SE8301072L - 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE - Google Patents

1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Info

Publication number
SE8301072L
SE8301072L SE8301072A SE8301072A SE8301072L SE 8301072 L SE8301072 L SE 8301072L SE 8301072 A SE8301072 A SE 8301072A SE 8301072 A SE8301072 A SE 8301072A SE 8301072 L SE8301072 L SE 8301072L
Authority
SE
Sweden
Prior art keywords
preparation
pharmaceutical preparations
preparations containing
dihydropyridine derivatives
dihydropyridine
Prior art date
Application number
SE8301072A
Other languages
Swedish (sv)
Other versions
SE8301072D0 (en
Inventor
A Vogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8301072D0 publication Critical patent/SE8301072D0/en
Publication of SE8301072L publication Critical patent/SE8301072L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

1,4-dihydropyridine-3,5-dicarbonic acid esters which are substituted on the pyridine ring, in a position next to the nitrogen by a cyan group and in a position opposite to the nitrogen atom by a condensated cyclic system containing at least two different heteroatoms and at least one aromatic ring, in particular the compounds having the formula I, are calcium antagonists. They may be used as drugs. The are obtained by cyanuration or N-substitution.
SE8301072A 1982-03-10 1983-02-25 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE SE8301072L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH147782 1982-03-10

Publications (2)

Publication Number Publication Date
SE8301072D0 SE8301072D0 (en) 1983-02-25
SE8301072L true SE8301072L (en) 1983-09-11

Family

ID=4211396

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8301072A SE8301072L (en) 1982-03-10 1983-02-25 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE

Country Status (17)

Country Link
JP (1) JPS58180483A (en)
AU (1) AU1169583A (en)
BE (1) BE895957A (en)
CH (1) CH660190A5 (en)
DE (1) DE3305577A1 (en)
DK (1) DK63583A (en)
ES (1) ES520201A0 (en)
FI (1) FI830617L (en)
FR (1) FR2523128B1 (en)
GB (1) GB2117761B (en)
IL (1) IL68005A0 (en)
IT (1) IT1197588B (en)
NL (1) NL8300739A (en)
PT (1) PT76290B (en)
SE (1) SE8301072L (en)
WO (1) WO1983003097A1 (en)
ZA (1) ZA83959B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
JP2002202369A (en) * 2000-12-27 2002-07-19 Nikon Corp Light signal detector and range finder
CN102766137B (en) * 2012-08-07 2015-07-08 四川百利药业有限责任公司 Method for preparing high-purity isradipine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
CH639659A5 (en) * 1978-12-18 1983-11-30 Sandoz Ag NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.
DK149855C (en) * 1977-06-20 1987-04-21 Sandoz Ag METHOD OF ANALOGY FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINE DERIVATIVES
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
CA1117117A (en) * 1978-10-10 1982-01-26 Fujisawa Pharmaceutical Co., Ltd. 2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
DE2949464A1 (en) * 1978-12-18 1980-06-26 Sandoz Ag BENZOXADIAZOLES AND BENZOTHIADIAZOLES, THEIR PRODUCTION AND USE
FI793848A (en) * 1978-12-18 1980-06-19 Sandoz Ag BENZOXADIAZOLER OCH BENZOTHIADIAZOLER DERAS FRAMSTAELLNING OCH PHARMACEUTICAL COMPOSITION INNEHAOLLANDE DESSA
GB2050375B (en) * 1979-05-11 1983-02-23 Fujisawa Pharmaceutical Co 4-cyanophenyl-1,4-dihydropyridine compound processes for preparation thereof and pharmaceutical composition comprising the same
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals

Also Published As

Publication number Publication date
DK63583D0 (en) 1983-02-14
ES8500057A1 (en) 1984-10-01
IT8347806A0 (en) 1983-02-25
ZA83959B (en) 1984-09-26
BE895957A (en) 1983-08-22
JPS58180483A (en) 1983-10-21
WO1983003097A1 (en) 1983-09-15
NL8300739A (en) 1983-10-03
IL68005A0 (en) 1983-06-15
FR2523128B1 (en) 1985-10-18
DE3305577A1 (en) 1983-09-22
GB8305525D0 (en) 1983-03-30
FI830617L (en) 1983-09-11
GB2117761B (en) 1986-01-29
SE8301072D0 (en) 1983-02-25
ES520201A0 (en) 1984-10-01
GB2117761A (en) 1983-10-19
PT76290B (en) 1985-12-03
FR2523128A1 (en) 1983-09-16
AU1169583A (en) 1983-09-15
CH660190A5 (en) 1987-03-31
DK63583A (en) 1983-09-11
IT1197588B (en) 1988-12-06
FI830617A0 (en) 1983-02-24
PT76290A (en) 1983-03-01

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