patent/SE8302026L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds of the general formula <IMAGE> (R1 represents hydrogen, fluorine, chlorine, C1-4 alkyl or C1-4 alkoxy, R2 and R3 represent C1-4 alkyl or, together with the adjacent nitrogen, pyrrolidino, piperidino, hexamethylenimino or morpholino, R represents a group of formula <IMAGE> X represents hydrogen and m represents 2, 3 or 4; or R represents biphenyl, naphthyl, benzylphenyl, indanyl, fluorenyl or a group of formula <IMAGE> X represents hydrogen or hydroxy and m represents 1, 2, 3 or 4, R4 represents hydrogen of C1-4 alkyl, R5 represents hydrogen, C1-4 alkyl, phenyl or phenyl substituted by halogen, C1-4 alkyl or C1-4 alkoxy) and their salts are antidiabetics.
SE8302026A 1982-04-13 1983-04-12 2-substituted-3-INDOLAMINER SE8302026L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36793882A 1982-04-13 1982-04-13
US38722482A 1982-06-10 1982-06-10

Publications (2)

Publication Number Publication Date
SE8302026D0 SE8302026D0 (en) 1983-04-12
SE8302026L true SE8302026L (en) 1983-10-14

Family

ID=27003990

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8302026A SE8302026L (en) 1982-04-13 1983-04-12 2-substituted-3-INDOLAMINER

Country Status (15)

Country Link
AU (1) AU1344083A (en)
BE (1) BE896421A (en)
CH (1) CH656124A5 (en)
DE (1) DE3312107A1 (en)
DK (1) DK159283A (en)
ES (1) ES521398A0 (en)
FI (1) FI831165L (en)
FR (1) FR2524881B1 (en)
GB (1) GB2119372B (en)
IL (1) IL68351A0 (en)
IT (1) IT1197628B (en)
NL (1) NL8301289A (en)
NZ (1) NZ203862A (en)
PT (1) PT76530B (en)
SE (1) SE8302026L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9111010B (en) * 1990-06-07 2005-02-28 Astrazeneca Ab 3,5-disubstituted indole derivatives as "5-ht1-similar" receptor agonists
GB9523999D0 (en) 1995-11-23 1996-01-24 Lilly Co Eli Indolyl neuropeptide y receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083566A1 (en) * 1980-04-10 1983-07-13 Sandoz Ag Isoxazolyl indoles
US4336391A (en) * 1981-04-06 1982-06-22 Sandoz, Inc. Isoxazolyl indolamines

Also Published As

Publication number Publication date
IT1197628B (en) 1988-12-06
PT76530A (en) 1983-05-01
AU1344083A (en) 1983-10-20
DK159283A (en) 1983-10-14
FR2524881B1 (en) 1985-09-20
FI831165L (en) 1983-10-14
ES8500904A1 (en) 1984-11-01
CH656124A5 (en) 1986-06-13
IT8348099A0 (en) 1983-04-13
FR2524881A1 (en) 1983-10-14
SE8302026D0 (en) 1983-04-12
NL8301289A (en) 1983-11-01
PT76530B (en) 1986-01-24
DK159283D0 (en) 1983-04-11
FI831165A0 (en) 1983-04-06
ES521398A0 (en) 1984-11-01
BE896421A (en) 1983-10-11
GB8309729D0 (en) 1983-05-18
NZ203862A (en) 1986-06-11
IL68351A0 (en) 1983-07-31
GB2119372B (en) 1985-09-18
GB2119372A (en) 1983-11-16
DE3312107A1 (en) 1983-10-20

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